Germinal center-associated nuclear protein contributes to affinity maturation of B cell antigen receptor in T cell-dependent responses. (Q35731798)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14715907%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

title

Germinal center-associated nuclear protein contributes to affinity maturation of B cell antigen receptor in T cell-dependent responses (English)

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17 November 2019

3

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17 November 2019

Naomi Nakagata

4

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17 November 2019

author name string

Kazuhiko Kuwahara

1

1 reference

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17 November 2019

Satoru Fujimura

2

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17 November 2019

Toshitada Takemori

5

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17 November 2019

Shinichi Aizawa

6

1 reference

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17 November 2019

Nobuo Sakaguchi

7

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17 November 2019

language of work or name

English

0 references

publication date

8 January 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14715907%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

17 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14715907%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

volume

101

1 reference

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17 November 2019

issue

4

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17 November 2019

page(s)

1010-1015

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Immunoglobulin genes: generating diversity with AID and UNG.

17 November 2019

cites work

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21 January 2018

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Prevention of B cell antigen receptor-induced apoptosis by ligation of CD40 occurs downstream of cell cycle regulation.

12 July 2018

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AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line

12 July 2018

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BAFF: a fundamental survival factor for B cells.

12 July 2018

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Molecular mechanism of class switch recombination: linkage with somatic hypermutation

12 July 2018

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Germinal center-associated nuclear protein (GANP) has a phosphorylation-dependent DNA-primase activity that is up-regulated in germinal center regions

12 July 2018

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Expression of error-prone polymerases in BL2 cells activated for Ig somatic hypermutation

12 July 2018

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DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes

12 July 2018

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The translesion DNA polymerase zeta plays a major role in Ig and bcl-6 somatic hypermutation.

12 July 2018

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MCM3AP, a novel acetyltransferase that acetylates replication protein MCM3

12 July 2018

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Signals that initiate somatic hypermutation of B cells in vitro

12 July 2018

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Structure, expression, and chromosomal localization of the human gene encoding a germinal center-associated nuclear protein (GANP) that associates with MCM3 involved in the initiation of DNA replication

12 July 2018

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Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

12 July 2018

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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

12 July 2018

1 reference

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A novel nuclear phosphoprotein, GANP, is up-regulated in centrocytes of the germinal center and associated with MCM3, a protein essential for DNA replication

12 July 2018

1 reference

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12 July 2018

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Interleukin 6 influences germinal center development and antibody production via a contribution of C3 complement component

12 July 2018

1 reference

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Antigen receptor cross-linking by anti-immunoglobulin antibodies coupled to cell surface membrane induces rapid apoptosis of normal spleen B cells

12 July 2018

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A DNA helicase activity is associated with an MCM4, -6, and -7 protein complex

12 July 2018

1 reference

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Germinal center development

12 July 2018

1 reference

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Apoptosis and the B cell response to antigen

12 July 2018

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Lymphotoxin-alpha-deficient and TNF receptor-I-deficient mice define developmental and functional characteristics of germinal centers

12 July 2018

1 reference

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The physiology of murine germinal center reactions

12 July 2018

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B lymphocyte-specific, Cre-mediated mutagenesis in mice

12 July 2018

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Altered antigen receptor signaling and impaired Fas-mediated apoptosis of B cells in Lyn-deficient mice

12 July 2018

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Bcl-x rather than Bcl-2 mediates CD40-dependent centrocyte survival in the germinal center

12 July 2018

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Clonal selection and learning in the antibody system

12 July 2018

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12 July 2018

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In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells

12 July 2018

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A novel ES cell line, TT2, with high germline-differentiating potency

12 July 2018

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12 July 2018

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Bcl-2 increases memory B cell recruitment but does not perturb selection in germinal centers.

12 July 2018

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Anti-CD40 monoclonal antibody induces the proliferation of murine B cells as a B-cell mitogen through a distinct pathway from receptors for antigens or lipopolysaccharide

12 July 2018

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The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation

12 July 2018

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Somatic generation of antibody diversity

12 July 2018

1 reference

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V(D)J recombination: molecular biology and regulation

12 July 2018

1 reference

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12 July 2018

1 reference

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Somatic mutation hotspots correlate with DNA polymerase eta error spectrum.

12 July 2018

1 reference

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Follicular dendritic cells and presentation of antigen and costimulatory signals to B cells

21 January 2018

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Methamphetamine causes differential regulation of pro-death and anti-death Bcl-2 genes in the mouse neocortex

21 January 2018

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Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire

21 January 2018

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CD28 is required for germinal center formation.

21 January 2018

1 reference

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Role of bcl-2 and IL-5 in the regulation of anti-IgM-induced growth arrest and apoptosis in immature B cell lines. A cooperative regulation model for B cell clonal deletion.

25 September 2018

1 reference

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Generation and analysis of interleukin-4 deficient mice

25 September 2018

1 reference

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Decreased Frequency of Somatic Hypermutation and Impaired Affinity Maturation but Intact Germinal Center Formation in Mice Expressing Antisense RNA to DNA Polymerase

21 January 2018

1 reference

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Structure of primary anti-(4-hydroxy-3-nitrophenyl)acetyl (NP) antibodies in normal and idiotypically suppressed C57BL/6 mice

21 January 2018

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Mice deficient for the CD40 ligand

21 January 2018

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21 January 2018

Identifiers

DOI

10.1073/PNAS.0307609100

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14715907%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14715907%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

PubMed publication ID

14715907

1 reference