Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid (Q35768692)

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scholarly article

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English	Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid	scholarly article

Statements

scholarly article

1 reference

Europe PubMed Central

10 August 2017

Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid (English)

1 reference

Europe PubMed Central

10 August 2017

macular degeneration

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

P T Johnson

1

1 reference

Europe PubMed Central

10 August 2017

K E Betts

2

1 reference

Europe PubMed Central

10 August 2017

M J Radeke

3

1 reference

Europe PubMed Central

10 August 2017

G S Hageman

4

1 reference

Europe PubMed Central

10 August 2017

D H Anderson

5

1 reference

Europe PubMed Central

10 August 2017

L V Johnson

6

1 reference

Europe PubMed Central

10 August 2017

language of work or name

0 references

publication date

1 November 2006

1 reference

Europe PubMed Central

10 August 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

10 August 2017

103

1 reference

Europe PubMed Central

10 August 2017

17456-17461

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Europe PubMed Central

10 August 2017

46

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Europe PubMed Central

10 August 2017

CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

Complement factor H polymorphism, complement activators, and risk of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

A prospective assessment of the Y402H variant in complement factor H, genetic variants in C-reactive protein, and risk of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

The role of inflammation in the pathogenesis of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

Synaptic pathology, altered gene expression, and degeneration in photoreceptors impacted by drusen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

An interactive web database of factor H-associated hemolytic uremic syndrome mutations: insights into the structural consequences of disease-associated mutations

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

Association of common CRP gene variants with CRP levels and cardiovascular events.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

The relation between C reactive protein and age related macular degeneration in the Cardiovascular Health Study

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

Complement factor H polymorphism in age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

Complement factor H polymorphism and age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

Complement factor H variant increases the risk of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

C-reactive Protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

The human complement factor H: functional roles, genetic variations and disease associations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

The epidemiology of age-related macular degeneration

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

Epidemiology of age-related maculopathy: a review

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

Markers of inflammation and cardiovascular disease: application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

Factor H family proteins: on complement, microbes and human diseases

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

https://api.crossref.org/works/10.1073%2FPNAS.0606234103

21 January 2018

Serum amyloid P component and C-reactive protein opsonize apoptotic cells for phagocytosis through Fcgamma receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

Drusen proteome analysis: an approach to the etiology of age-related macular degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

C-reactive protein-mediated phagocytosis and phospholipase D signalling through the high-affinity receptor for immunoglobulin G (FcgammaRI).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

A role for local inflammation in the formation of drusen in the aging eye.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

1 reference

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12 July 2018

Complement activation and inflammatory processes in Drusen formation and age related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

Local cellular sources of apolipoprotein E in the human retina and retinal pigmented epithelium: implications for the process of drusen formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

Multiple ligand binding sites on domain seven of human complement factor H.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

C-Reactive protein binds to apoptotic cells, protects the cells from assembly of the terminal complement components, and sustains an antiinflammatory innate immune response: implications for systemic autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

Inflammation and Alzheimer's disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

Regulation of complement activation by C-reactive protein: targeting the complement inhibitory activity of factor H by an interaction with short consensus repeat domains 7 and 8-11.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

The major receptor for C-reactive protein on leukocytes is fcgamma receptor II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

Specificity of C-reactive protein for choline phosphate residues of pneumococcal C-polysaccharide.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859950

12 July 2018

Interaction of C-reactive protein complexes with the complement system. II. Consumption of guinea pig complement by CRP complexes: requirement for human C1q.

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12 July 2018

C-reactive protein receptors on the human monocytic cell line U-937. Evidence for additional binding to Fc gamma RI.

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12 July 2018

A potential role for immune complex pathogenesis in drusen formation

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21 January 2018

Association between C-reactive protein and age-related macular degeneration.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0606234103

21 January 2018

Progression of age-related macular degeneration: prospective assessment of C-reactive protein, interleukin 6, and other cardiovascular biomarkers.

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https://api.crossref.org/works/10.1073%2FPNAS.0606234103

21 January 2018

C-reactive protein and homocysteine are associated with dietary and behavioral risk factors for age-related macular degeneration.

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https://api.crossref.org/works/10.1073%2FPNAS.0606234103

21 January 2018

Biomarkers of cardiovascular disease as risk factors for age-related macular degeneration

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https://api.crossref.org/works/10.1073%2FPNAS.0606234103

21 January 2018

Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice

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https://api.crossref.org/works/10.1073%2FPNAS.0606234103

21 January 2018

Demonstration of CRP immunoreactivity in brains of Alzheimer's disease: immunohistochemical study using formic acid pretreatment of tissue sections.

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https://api.crossref.org/works/10.1073%2FPNAS.0606234103

21 January 2018

C-reactive protein increases matrix metalloproteinase-2 expression and activity in cultured human vascular smooth muscle cells.

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21 January 2018

His-384 Allotypic Variant of Factor H Associated with Age-related Macular Degeneration Has Different Heparin Binding Properties from the Non-disease-associated Form

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https://api.crossref.org/works/10.1073%2FPNAS.0606234103

21 January 2018

Inflammatory markers in age-related maculopathy: cross-sectional analysis from the Muenster Aging and Retina Study

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https://pubmed.ncbi.nlm.nih.gov/17079491

12 December 2020

based on heuristic

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Direct proinflammatory effect of C-reactive protein on human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17079491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C-reactive protein stimulates MMP-1 expression in U937 histiocytes through Fc[gamma]RII and extracellular signal-regulated kinase pathway:: an implication of CRP involvement in plaque destabilization

1 reference

https://pubmed.ncbi.nlm.nih.gov/17079491

12 December 2020

based on heuristic

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Binding of C-reactive protein to chromatin and nucleosome core particles. A possible physiological role of C-reactive protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17079491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C-reactive protein immunohistochemical localization in normal and atherosclerotic human aortas

1 reference

https://pubmed.ncbi.nlm.nih.gov/17079491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitronectin is a constituent of ocular drusen and the vitronectin gene is expressed in human retinal pigmented epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17079491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.0606234103

1 reference

Europe PubMed Central

10 August 2017

2006PNAS..10317456J

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1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

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