Differential mTOR and ERK pathway utilization by effector CD4 T cells suggests combinatorial drug therapy of arthritis (Q35739928)

10 August 2017

title

Differential mTOR and ERK pathway utilization by effector CD4 T cells suggests combinatorial drug therapy of arthritis (English)

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10 August 2017

Jack T Lin

1

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10 August 2017

Emily A Stein

2

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10 August 2017

Michael T Wong

3

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10 August 2017

Krishna J Kalpathy

4

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10 August 2017

Leon L Su

5

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10 August 2017

Paul J Utz

6

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10 August 2017

William H Robinson

7

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10 August 2017

C Garrison Fathman

8

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10 August 2017

publication date

1 October 2011

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10 August 2017

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10 August 2017

volume

142

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10 August 2017

issue

2

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10 August 2017

page(s)

127-138

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The mammalian target of rapamycin: linking T cell differentiation, function, and metabolism

10 August 2017

cites work

1 reference

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27 July 2018

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Effector and regulatory T-cell subsets in autoimmunity and tissue inflammation

27 July 2018

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27 July 2018

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Naive CD4 t cell proliferation is controlled by mammalian target of rapamycin regulation of GRAIL expression

27 July 2018

1 reference

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Immunoregulatory functions of mTOR inhibition.

27 July 2018

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The RSK family of kinases: emerging roles in cellular signalling

27 July 2018

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Single-cell phospho-protein analysis by flow cytometry

27 July 2018

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Distinct regulation of effector and memory T-cell differentiation.

27 July 2018

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The selectivity of protein kinase inhibitors: a further update

27 July 2018

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RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation

27 July 2018

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New reagents on the horizon for immune tolerance

27 July 2018

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The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity

27 July 2018

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27 July 2018

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T-cell tolerance and autoimmunity to systemic and tissue-restricted self-antigens

27 July 2018

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The CD28 family: a T-cell rheostat for therapeutic control of T-cell activation.

27 July 2018

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Central memory and effector memory T cell subsets: function, generation, and maintenance

27 July 2018

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27 July 2018

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In vivo activation of antigen-specific CD4 T cells.

27 July 2018

1 reference

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The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

27 July 2018

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Rapamycin prevents the onset of insulin-dependent diabetes mellitus (IDDM) in NOD mice

27 July 2018

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Rapamycin inhibits relapsing experimental autoimmune encephalomyelitis by both effector and regulatory T cells modulation.

27 July 2018

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MAPK, phosphatidylinositol 3-kinase, and mammalian target of rapamycin pathways converge at the level of ribosomal protein S6 phosphorylation to control metabolic signaling in CD8 T cells

25 September 2018

1 reference

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Treatment with rapamycin ameliorates clinical and histological signs of protracted relapsing experimental allergic encephalomyelitis in Dark Agouti rats and induces expansion of peripheral CD4+CD25+Foxp3+ regulatory T cells.

25 September 2018

1 reference

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The biology of interleukin-2.

25 September 2018

1 reference

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Accumulation of NFAT mediates IL-2 expression in memory, but not naïve, CD4+ T cells

25 September 2018

1 reference

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Signalling to translation: how signal transduction pathways control the protein synthetic machinery

25 September 2018

1 reference

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Prolonged TCR/CD28 engagement drives IL-2-independent T cell clonal expansion through signaling mediated by the mammalian target of rapamycin

25 September 2018

1 reference

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A role for mammalian target of rapamycin in regulating T cell activation versus anergy

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22075384

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CLIM.2011.09.008

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10 August 2017

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10 August 2017

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