Cell autonomous requirement of connexin 43 for osteocyte survival: consequences for endocortical resorption and periosteal bone formation. (Q35729489)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22028311%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Cell autonomous requirement of connexin 43 for osteocyte survival: consequences for endocortical resorption and periosteal bone formation (English)

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15 January 2020

3

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15 January 2020

Yumie Rhee

7

1 reference

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15 January 2020

8

Teresita Bellido

1 reference

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15 January 2020

author name string

Nicoletta Bivi

1

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15 January 2020

Keith W Condon

2

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15 January 2020

Nathan Farlow

4

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15 January 2020

Giovanni Passeri

5

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15 January 2020

Lucas R Brun

6

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15 January 2020

Lilian I Plotkin

9

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15 January 2020

language of work or name

1 reference

1 February 2012

1 reference

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Journal of Bone and Mineral Research

15 January 2020

published in

1 reference

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15 January 2020

volume

27

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15 January 2020

issue

2

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15 January 2020

page(s)

374-389

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Parathyroid hormone receptor signaling in osteocytes increases the expression of fibroblast growth factor-23 in vitro and in vivo

15 January 2020

cites work

1 reference

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Connexin43 interacts with βarrestin: a pre-requisite for osteoblast survival induced by parathyroid hormone

12 July 2018

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Conditional deletion of Pkd1 in osteocytes disrupts skeletal mechanosensing in mice

12 July 2018

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Osteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodeling

12 July 2018

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PTH receptor signaling in osteocytes governs periosteal bone formation and intracortical remodeling.

12 July 2018

1 reference

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A bisphosphonate that does not affect osteoclasts prevents osteoblast and osteocyte apoptosis and the loss of bone strength induced by glucocorticoids in mice

12 July 2018

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Mechanical induction of PGE2 in osteocytes blocks glucocorticoid-induced apoptosis through both the β-catenin and PKA pathways

12 July 2018

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Sclerostin: a gem from the genome leads to bone-building antibodies

12 July 2018

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Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis

12 July 2018

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TGFbeta inducible early gene-1 directly binds to, and represses, the OPG promoter in osteoblasts

12 July 2018

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Osteocyte apoptosis and control of bone resorption following ovariectomy in mice

12 July 2018

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Identification of differentially expressed genes between osteoblasts and osteocytes

12 July 2018

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Sca-1+ stem cell survival and engraftment in the infarcted heart: dual role for preconditioning-induced connexin-43.

12 July 2018

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Bone morphogenetic protein-2 enhances Wnt/beta-catenin signaling-induced osteoprotegerin expression

12 July 2018

1 reference

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Depression of intraocular pressure following inactivation of connexin43 in the nonpigmented epithelium of the ciliary body

12 July 2018

1 reference

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Giant osteoclast formation and long-term oral bisphosphonate therapy

12 July 2018

1 reference

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Osteocyte apoptosis controls activation of intracortical resorption in response to bone fatigue

12 July 2018

1 reference

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Control of bone mass and remodeling by PTH receptor signaling in osteocytes

12 July 2018

1 reference

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Connexin 43 is required for the anti-apoptotic effect of bisphosphonates on osteocytes and osteoblasts in vivo

12 July 2018

1 reference

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Alendronate reduces bone toughness of ribs without significantly increasing microdamage accumulation in dogs following 3 years of daily treatment.

12 July 2018

1 reference

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Apoptotic bodies convey activity capable of initiating osteoclastogenesis and localized bone destruction

12 July 2018

1 reference

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Cell-cell communication in the osteoblast/osteocyte lineage.

12 July 2018

1 reference

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Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation

12 July 2018

1 reference

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Attenuated response to in vivo mechanical loading in mice with conditional osteoblast ablation of the connexin43 gene (Gja1).

12 July 2018

1 reference

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Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin

12 July 2018

1 reference

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The conditional connexin43G138R mouse mutant represents a new model of hereditary oculodentodigital dysplasia in humans.

12 July 2018

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Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids

12 July 2018

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DMP1-targeted Cre expression in odontoblasts and osteocytes

12 July 2018

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Oscillating fluid flow activation of gap junction hemichannels induces ATP release from MLO-Y4 osteocytes.

12 July 2018

1 reference

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The influence of mechanical stimulation on osteocyte apoptosis and bone viability in human trabecular bone.

