Polymerase ε (POLE) ultra-mutated tumors induce robust tumor-specific CD4+ T cell responses in endometrial cancer patients. (Q35748591)

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7 March 2020

title

Polymerase ε (POLE) ultra-mutated tumors induce robust tumor-specific CD4+ T cell responses in endometrial cancer patients (English)

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7 March 2020

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7

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Elena Bonazzoli

8

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7 March 2020

author name string

Stefania Bellone

1

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7 March 2020

Floriana Centritto

2

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Jonathan Black

3

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7 March 2020

Carlton Schwab

4

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Diana English

5

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7 March 2020

Emiliano Cocco

6

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Federica Predolini

9

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Francesca Ferrari

10

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Dan-Arin Silasi

11

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Elena Ratner

12

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Masoud Azodi

13

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Peter E Schwartz

14

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Alessandro D Santin

15

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7 March 2020

language of work or name

English

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publication date

27 April 2015

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7 March 2020

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7 March 2020

volume

138

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7 March 2020

issue

1

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7 March 2020

page(s)

11-17

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Improved survival of patients with hypermutation in uterine serous carcinoma

7 March 2020

cites work

1 reference

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Prognostic significance of POLE proofreading mutations in endometrial cancer.

12 July 2018

1 reference

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Genetic basis for clinical response to CTLA-4 blockade in melanoma

12 July 2018

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Clinicopathological analysis of endometrial carcinomas harboring somatic POLE exonuclease domain mutations

12 July 2018

1 reference

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Solitomab, an epithelial cell adhesion molecule/CD3 bispecific antibody (BiTE), is highly active against primary chemotherapy-resistant ovarian cancer cell lines in vitro and fresh tumor cells ex vivo

12 July 2018

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Integrated genomic characterization of endometrial carcinoma

12 July 2018

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DNA polymerase ε and δ exonuclease domain mutations in endometrial cancer

12 July 2018

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Germline and somatic polymerase ε and δ mutations define a new class of hypermutated colorectal and endometrial cancers

12 July 2018

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Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma

12 July 2018

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Early stage uterine serous carcinoma: management updates and genomic advances

12 July 2018

1 reference

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Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

12 July 2018

1 reference

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DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469551

DNA polymerase epsilon: a polymerase of unusual size (and complexity).

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469551

Human papillomavirus type 16 and 18 E7-pulsed dendritic cell vaccination of stage IB or IIA cervical cancer patients: a phase I escalating-dose trial.

12 July 2018

1 reference

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Induction of tumour-specific CD8(+) cytotoxic T lymphocytes by tumour lysate-pulsed autologous dendritic cells in patients with uterine serous papillary cancer

12 July 2018

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Induction of human papillomavirus-specific CD4(+) and CD8(+) lymphocytes by E7-pulsed autologous dendritic cells in patients with human papillomavirus type 16- and 18-positive cervical cancer

12 July 2018

1 reference

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Dendritic cells and the control of immunity

12 July 2018

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Specific T helper cell requirement for optimal induction of cytotoxic T lymphocytes against major histocompatibility complex class II negative tumors

12 July 2018

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Induction of a CD8+ cytotoxic T lymphocyte response by cross-priming requires cognate CD4+ T cell help

12 July 2018

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Major histocompatibility complex class II+B7-1+ tumor cells are potent vaccines for stimulating tumor rejection in tumor-bearing mice

12 July 2018

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Development of a lipopeptide-based therapeutic vaccine to treat chronic HBV infection. I. Induction of a primary cytotoxic T lymphocyte response in humans

12 July 2018

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Uterine papillary serous carcinoma: a highly malignant form of endometrial adenocarcinoma

12 July 2018

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Two pathogenetic types of endometrial carcinoma

12 July 2018

1 reference

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POLE exonuclease domain mutation predicts long progression-free survival in grade 3 endometrioid carcinoma of the endometrium.

12 July 2018

1 reference

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"License to kill" reflects joint action of CD4 and CD8 T cells

25 September 2018

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25 September 2018

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25 September 2018

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25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2015.04.027

10.1016/J.YGYNO.2015.04.027

7 January 2021

Identifiers

DOI

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7 March 2020

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7 March 2020

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