A hot-spot motif characterizes the interface between a designed ankyrin-repeat protein and its target ligand. (Q35743283)

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22 January 2020

title

A hot-spot motif characterizes the interface between a designed ankyrin-repeat protein and its target ligand (English)

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22 January 2020

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3

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22 January 2020

author name string

Luthur Siu-Lun Cheung

series ordinal

1

1 reference

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22 January 2020

Manu Kanwar

series ordinal

2

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22 January 2020

Konstantinos Konstantopoulos

series ordinal

4

1 reference

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22 January 2020

language of work or name

English

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publication date

7 February 2012

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22 January 2020

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22 January 2020

volume

102

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22 January 2020

issue

3

1 reference

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22 January 2020

page(s)

407-416

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All-atom empirical potential for molecular modeling and dynamics studies of proteins

22 January 2020

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1 reference

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Quantitation of protein-protein interactions by thermal stability shift analysis

27 July 2018

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Protein switches identified from diverse insertion libraries created using S1 nuclease digestion of supercoiled-form plasmid DNA

27 July 2018

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Single-molecule binding of CD44 to fibrin versus P-selectin predicts their distinct shear-dependent interactions in cancer

27 July 2018

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Grading the commercial optical biosensor literature-Class of 2008: 'The Mighty Binders'.

27 July 2018

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Knowledge-based design of reagentless fluorescent biosensors from a designed ankyrin repeat protein

27 July 2018

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Selection and characterization of DARPins specific for the neurotensin receptor 1

27 July 2018

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27 July 2018

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Biomolecular characterization of CD44-fibrin(ogen) binding: distinct molecular requirements mediate binding of standard and variant isoforms of CD44 to immobilized fibrin(ogen)

27 July 2018

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Chaperone-assisted crystallography with DARPins

27 July 2018

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Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy

27 July 2018

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Carcinoembryonic antigen and CD44 variant isoforms cooperate to mediate colon carcinoma cell adhesion to E- and L-selectin in shear flow

27 July 2018

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Hot spots--a review of the protein-protein interface determinant amino-acid residues

27 July 2018

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Forces and bond dynamics in cell adhesion.

27 July 2018

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High-affinity single-domain binding proteins with a binary-code interface

27 July 2018

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Selection and characterization of Her2 binding-designed ankyrin repeat proteins

27 July 2018

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Scalable molecular dynamics with NAMD

27 July 2018

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Allosteric inhibition of aminoglycoside phosphotransferase by a designed ankyrin repeat protein

27 July 2018

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Directed evolution of protein switches and their application to the creation of ligand-binding proteins.

27 July 2018

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High-affinity binders selected from designed ankyrin repeat protein libraries

27 July 2018

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Direct observation of catch bonds involving cell-adhesion molecules

27 July 2018

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Designed to be stable: crystal structure of a consensus ankyrin repeat protein

27 July 2018

1 reference

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A simple physical model for binding energy hot spots in protein-protein complexes

27 July 2018

1 reference

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Molecular properties in cell adhesion: a physical and engineering perspective

27 July 2018

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A microcantilever device to assess the effect of force on the lifetime of selectin-carbohydrate bonds

27 July 2018

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Measuring two-dimensional receptor-ligand binding kinetics by micropipette

27 July 2018

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Anatomy of hot spots in protein interfaces

27 July 2018

1 reference

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Two modes of ligand binding in maltose-binding protein of Escherichia coli. Functional significance in active transport

27 July 2018

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Kinetic analysis of biosensor data: elementary tests for self-consistency.

27 July 2018

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27 July 2018

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27 July 2018

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Models for the Specific Adhesion of Cells to Cells

27 July 2018

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Integration of cell-free protein coexpression with an enzyme-linked immunosorbent assay enables rapid analysis of protein-protein interactions directly from DNA.

27 July 2018

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Inhibition of caspase-2 by a designed ankyrin repeat protein: specificity, structure, and inhibition mechanism

25 September 2018

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Rapid selection of specific MAP kinase-binders from designed ankyrin repeat protein libraries

25 September 2018

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Single-molecule analysis of cadherin-mediated cell-cell adhesion.

25 September 2018

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Hot regions in protein--protein interactions: the organization and contribution of structurally conserved hot spot residues

25 September 2018

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A molecular switch created by in vitro recombination of nonhomologous genes.

25 September 2018

1 reference

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Distinct kinetic and mechanical properties govern selectin-leukocyte interactions

25 September 2018

1 reference

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The role of the CD44 transmembrane and cytoplasmic domains in co-ordinating adhesive and signalling events.

25 September 2018

1 reference

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ASEdb: a database of alanine mutations and their effects on the free energy of binding in protein interactions

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274810

Dissecting protein-protein recognition sites

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22325262

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Single molecule characterization of P-selectin/ligand binding

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22325262

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BPJ.2012.01.004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22325262%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22325262%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

22325262

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22325262%20AND%20SRC:MED&resulttype=core&format=json