12 July 2018

1 reference

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Osteoblasts and osteocytes respond differently to oscillatory and unidirectional fluid flow profiles

12 July 2018

1 reference

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Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesis

12 July 2018

1 reference

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SOST is a target gene for PTH in bone

12 July 2018

1 reference

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Mechanical stimulation prevents osteocyte apoptosis: requirement of integrins, Src kinases, and ERKs

12 July 2018

1 reference

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Mechanical strain opens connexin 43 hemichannels in osteocytes: a novel mechanism for the release of prostaglandin

12 July 2018

1 reference

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Gap junctions regulate extracellular signal-regulated kinase signaling to affect gene transcription

12 July 2018

1 reference

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Gap junctions and connexin-interacting proteins

12 July 2018

1 reference

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Gap junctional communication modulates gene transcription by altering the recruitment of Sp1 and Sp3 to connexin-response elements in osteoblast promoters.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271138

Beyond the gap: functions of unpaired connexon channels

12 July 2018

1 reference

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Connexin 43 (GJA1) mutations cause the pleiotropic phenotype of oculodentodigital dysplasia

12 July 2018

1 reference

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MLO-Y4 osteocyte-like cells support osteoclast formation and activation

12 July 2018

1 reference

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Transduction of cell survival signals by connexin-43 hemichannels

12 July 2018

1 reference

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Renal morphology in connexin43 knockout mice

12 July 2018

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Connexin43 deficiency causes delayed ossification, craniofacial abnormalities, and osteoblast dysfunction

12 July 2018

1 reference

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Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin

12 July 2018

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Missing observations in bone histomorphometry on osteoporosis: implications and suggestions for an approach

12 July 2018

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Increased expression of TGF-beta 2 in osteoblasts results in an osteoporosis-like phenotype

12 July 2018

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Cardiac malformation in neonatal mice lacking connexin43.

12 July 2018

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Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee

12 July 2018

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Targeted oncogene activation by site-specific recombination in transgenic mice

12 July 2018

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Tissue- and site-specific DNA recombination in transgenic mice

12 July 2018

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Transcriptome and proteome analysis of osteocytes treated with nitrogen-containing bisphosphonates

12 July 2018

1 reference

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Activation of the p53 pathway down-regulates the osteoprotegerin expression and release by vascular endothelial cells

25 September 2018

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Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor- to forkhead box O-mediated transcription.

25 September 2018

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Low peak bone mass and attenuated anabolic response to parathyroid hormone in mice with an osteoblast-specific deletion of connexin43.

25 September 2018

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Primordial germ cell deficiency in the connexin 43 knockout mouse arises from apoptosis associated with abnormal p53 activation.

25 September 2018

1 reference

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Osteocyte apoptosis is induced by weightlessness in mice and precedes osteoclast recruitment and bone loss.

25 September 2018

1 reference

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Shear stress inhibits while disuse promotes osteocyte apoptosis

25 September 2018

1 reference

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Dentin matrix protein 1 expression during osteoblastic differentiation, generation of an osteocyte GFP-transgene.

25 September 2018

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Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts. A putative explanation for why intermittent administration is needed for bone anabolism

25 September 2018

1 reference

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Mechanical loading: biphasic osteocyte survival and targeting of osteoclasts for bone destruction in rat cortical bone.

25 September 2018

1 reference

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Age and distance from the surface but not menopause reduce osteocyte density in human cancellous bone.

25 September 2018

1 reference

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Osteocyte apoptosis induces bone resorption and impairs the skeletal response to weightlessness

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FJBMR.548

Effects of hind limb unloading and reloading on nitric oxide synthase expression and apoptosis of osteocytes and chondrocytes

21 January 2018

1 reference

12 December 2020

Wnt/beta-catenin signaling is a normal physiological response to mechanical loading in bone

1 reference

12 December 2020

Skeletal unloading induces osteoblast apoptosis and targets alpha5beta1-PI3K-Bcl-2 signaling in rat bone

1 reference

12 December 2020

Targeted overexpression of insulin-like growth factor I to osteoblasts of transgenic mice: increased trabecular bone volume without increased osteoblast proliferation

1 reference

12 December 2020

Endothelium-specific replacement of the connexin43 coding region by a lacZ reporter gene

1 reference

12 December 2020

Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction

1 reference

12 December 2020

A novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblast mechanotransduction

1 reference

12 December 2020

Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization

1 reference

12 December 2020

Multiple extracellular signals promote osteoblast survival and apoptosis

1 reference

12 December 2020

Death of osteocytes turns off the inhibition of osteoclasts and triggers local bone resorption

1 reference

12 December 2020

Identifiers

DOI

10.1002/JBMR.548

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22028311%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22028311%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

22028311

1 reference