Glucuronidation of trans-3'-hydroxycotinine by UGT2B17 and UGT2B10. (Q35745357)

10 August 2017

title

Glucuronidation of trans-3'-hydroxycotinine by UGT2B17 and UGT2B10. (English)

1 reference

10 August 2017

main subject

trans-3-hydroxycotinine

1 reference

ChEBI release 2020-05-28

Gang Chen

1

1 reference

10 August 2017

Nino E Giambrone

series ordinal

2

1 reference

10 August 2017

Philip Lazarus

series ordinal

3

1 reference

10 August 2017

publication date

1 March 2012

1 reference

Pharmacogenetics and Genomics

10 August 2017

published in

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10 August 2017

volume

22

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10 August 2017

issue

3

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10 August 2017

page(s)

183-190

1 reference

Olanzapine metabolism and the significance of UGT1A448V and UGT2B1067Y variants.

10 August 2017

cites work

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Glucuronidation genotypes and nicotine metabolic phenotypes: importance of functional UGT2B10 and UGT2B17 polymorphisms

12 July 2018

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Sex Differences in UDP-Glucuronosyltransferase 2B17 Expression and Activity

12 July 2018

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Determination of mRNA Expression of Human UDP-Glucuronosyltransferases and Application for Localization in Various Human Tissues by Real-Time Reverse Transcriptase-Polymerase Chain Reaction

12 July 2018

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12 July 2018

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Identification of a prevalent functional missense polymorphism in the UGT2B10 gene and its association with UGT2B10 inactivation against tobacco-specific nitrosamines

12 July 2018

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Glucuronidation of tobacco-specific nitrosamines by UGT2B10

12 July 2018

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Glucuronidation of nicotine and cotinine by UGT2B10: loss of function by the UGT2B10 Codon 67 (Asp>Tyr) polymorphism

12 July 2018

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Glucuronidation of active tamoxifen metabolites by the human UDP glucuronosyltransferases

12 July 2018

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The UDP-glucuronosyltransferase 2B17 gene deletion polymorphism: sex-specific association with urinary 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol glucuronidation phenotype and risk for lung cancer

12 July 2018

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Importance of UDP-glucuronosyltransferase 1A10 (UGT1A10) in the detoxification of polycyclic aromatic hydrocarbons: decreased glucuronidative activity of the UGT1A10139Lys isoform

12 July 2018

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Genotype-phenotype correlation between the polymorphic UGT2B17 gene deletion and NNAL glucuronidation activities in human liver microsomes

12 July 2018

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Interindividual variability in nicotine metabolism: C-oxidation and glucuronidation

12 July 2018

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12 July 2018

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Characterization of N-glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in human liver: importance of UDP-glucuronosyltransferase 1A4

12 July 2018

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Determination of nicotine N-1-glucuronide, a quaternary N-glucuronide conjugate, in human biological samples

12 July 2018

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Relative enzymatic activity, protein stability, and tissue distribution of human steroid-metabolizing UGT2B subfamily members

12 July 2018

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O-Glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1- (3-pyridyl)-1-butanol (NNAL) by human UDP-glucuronosyltransferases 2B7 and 1A9.

12 July 2018

1 reference

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Nicotine metabolic profile in man: comparison of cigarette smoking and transdermal nicotine

12 July 2018

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Characterization of the glucuronide conjugate of cotinine: a previously unidentified major metabolite of nicotine in smokers' urine

12 July 2018

1 reference

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Tissue-specific mRNA expression profiles of human phase I metabolizing enzymes except for cytochrome P450 and phase II metabolizing enzymes

12 July 2018

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Trans-3'-hydroxycotinine O- and N-glucuronidations in human liver microsomes.

25 September 2018

1 reference

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Nicotine metabolite ratio as an index of cytochrome P450 2A6 metabolic activity

25 September 2018

1 reference

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Correlation between UDP-glucuronosyltransferase genotypes and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone glucuronidation phenotype in human liver microsomes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275669

N-glucuronidation of trans-3'-hydroxycotinine by human liver microsomes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275669

Formation of the quaternary ammonium-linked glucuronide of nicotine in human liver microsomes: identification and stereoselectivity in the kinetics

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275669

A general assay for UDPglucuronosyltransferase activity using polar amino-cyano stationary phase HPLC and UDP[U-14C]glucuronic acid.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275669

Characterization of a common deletion polymorphism of the UGT2B17 gene linked to UGT2B15

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22228205

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Rates of excretion of cotinine, nicotine glucuronide, and 3-hydroxycotinine glucuronide in rat bile

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22228205

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Direct determination of cotinine-N-glucuronide in urine using thermospray liquid chromatography/mass spectrometry

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22228205

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1097/FPC.0B013E32834FF3A5

1 reference

10 August 2017

1 reference

10 August 2017

1 reference