Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast (Q35763361)

10 August 2017

title

Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast (English)

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10 August 2017

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21

Susan Lindquist

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10 August 2017

15

David A Bennett

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10 August 2017

13

Eric M Reiman

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10 August 2017

18

Rudolph E Tanzi

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10 August 2017

14

Denis A Evans

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10 August 2017

Sebastian Treusch

1

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10 August 2017

Shusei Hamamichi

2

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10 August 2017

Jessica L Goodman

3

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10 August 2017

Kent E S Matlack

4

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10 August 2017

Chee Yeun Chung

5

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10 August 2017

Valeriya Baru

6

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10 August 2017

Joshua M Shulman

7

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10 August 2017

Antonio Parrado

8

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10 August 2017

Brooke J Bevis

9

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10 August 2017

Julie S Valastyan

10

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10 August 2017

Haesun Han

11

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10 August 2017

Malin Lindhagen-Persson

12

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10 August 2017

Anders Olofsson

16

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10 August 2017

Philip L DeJager

17

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10 August 2017

Kim A Caldwell

19

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10 August 2017

Guy A Caldwell

20

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10 August 2017

language of work or name

English

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publication date

27 October 2011

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10 August 2017

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10 August 2017

volume

334

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10 August 2017

issue

6060

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10 August 2017

page(s)

1241-1245

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Directed conversion of Alzheimer's disease patient skin fibroblasts into functional neurons

10 August 2017

cites work

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Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

2 October 2017

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Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

2 October 2017

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Intermediate phenotypes identify divergent pathways to Alzheimer's disease

2 October 2017

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Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models

2 October 2017

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2 October 2017

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Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

2 October 2017

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Neuropathologic intermediate phenotypes enhance association to Alzheimer susceptibility alleles

2 October 2017

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Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

2 October 2017

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Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE.

2 October 2017

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Amyloid precursor protein trafficking, processing, and function

2 October 2017

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Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

2 October 2017

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Interaction between Epsin/Yap180 adaptors and the scaffolds Ede1/Pan1 is required for endocytosis

2 October 2017

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Presenilin: running with scissors in the membrane

2 October 2017

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Structure and function analysis of the CMS/CIN85 protein family identifies actin-bundling properties and heterotypic-complex formation.

2 October 2017

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Clathrin-mediated endocytosis at synapses

2 October 2017

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Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

2 October 2017

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PtdIns(4,5)P2 turnover is required for multiple stages during clathrin- and actin-dependent endocytic internalization

2 October 2017

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Intracellular Abeta and cognitive deficits precede beta-amyloid deposition in transgenic arcAbeta mice

2 October 2017

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Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

2 October 2017

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Amyloid beta-peptide interactions with neuronal and glial cell plasma membrane: binding sites and implications for Alzheimer's disease

2 October 2017

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The Rsp5 ubiquitin ligase binds to and ubiquitinates members of the yeast CIN85-endophilin complex, Sla1-Rvs167.

2 October 2017

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2 October 2017

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2 October 2017

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Secretion efficiency in Saccharomyces cerevisiae of bovine pancreatic trypsin inhibitor mutants lacking disulfide bonds is correlated with thermodynamic stability

2 October 2017

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2 October 2017

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2 October 2017

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25 September 2018

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Yeast cells provide insight into alpha-synuclein biology and pathobiology

25 September 2018

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25 September 2018

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25 September 2018

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25 September 2018

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Construction, verification and experimental use of two epitope-tagged collections of budding yeast strains

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Hypothesis-based RNAi screening identifies neuroprotective genes in a Parkinson's disease model

21 January 2018

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Long-term culture of mouse cortical neurons as a model for neuronal development, aging, and death

21 January 2018

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CR1 is associated with amyloid plaque burden and age-related cognitive decline

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22033521

inferred from PubMed ID database lookup

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based on heuristic

The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain

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PubMed

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inferred from PubMed ID database lookup

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Identifiers

DOI

10.1126/SCIENCE.1213210

1 reference

10 August 2017

1 reference

10 August 2017

1 reference