A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers. (Q35747423)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12107105%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers (English)

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10 November 2019

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8

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10 November 2019

Takashi Takahashi

9

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10 November 2019

10

Setsuo Hirohashi

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10 November 2019

author name string

Sana Yokoi

1

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10 November 2019

Kohichiroh Yasui

2

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10 November 2019

Fumiko Saito-Ohara

3

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10 November 2019

Katsumi Koshikawa

4

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10 November 2019

Toshihiko Iizasa

5

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10 November 2019

Takehiko Fujisawa

6

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10 November 2019

Takeo Terasaki

7

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10 November 2019

Johji Inazawa

11

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10 November 2019

language of work or name

English

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publication date

1 July 2002

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The American Journal of Pathology

10 November 2019

published in

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10 November 2019

volume

161

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10 November 2019

issue

1

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10 November 2019

page(s)

207-216

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describes a project that uses

10 November 2019

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Skp2 is oncogenic and overexpressed in human cancers

1 reference

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Role of the F-box protein Skp2 in lymphomagenesis

12 July 2018

1 reference

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CD44 is a potential target of amplification within the 11p13 amplicon detected in gastric cancer cell lines

12 July 2018

1 reference

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Identification of a novel gene, GASC1, within an amplicon at 9p23-24 frequently detected in esophageal cancer cell lines

12 July 2018

1 reference

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Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

12 July 2018

1 reference

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Survivin-deltaEx3 and survivin-2B: two novel splice variants of the apoptosis inhibitor survivin with different antiapoptotic properties

12 July 2018

1 reference

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p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850681

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

12 July 2018

1 reference

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p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

12 July 2018

1 reference

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Comparative genomic hybridization and chromosomal instability in solid tumours

12 July 2018

1 reference

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12 July 2018

Cancer statistics, 1999.

1 reference

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Typical and atypical carcinoid tumors of the lung are characterized by 11q deletions as detected by comparative genomic hybridization

12 July 2018

1 reference

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Identification of amplified DNA sequences on double minute chromosomes in a leukemic cell line KY821 by means of spectral karyotyping and comparative genomic hybridization

12 July 2018

1 reference

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Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins

12 July 2018

1 reference

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DNA copy number amplifications in human neoplasms: review of comparative genomic hybridization studies

12 July 2018

1 reference

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Loss of cyclin-dependent kinase inhibitor p27Kip1 is a novel prognostic factor in localized human prostate adenocarcinoma

12 July 2018

1 reference

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Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850681

Small-cell lung cancer is characterized by a high incidence of deletions on chromosomes 3p, 4q, 5q, 10q, 13q and 17p

12 July 2018

1 reference

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Glutathione S-transferase pi levels in a panel of lung cancer cell lines and its relation to chemo-radiosensitivity.

12 July 2018

1 reference

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Establishment of a human small cell lung cancer cell line producing a large amount of anti-diuretic hormone

12 July 2018

1 reference

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Isolation and sequence analysis of human cadherin-6 complementary DNA for the full coding sequence and its expression in human carcinoma cells

12 July 2018

1 reference

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Identification of novel regions of altered DNA copy number in small cell lung tumors

12 July 2018

1 reference

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p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

12 July 2018

1 reference

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Biological, pathological and clinical features of small cell lung cancer

12 July 2018

1 reference

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Changes in cell characteristics due to culture conditions in cell lines from human small cell lung cancer

12 July 2018

1 reference

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Human small-cell lung cancers show amplification and expression of the N-myc gene

12 July 2018

1 reference

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Coexpression of the stem cell factor and the c-kit genes in small-cell lung cancer

12 July 2018

1 reference

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Relation between Nucleolar Size and Growth Characteristics in Small Cell Lung Cancer Cell Lines

12 July 2018

1 reference

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Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors

12 July 2018

1 reference

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12 July 2018

1 reference

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12 July 2018

1 reference

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27 July 2018

1 reference

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25 September 2018

1 reference

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25 September 2018

1 reference

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25 September 2018

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25 September 2018

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25 September 2018

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25 September 2018

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25 September 2018

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Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12107105%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12107105%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

PubMed publication ID

12107105

1 reference