Leucine-rich repeat kinase 2 deficiency is protective in rhabdomyolysis-induced kidney injury. (Q35766417)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25904107%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

Leucine-rich repeat kinase 2 deficiency is protective in rhabdomyolysis-induced kidney injury (English)

1 reference

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6 March 2020

1 reference

2

1 reference

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6 March 2020

Mark S Moehle

5

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6 March 2020

Andrew B. West

12

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6 March 2020

author name string

Ravindra Boddu

1

1 reference

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6 March 2020

Subhashini Bolisetty

3

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6 March 2020

Xianzhen Hu

4

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6 March 2020

João Paulo Lima Daher

6

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6 March 2020

Ahmed Ibrahim Kamal

7

1 reference

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6 March 2020

Reny Joseph

8

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6 March 2020

James F George

9

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6 March 2020

Anupam Agarwal

10

1 reference

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6 March 2020

Lisa M Curtis

11

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6 March 2020

publication date

22 April 2015

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6 March 2020

published in

Human Molecular Genetics

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6 March 2020

volume

24

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6 March 2020

issue

14

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6 March 2020

page(s)

4078-4093

1 reference

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M1 and M2 immune activation in Parkinson's Disease: Foe and ally?

6 March 2020

cites work

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Specific macrophage subtypes influence the progression of rhabdomyolysis-induced kidney injury

2 October 2017

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Leucine-rich repeat kinase 2 (LRRK2)-deficient rats exhibit renal tubule injury and perturbations in metabolic and immunological homeostasis

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Heme oxygenase-1 expression protects the heart from acute injury caused by inducible Cre recombinase.

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Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies

2 October 2017

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LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors

2 October 2017

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Parkinson's disease and immune system: is the culprit LRRKing in the periphery?

2 October 2017

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Impaired inflammatory responses in murine Lrrk2-knockdown brain microglia

2 October 2017

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In vivo regulation of the heme oxygenase-1 gene in humanized transgenic mice

2 October 2017

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2 October 2017

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LRRK2 inhibition attenuates microglial inflammatory responses

2 October 2017

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Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway

2 October 2017

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The renal mononuclear phagocytic system

2 October 2017

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Transcriptional responses to loss or gain of function of the leucine-rich repeat kinase 2 (LRRK2) gene uncover biological processes modulated by LRRK2 activity

2 October 2017

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2 October 2017

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2 October 2017

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LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice

2 October 2017

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2 October 2017

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Autophosphorylation in the leucine-rich repeat kinase 2 (LRRK2) GTPase domain modifies kinase and GTP-binding activities

2 October 2017

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Regulation of LRRK2 expression points to a functional role in human monocyte maturation

2 October 2017

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A two-stage meta-analysis identifies several new loci for Parkinson's disease

2 October 2017

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Essential role of factor B of the alternative complement pathway in complement activation and opsonophagocytosis during acute pneumococcal otitis media in mice

2 October 2017

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2 October 2017

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The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease

2 October 2017

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Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of alpha-synuclein, and apoptotic cell death in aged mice

2 October 2017

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Acetaminophen inhibits hemoprotein-catalyzed lipid peroxidation and attenuates rhabdomyolysis-induced renal failure

2 October 2017

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2 October 2017

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2 October 2017

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Genome-wide association study reveals genetic risk underlying Parkinson's disease

2 October 2017

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Dependence of leucine-rich repeat kinase 2 (LRRK2) kinase activity on dimerization

2 October 2017

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Heme oxygenase-1 affords protection against noncerebral forms of severe malaria

2 October 2017

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2 October 2017

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MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Lipofuscin: mechanisms of age-related accumulation and influence on cell function

2 October 2017

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2 October 2017

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2 October 2017

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Induction of heme oxygenase is a rapid, protective response in rhabdomyolysis in the rat

2 October 2017

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Spectral differences between the alpha and beta heme groups within human deoxyhemoglobin

2 October 2017

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LRRK2 secretion in exosomes is regulated by 14-3-3.

2 October 2017

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Dissociation of local nitric oxide concentration and vasoconstriction in the presence of cell-free hemoglobin oxygen carriers

27 July 2018

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Pitfalls using metalloporphyrins in carbon monoxide research

27 July 2018

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Effect of selective LRRK2 kinase inhibition on nonhuman primate lung.

27 July 2018

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Macrophage depletion ameliorates glycerol-induced acute kidney injury in mice.

25 September 2018

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Ser1292 autophosphorylation is an indicator of LRRK2 kinase activity and contributes to the cellular effects of PD mutations

25 September 2018

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LRRK2 kinase activity mediates toxic interactions between genetic mutation and oxidative stress in a Drosophila model: suppression by curcumin

25 September 2018

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LRRK2 enhances oxidative stress-induced neurotoxicity via its kinase activity

25 September 2018

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25 September 2018

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Macrophages contribute to the initiation of ischaemic acute renal failure in rats

25 September 2018

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Comparison of label-free methods for quantifying human proteins by shotgun proteomics.

25 September 2018

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Epithelial cells and expression of the phagocytic marker CD68: scavenging of apoptotic bodies following Rho activation.

25 September 2018

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Effect of heme oxygenase inhibitors on soluble guanylyl cyclase activity

25 September 2018

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Increased hippocampal CA1 density of serotonergic terminals in a triple transgenic mouse model of Alzheimer's disease: an ultrastructural study

25 September 2018

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Crossref

https://api.crossref.org/works/10.1093%2FHMG%2FDDV147

The Parkinson disease gene LRRK2: evolutionary and structural insights

21 January 2018

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12 December 2020

CD163-Mediated hemoglobin-heme uptake activates macrophage HO-1, providing an antiinflammatory function

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12 December 2020

Absorption spectra of human fetal and adult oxyhemoglobin, de-oxyhemoglobin, carboxyhemoglobin, and methemoglobin

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12 December 2020

The acute phase response

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12 December 2020

[Quantitative determination of hemoglobin, oxyhemoglobin, carbon oxide hemoglobin and metahemoglobin in small blood specimens by means of spectrophotometry]

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12 December 2020

Identifiers

DOI

10.1093/HMG/DDV147

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25904107%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25904107%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

PubMed publication ID

25904107

1 reference