Tumor galectinology: insights into the complex network of a family of endogenous lectins (Q35759425)

10 August 2017

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title

Tumor galectinology: insights into the complex network of a family of endogenous lectins (English)

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10 August 2017

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Andreas Hoeflich

3

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Herbert Kaltner

Herbert Kaltner

4

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Sabine André

Sabine André

2

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Eckhard Wolf

Eckhard Wolf

8

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Hans-Joachim Gabius

Hans-Joachim Gabius

9

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author name string

Harald Lahm

1

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10 August 2017

Hans-Christian Siebert

5

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10 August 2017

Bernard Sordat

6

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10 August 2017

Claus-Wilhelm von der Lieth

7

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10 August 2017

1 January 2004

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10 August 2017

Glycoconjugate Journal

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10 August 2017

20

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10 August 2017

4

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10 August 2017

227-238

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https://scigraph.springernature.com/pub.10.1023/b:glyc.0000025817.24297.17

10 August 2017

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Galectin-8 expression decreases in cancer compared with normal and dysplastic human colon tissue and acts significantly on human colon cancer cell migration as a suppressor

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Blood group antigen A and flow cytometric analysis in resected early-stage non-small cell lung cancer

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Galectin-1 Augments Ras Activation and Diverts Ras Signals to Raf-1 at the Expense of Phosphoinositide 3-Kinase

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MEC1 and MEC2: two new cell lines derived from B-chronic lymphocytic leukaemia in prolymphocytoid transformation

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Principles of structures of animal and plant lectins

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Differential gene expression profiles of scirrhous gastric cancer cells with high metastatic potential to peritoneum or lymph nodes.

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Expression of Po66-CBP, a type-8 galectin, in different healthy, tumoral and peritumoral tissues

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Correlation of expression of binding sites for synthetic blood group A-, B- and H-trisaccharides and for sarcolectin with survival of patients with bronchial carcinoma.

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Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

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Galectin-1 binds oncogenic H-Ras to mediate Ras membrane anchorage and cell transformation

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Eukaryotic glycosylation: whim of nature or multipurpose tool?

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Beta-1,4-galactosylation of N-glycans is a complex process

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Extracellular tyrosinase mRNA within apoptotic bodies is protected from degradation in human serum

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Cell surface glycolipids and glycoproteins in malignant transformation.

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Comparison of blocked and non-blocked ricin-antibody immunotoxins against human gastric carcinoma and colorectal adenocarcinoma cell lines.

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New alternatively spliced form of galectin-3, a member of the beta-galactoside-binding animal lectin family, contains a predicted transmembrane-spanning domain and a leucine zipper motif

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Intracellular functions of galectins

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Natural autoantibody to galectin-9 in normal human sera

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Animal lectins: a historical introduction and overview

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Lectin cytochemistry and histochemistry

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Human ecalectin, a variant of human galectin-9, is a novel eosinophil chemoattractant produced by T lymphocytes

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Purification of a tumoral marker recognized by monoclonal antibody Po66 and associated with human lung squamous cell carcinoma.

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Involvement of laser photo-CIDNP (chemically induced dynamic nuclear polarization)-reactive amino acid side chains in ligand binding by galactoside-specific lectins in solution.

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Pattern of endogenous lectins in a human epithelial tumor

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Cloning of a second dendritic cell-associated C-type lectin (dectin-2) and its alternatively spliced isoforms

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Galectins: multipurpose carbohydrate-binding proteins implicated in tumor biology

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Rigidified multivalent lactose molecules and their interactions with mammalian galectins: a route to selective inhibitors.

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Expression of galectin-1 mRNA correlates with the malignant potential of human gliomas and expression of antisense galectin-1 inhibits the growth of 9 glioma cells.

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Concepts of tumor lectinology

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12 December 2020

Lactose-containing starburst dendrimers: influence of dendrimer generation and binding-site orientation of receptors (plant/animal lectins and immunoglobulins) on binding properties

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12 December 2020

Establishment, characterization and determination of cell surface sugar receptor (lectin) expression by neoglycoenzymes of a human myeloid marker-expressing B lymphoblastoid cell line

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12 December 2020

Endogenous tumor lectins: a new class of tumor markers and targets for therapy?

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Medicinal Chemistry Based on the Sugar Code: Fundamentals of Lectinology and Experimental Strategies with Lectins as Targets

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12 December 2020

Low micromolar inhibitors of galectin-3 based on 3'-derivatization of N-acetyllactosamine

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Glycoprotein glycosylation and cancer progression

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12 December 2020

Role of galectins in inflammatory and immunomodulatory processes

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12 December 2020

Establishment of a leukemic cell model for studying human pre-B to B cell differentiation.

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12 December 2020

Animal lectins as cell adhesion molecules

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12 December 2020

Carbohydrate-binding proteins in cancer, and their ligands as therapeutic agents.

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Heparin binding lectin of human placenta as a tool for histochemical ligand localization and isolation

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12 December 2020

Malignant cell glycoproteins and glycolipids

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12 December 2020

Lectin-mediated drug targeting: selection of valency, sugar type (Gal/Lac), and spacer length for cluster glycosides as parameters to distinguish ligand binding to C-type asialoglycoprotein receptors and galectins.

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12 December 2020

A beta-D-galactoside binding protein from electric organ tissue of Electrophorus electricus

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12 December 2020

Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens.

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12 December 2020

Applications of lectins and neoglycoconjugates in histology and pathology

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12 December 2020

Glycolipids of hamster fibroblasts and derived malignant-transformed cell lines

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12 December 2020

Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions

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12 December 2020

Galectin-1 is highly expressed in human gliomas with relevance for modulation of invasion of tumor astrocytes into the brain parenchyma.

