Chemical inhibition of the TFIIH-associated kinase Cdk7/Kin28 does not impair global mRNA synthesis. (Q35749517)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17392431%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

title

Chemical inhibition of the TFIIH-associated kinase Cdk7/Kin28 does not impair global mRNA synthesis (English)

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28 December 2019

6

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28 December 2019

author name string

Elenita I Kanin

1

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28 December 2019

Ryan T Kipp

2

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28 December 2019

Charles Kung

3

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28 December 2019

Matthew Slattery

4

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28 December 2019

Agnes Viale

5

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28 December 2019

Kevan M Shokat

7

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28 December 2019

Aseem Z Ansari

8

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28 December 2019

language of work or name

English

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publication date

28 March 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17392431%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

28 December 2019

published in

1 reference

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28 December 2019

volume

104

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28 December 2019

issue

14

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28 December 2019

page(s)

5812-5817

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Features of selective kinase inhibitors

28 December 2019

cites work

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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The FACT complex travels with elongating RNA polymerase II and is important for the fidelity of transcriptional initiation in vivo

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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Chemical inhibition of the Pho85 cyclin-dependent kinase reveals a role in the environmental stress response

27 July 2018

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Mediator--a universal complex in transcriptional regulation

27 July 2018

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Inability to enter S phase and defective RNA polymerase II CTD phosphorylation in mice lacking Mat1

27 July 2018

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Magic bullets for protein kinases

27 July 2018

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Remodeling of yeast genome expression in response to environmental changes

27 July 2018

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Genomic expression programs in the response of yeast cells to environmental changes

27 July 2018

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Transcription of eukaryotic protein-coding genes

27 July 2018

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Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription

27 July 2018

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Dynamic association of capping enzymes with transcribing RNA polymerase II

27 July 2018

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A chemical switch for inhibitor-sensitive alleles of any protein kinase

27 July 2018

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Mechanism of ATP-dependent promoter melting by transcription factor IIH

27 July 2018

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Kin28, the TFIIH-associated carboxy-terminal domain kinase, facilitates the recruitment of mRNA processing machinery to RNA polymerase II.

27 July 2018

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Mutations in XPB and XPD helicases found in xeroderma pigmentosum patients impair the transcription function of TFIIH.

27 July 2018

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Reconstitution of the transcription factor TFIIH: assignment of functions for the three enzymatic subunits, XPB, XPD, and cdk7

27 July 2018

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Dissecting the regulatory circuitry of a eukaryotic genome

27 July 2018

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27 July 2018

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Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases

27 July 2018

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Transcriptional activation independent of TFIIH kinase and the RNA polymerase II mediator in vivo.

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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A three-step pathway of transcription initiation leading to promoter clearance at an activation RNA polymerase II promoter

27 July 2018

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Phosphorylation of C-terminal domain of RNA polymerase II is not required in basal transcription

27 July 2018

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RAD25 is a DNA helicase required for DNA repair and RNA polymerase II transcription

27 July 2018

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Interplay of positive and negative effectors in function of the C-terminal repeat domain of RNA polymerase II

27 July 2018

1 reference

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Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK

27 July 2018

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RNA polymerase II phosphorylation: uncoupling from GAL4-VP16 directed open complex formation and transcription in a reconstituted system

27 July 2018

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A kinase-deficient transcription factor TFIIH is functional in basal and activated transcription

27 July 2018

1 reference

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KIN28 encodes a C-terminal domain kinase that controls mRNA transcription in Saccharomyces cerevisiae but lacks cyclin-dependent kinase-activating kinase (CAK) activity

27 July 2018

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Requirement for TFIIH kinase activity in transcription by RNA polymerase II

27 July 2018

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Transcription initiation complexes and upstream activation with RNA polymerase II lacking the C-terminal domain of the largest subunit

27 July 2018

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The carboxyl-terminal repeat domain of RNA polymerase II is not required for transcription factor Sp1 to function in vitro

27 July 2018

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27 July 2018

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Recent highlights of RNA-polymerase-II-mediated transcription

21 January 2018

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Kin28 is found within TFIIH and a Kin28-Ccl1-Tfb3 trimer complex with differential sensitivities to T-loop phosphorylation

21 January 2018

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DNA topology and a minimal set of basal factors for transcription by RNA polymerase II

21 January 2018

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The KIN28 gene is required both for RNA polymerase II mediated transcription and phosphorylation of the Rpb1p CTD.

21 January 2018

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Impairment of the TFIIH-associated CDK-activating kinase selectively affects cell cycle-regulated gene expression in fission yeast

21 January 2018

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DNA repair gene RAD3 of S. cerevisiae is essential for transcription by RNA polymerase II

21 January 2018

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A Role for the TFIIH XPB DNA Helicase in Promoter Escape by RNA Polymerase II

21 January 2018

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12 December 2020

A transcription reinitiation intermediate that is stabilized by activator

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12 December 2020

The F box protein Dsg1/Mdm30 is a transcriptional coactivator that stimulates Gal4 turnover and cotranscriptional mRNA processing

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12 December 2020

Distinct roles for the helicases of TFIIH in transcript initiation and promoter escape

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0611505104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17392431%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

0 references

1 reference

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28 December 2019

1 reference