eIF4E--from translation to transformation (Q35750110)

10 August 2017

eIF4E--from translation to transformation (English)

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10 August 2017

6

Nahum Sonenberg

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10 August 2017

Yaël Mamane

1

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10 August 2017

Emmanuel Petroulakis

2

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10 August 2017

Liwei Rong

3

1 reference

10 August 2017

Kaori Yoshida

4

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10 August 2017

Lian Wee Ler

5

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10 August 2017

language of work or name

English

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publication date

1 April 2004

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10 August 2017

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10 August 2017

23

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10 August 2017

3172-3179

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10 August 2017

18

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1207549

10 August 2017

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cites work

Translation initiation factor eIF-4G is immunogenic, overexpressed, and amplified in patients with squamous cell lung carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

A mammalian protein targeted by G1-arresting rapamycin-receptor complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Differential expression of Myc1 and Myc2 isoforms in cells transformed by eIF4E: evidence for internal ribosome repositioning in the human c-myc 5'UTR.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Translational control: the cancer connection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Translational regulation in development.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Cyclin-dependent kinase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Differential efficiencies of in vitro translation of mouse c-myc transcripts differing in the 5' untranslated region

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Clinical aspects of cell death in breast cancer: the polyamine pathway as a new target for treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

eIF4E expression in tumors: its possible role in progression of malignancies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Overexpression of eukaryotic protein synthesis initiation factor 4E in HeLa cells results in aberrant growth and morphology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Antisense RNA to eIF4E suppresses oncogenic properties of a head and neck squamous cell carcinoma cell line.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Translational control of the proteome: relevance to cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Dynamic and tissue-specific expression of eIF4E during zebrafish embryogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Mechanisms of c-myc-mediated transcriptional repression of growth arrest genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Translation of ODC mRNA and polyamine transport are suppressed in ras-transformed CREF cells by depleting translation initiation factor 4E.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Translational control and metastatic progression: enhanced activity of the mRNA cap-binding protein eIF-4E selectively enhances translation of metastasis-related mRNAs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Frequent overexpression of cyclin D1 in sporadic pancreatic endocrine tumours

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Internal ribosome initiation of translation and the control of cell death.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

TSC2 mediates cellular energy response to control cell growth and survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Tor signalling in bugs, brain and brawn

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Cyclins and cell cycle checkpoints

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Protein synthesis initiation factor 4G.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Induction of mesoderm in Xenopus laevis embryos by translation initiation factor 4E

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

The promyelocytic leukemia (PML) protein suppresses cyclin D1 protein production by altering the nuclear cytoplasmic distribution of cyclin D1 mRNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Prospective study of eukaryotic initiation factor 4E protein elevation and breast cancer outcome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Translational control of cell fate: availability of phosphorylation sites on translational repressor 4E-BP1 governs its proapoptotic potency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Translation factor eIF4E rescues cells from Myc-dependent apoptosis by inhibiting cytochrome c release.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Model for the regulation of mRNA translation applied to haemoglobin synthesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Activated eIF4E-binding Protein Slows G1 Progression and Blocks Transformation by c-myc without Inhibiting Cell Growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Tumstatin, an endothelial cell-specific inhibitor of protein synthesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

RAS oncogenes: the first 30 years.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Expression and disruption of the Arabidopsis TOR (target of rapamycin) gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Mammalian target of rapamycin: a new molecular target for breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Myc's Mastery of Mitochondrial Mischief

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Expression of eIF4E during head and neck tumorigenesis: possible role in angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

The many faces of c-MYC.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Oncogenes in melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Translational control of the antiapoptotic function of Ras.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

4E-BP3, a new member of the eukaryotic initiation factor 4E-binding protein family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Signal transduction: putting translation before transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Control of the translational machinery in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Cell-cycle-dependent translational control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

The target of rapamycin (TOR) proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Angiogenesis and anti-angiogenesis in hematological malignancies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Upregulation of protein synthesis initiation factor eIF-4E is an early event during colon carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Expression of eukaryotic translation initiation factors 4E and 2alpha is increased frequently in bronchioloalveolar but not in squamous cell carcinomas of the lung

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Eukaryotic translation initiation factor 4E regulates expression of cyclin D1 at transcriptional and post-transcriptional levels

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Increased expression of eukaryotic translation initiation factors eIF-4E and eIF-2 alpha in response to growth induction by c-myc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Does the ribosome translate cancer?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Activation of the c-myc gene by translocation: a model for translational control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Distribution patterns of ornithine decarboxylase in cells and tissues: facts, problems, and postulates.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

TOR, a central controller of cell growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Translational regulation of ornithine decarboxylase and other enzymes of the polyamine pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Angiogenesis inhibitors in the treatment of lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Vascular endothelial cell growth factor (VEGF), an emerging target for cancer chemotherapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Angiogenesis, lymphangiogenesis, and melanoma metastasis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Inhibition of Myc-dependent apoptosis by eukaryotic translation initiation factor 4E requires cyclin D1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Polyamine metabolism and cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Not just for housekeeping: protein initiation and elongation factors in cell growth and tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Molecular basis of angiogenesis and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Expression of eukaryotic translation initiation factors 4E and 2alpha correlates with the progression of thyroid carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Translation initiation and its deregulation during tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

General aspects of anti-angiogenesis and cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207549

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207549

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/l76t5cbckfeyjfauxraudu6cza

30 July 2022

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Dimensions Publication ID

1033137600

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Fatcat ID

release_l76t5cbckfeyjfauxraudu6cza

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Fatcat

https://api.fatcat.wiki/v0/release/l76t5cbckfeyjfauxraudu6cza

30 July 2022

mapped directly with Wikidata item

1 reference

https://api.fatcat.wiki/v0/release/l76t5cbckfeyjfauxraudu6cza

30 July 2022