1 reference

12 December 2020

Immunohistochemical profile of galectin-8 expression in benign and malignant tumors of epithelial, mesenchymatous and adipous origins, and of the nervous system

1 reference

12 December 2020

The levels of expression of galectin-3, but not of galectin-1 and galectin-8, correlate with apoptosis in human cholesteatomas

1 reference

12 December 2020

Identification of a human homologue of the dendritic cell-associated C-type lectin-1, dectin-1

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12 December 2020

Perspectives on the significance of altered glycosylation of glycoproteins in cancer

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12 December 2020

Localization of endogenous beta-galactoside-specific lectins by neoglycoproteins, lectin-binding tissue glycoproteins and antibodies and of accessible lectin-specific ligands by mammalian lectin in human breast carcinomas

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12 December 2020

Galectin-8 binding to integrins inhibits cell adhesion and induces apoptosis

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12 December 2020

Lectin ligands: new insights into their conformations and their dynamic behavior and the discovery of conformer selection by lectins

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12 December 2020

Cancer-associated glycosphingolipid antigens: their structure, organization, and function

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12 December 2020

Galectin-1 modulates human glioblastoma cell migration into the brain through modifications to the actin cytoskeleton and levels of expression of small GTPases.

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12 December 2020

Molecular definition of a novel human galectin which is immunogenic in patients with Hodgkin's disease

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12 December 2020

Peptides and growth factors in small cell lung cancer: production, binding sites, and growth effects

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12 December 2020

Galectinomics: finding themes in complexity

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12 December 2020

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12 December 2020

Immunohistochemical expression of the intracellular component of galectin-8 in squamous cell metaplasia of the bronchial epithelium in neoplastic and benign processes

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12 December 2020

Expression of p64c-myc and neuroendocrine properties define three subclasses of small cell lung cancer

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12 December 2020

The sugar code: functional lectinomics

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12 December 2020

Galectin-8: a complex sub-family of galectins (Review)

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12 December 2020

Benign metastasizing leiomyoma of the uterus: documentation of clinical, immunohistochemical and lectin-histochemical data of ten cases

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12 December 2020

Expression of Blood-Group Antigen A — A Favorable Prognostic Factor in Non-Small-Cell Lung Cancer

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12 December 2020

Negative regulation of neuroblastoma cell growth by carbohydrate-dependent surface binding of galectin-1 and functional divergence from galectin-3.

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12 December 2020

Reverse lectin histochemistry: design and application of glycoligands for detection of cell and tissue lectins

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12 December 2020

Two messenger RNAs and five isoforms for Po66-CBP, a galectin-8 homolog in a human lung carcinoma cell line

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12 December 2020

Growth and migration markers of rat C6 glioma cells identified by serial analysis of gene expression

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12 December 2020

Endogenous lectins as targets for drug delivery

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12 December 2020

Expression of Po66-CBP, a galectin-8, in different types of primary and secondary broncho-pulmonary tumors

1 reference

12 December 2020

A new combined computational and NMR-spectroscopical strategy for the identification of additional conformational constraints of the bound ligand in an aprotic solvent

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12 December 2020

A monoclonal antibody (Po66) directed against human lung squamous cell carcinoma immunolocalization of tumour xenografts in nude mice

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12 December 2020

A retrospective and prospective view of glycopathology.

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12 December 2020

Malignant progression of SV40-immortalised human milk epithelial cells

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12 December 2020

Galectin-1 is a major receptor for ganglioside GM1, a product of the growth-controlling activity of a cell surface ganglioside sialidase, on human neuroblastoma cells in culture

1 reference

12 December 2020

Wedgelike glycodendrimers as inhibitors of binding of mammalian galectins to glycoproteins, lactose maxiclusters, and cell surface glycoconjugates

1 reference

12 December 2020

Galectins-1 and -3 and their ligands in tumor biology. Non-uniform properties in cell-surface presentation and modulation of adhesion to matrix glycoproteins for various tumor cell lines, in biodistribution of free and liposome-bound galectins and i

1 reference

12 December 2020

CD4+CD7- leukemic T cells from patients with Sézary syndrome are protected from galectin-1-triggered T cell death.

1 reference

12 December 2020

Triggering of antitumor activity through melanoma-specific transduction of a constitutively active tumor necrosis factor (TNF) R1 chimeric receptor in the absence of TNF-alpha

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12 December 2020

Galectins are differentially expressed in supratentorial pilocytic astrocytomas, astrocytomas, anaplastic astrocytomas and glioblastomas, and significantly modulate tumor astrocyte migration.

1 reference

12 December 2020

Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin.

1 reference

12 December 2020

Cloning of human DECTIN-1, a novel C-type lectin-like receptor gene expressed on dendritic cells

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12 December 2020

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12 December 2020

Differential display cloning identifies motility-related protein (MRP1/CD9) as highly expressed in primary compared to metastatic human colon carcinoma cells

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12 December 2020

Galectin-8 functions as a matricellular modulator of cell adhesion

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12 December 2020

Glycoproteins and their relationship to human disease

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12 December 2020

The use of lectins in histopathology

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12 December 2020

Cell surface carbohydrates as prognostic markers in human carcinomas

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12 December 2020

Terminal glycosylation and disease: influence on cancer and cystic fibrosis

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12 December 2020

Gene expression of galectin-9/ecalectin, a potent eosinophil chemoattractant, and/or the insertional isoform in human colorectal carcinoma cell lines and detection of frame-shift mutations for protein sequence truncations in the second functional lec

1 reference

12 December 2020

Surface-epitope masking and expression cloning identifies the human prostate carcinoma tumor antigen gene PCTA-1 a member of the galectin gene family

1 reference

12 December 2020

10.1023/B:GLYC.0000025817.24297.17

Identifiers

DOI

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Dimensions Publication ID

10 August 2017

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