Atorvastatin treatment is effective when used in combination with mefloquine in an experimental cerebral malaria murine model (Q35753471)

10 August 2017

Atorvastatin treatment is effective when used in combination with mefloquine in an experimental cerebral malaria murine model (English)

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10 August 2017

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Bruno Pradines

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10 August 2017

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Christophe Rogier

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10 August 2017

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Sébastien Briolant

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10 August 2017

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Joel Mosnier

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10 August 2017

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Rémy Amalvict

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10 August 2017

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Eric Baret

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10 August 2017

Jean-Baptiste Souraud

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Jean-Baptiste Souraud

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10 August 2017

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Hélène Savini

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10 August 2017

Jérome Dormoi

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10 August 2017

Raoulin Soulard

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10 August 2017

10 January 2012

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10 August 2017

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https://scigraph.springernature.com/pub.10.1186/1475-2875-11-13

10 August 2017

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cites work

Atorvastatin prevents Plasmodium falciparum cytoadherence and endothelial damage

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Atorvastatin as a potential anti-malarial drug: in vitro synergy in combinational therapy with quinine against Plasmodium falciparum

2 October 2017

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Artemisinin Resistance in Plasmodium falciparum Malaria

2 October 2017

1 reference

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Statins inhibit NK-cell cytotoxicity by interfering with LFA-1-mediated conjugate formation.

2 October 2017

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Statins for sepsis: a critical and updated review

2 October 2017

1 reference

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Diagnosis and management of the neurological complications of falciparum malaria

2 October 2017

1 reference

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Challenges in the determination of early predictors of cerebral malaria: lessons from the human disease and the experimental murine models

2 October 2017

1 reference

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The pleiotropic effects of statins on endothelial function, vascular inflammation, immunomodulation and thrombogenesis

2 October 2017

1 reference

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Cerebral malaria in children is associated with long-term cognitive impairment

2 October 2017

1 reference

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Gene expression analysis reveals early changes in several molecular pathways in cerebral malaria-susceptible mice versus cerebral malaria-resistant mice

2 October 2017

1 reference

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Statins and sepsis: multiple modifications at multiple levels.

2 October 2017

1 reference

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Adjuvant therapy in cerebral malaria

2 October 2017

1 reference

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A unified hypothesis for the genesis of cerebral malaria: sequestration, inflammation and hemostasis leading to microcirculatory dysfunction.

2 October 2017

1 reference

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Pathogenic T cells in cerebral malaria

2 October 2017

1 reference

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Conquering the intolerable burden of malaria: what's new, what's needed: a summary.

2 October 2017

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Pathogenesis of malaria and clinically similar conditions

2 October 2017

1 reference

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Simvastatin decreases nitric oxide overproduction and reverts the impaired vascular responsiveness induced by endotoxic shock in rats

2 October 2017

1 reference

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Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278339

3-hydroxy-3-methylglutaryl coenzyme A reductase-independent inhibition of CD40 expression by atorvastatin in human endothelial cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278339

Diverse effects of inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase on the expression of VCAM-1 and E-selectin in endothelial cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278339

Pathogenesis of cerebral malaria: recent experimental data and possible applications for humans

2 October 2017

1 reference

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Evidence for multiple pathologic and protective mechanisms of murine cerebral malaria.

2 October 2017

1 reference

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Atorvastatin is a promising partner for antimalarial drugs in treatment of Plasmodium falciparum malaria

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278339

Atorvastatin is 10-fold more active in vitro than other statins against Plasmodium falciparum

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278339

HMG-CoA reductase inhibitors inhibit inducible nitric oxide synthase gene expression in macrophages

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278339

Statins (HMG-CoA reductase inhibitors) reduce CD40 expression in human vascular cells

12 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-11-13

Simvastatin reduces the expression of adhesion molecules in circulating monocytes from hypercholesterolemic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-11-13

Statin treatment after onset of sepsis in a murine model improves survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-11-13

HMG-CoA reductase inhibitors improve acute ischemic stroke outcome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-11-13

Simvastatin treatment shows no effect on the incidence of cerebral malaria or parasitemia during experimental malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-11-13

Synergy of mefloquine activity with atorvastatin, but not chloroquine and monodesethylamodiaquine, and association with the pfmdr1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-11-13

Atorvastatin as a potential antimalarial drug: in vitro synergy in combinational therapy with dihydroartemisinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-11-13

Behavioural and histopathological alterations in mice with cerebral malaria.

21 January 2018

1 reference

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Statins alone are ineffective in cerebral malaria but potentiate artesunate

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-11-13

Statins fail to improve outcome in experimental cerebral malaria and potentiate Toll-like receptor-mediated cytokine production by murine macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-11-13

Plasmodium berghei: cerebral malaria in CBA mice is not clearly related to plasma TNF levels or intensity of histopathological changes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-11-13

Neuronal apoptosis, metallothionein expression and proinflammatory responses during cerebral malaria in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-11-13

NK cells stimulate recruitment of CXCR3+ T cells to the brain during Plasmodium berghei-mediated cerebral malaria.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278339

Perforin-dependent brain-infiltrating cytotoxic CD8+ T lymphocytes mediate experimental cerebral malaria pathogenesis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278339

Cerivastatin improves survival of mice with lipopolysaccharide-induced sepsis

25 September 2018

1 reference

12 December 2020

Statins as a newly recognized type of immunomodulator

1 reference

12 December 2020

Pravastatin down-regulates inflammatory mediators in human monocytes in vitro

1 reference

12 December 2020

Validated HPLC-MS-MS method for simultaneous determination of atorvastatin and 2-hydroxyatorvastatin in human plasma-pharmacokinetic study

1 reference

12 December 2020

Identifiers

DOI

10.1186/1475-2875-11-13

1 reference

Dimensions Publication ID

10 August 2017

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1 reference

10 August 2017

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