CD49d expression is an independent predictor of overall survival in patients with chronic lymphocytic leukaemia: a prognostic parameter with therapeutic potential (Q35769292)

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scientific article published on March 2008

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English	CD49d expression is an independent predictor of overall survival in patients with chronic lymphocytic leukaemia: a prognostic parameter with therapeutic potential	scientific article published on March 2008

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scholarly article

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Europe PubMed Central

PubMed publication ID

10 August 2017

CD49d expression is an independent predictor of overall survival in patients with chronic lymphocytic leukaemia: a prognostic parameter with therapeutic potential (English)

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Europe PubMed Central

PubMed publication ID

10 August 2017

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Tait D Shanafelt

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Tait D Shanafelt

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10 August 2017

Timothy G. Call

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Tim G Call

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Clive S Zent

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Diane F. Jelinek

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Diane F Jelinek

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Neil E Kay

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Renee C. Tschumper

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Renee C Tschumper

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Susan Michelle Geyer

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Susan M Geyer

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10 August 2017

Gordon W Dewald

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Gordon W Dewald

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10 August 2017

Betsy R LaPlant

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Betsy Laplant

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10 August 2017

author name string

Nancy D Bone

3

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Tom E Witzig

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Greg S Nowakowski

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publication date

1 March 2008

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British Journal of Haematology

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10 August 2017

140

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10 August 2017

5

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Europe PubMed Central

PubMed publication ID

10 August 2017

537-546

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Europe PubMed Central

PubMed publication ID

10 August 2017

Bone biopsy derived marrow stromal elements rescue chronic lymphocytic leukemia B-cells from spontaneous and drug induced cell death and facilitates an "angiogenic switch".

1 reference

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Involvement of p53 in alpha4beta1 integrin-mediated resistance of B-CLL cells to fludarabine.

1 reference

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Role of the microenvironment in chronic lymphocytic leukaemia

1 reference

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Prognosis at diagnosis: integrating molecular biologic insights into clinical practice for patients with CLL

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1 reference

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Chronic B cell malignancies and bone marrow microenvironment

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The chemokine receptor CCR7 and alpha4 integrin are important for migration of chronic lymphocytic leukemia cells into lymph nodes

1 reference

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Engagement of alpha4beta1 integrin by fibronectin induces in vitro resistance of B chronic lymphocytic leukemia cells to fludarabine

1 reference

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CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease.

1 reference

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Genomic aberrations and survival in chronic lymphocytic leukemia

1 reference

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Rheumatoid arthritis synovial stromal cells inhibit apoptosis and up-regulate Bcl-xL expression by B cells in a CD49/CD29-CD106-dependent mechanism

1 reference

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27 July 2018

Chronic lymphocytic leukemia B cells express functional CXCR4 chemokine receptors that mediate spontaneous migration beneath bone marrow stromal cells.

1 reference

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The integrin VLA-4 supports tethering and rolling in flow on VCAM-1.

1 reference

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VLA proteins in the integrin family: structures, functions, and their role on leukocytes

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Differential expression of very late activation antigen-3 (VLA-3)/VLA-4 in B-cell non-Hodgkin lymphoma and B-cell chronic lymphocytic leukemia

1 reference

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27 July 2018

Prospective evaluation of clonal evolution during long-term follow-up of patients with untreated early-stage chronic lymphocytic leukemia.

1 reference

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A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis

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25 September 2018

CD38 expression levels in chronic lymphocytic leukemia B cells are associated with activation marker expression and differential responses to interferon stimulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477272

25 September 2018

Signature of B-CLL with different prognosis by Shrunken centroids of surface antigen expression profiling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477272

25 September 2018

ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477272

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ZAP-70 expression and prognosis in chronic lymphocytic leukaemia

1 reference

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ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia.

1 reference

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1 reference

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Expression of ribosomal and translation-associated genes is correlated with a favorable clinical course in chronic lymphocytic leukemia.

1 reference

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Alpha4 integrins and the immune response

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V(H) mutation status, CD38 expression level, genomic aberrations, and survival in chronic lymphocytic leukemia.

1 reference

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1 reference

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Adhesion to bone marrow stroma inhibits apoptosis of chronic lymphocytic leukemia cells.

1 reference

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Adhesion through the LFA-1 (CD11a/CD18)-ICAM-1 (CD54) and the VLA-4 (CD49d)-VCAM-1 (CD106) pathways prevents apoptosis of germinal center B cells.

1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18275431

12 December 2020

based on heuristic

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Human bone marrow stromal cells prevent apoptosis and support the survival of chronic lymphocytic leukaemia cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/18275431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytogenetic abnormalities can change during the course of the disease process in chronic lymphocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18275431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD49d in B-cell chronic lymphocytic leukemia: correlated expression with CD38 and prognostic relevance

1 reference

https://pubmed.ncbi.nlm.nih.gov/18275431

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adhesion receptors on peripheral blood leukemic B cells. A comparative study on B cell chronic lymphocytic leukemia and related lymphoma/leukemias

1 reference

https://pubmed.ncbi.nlm.nih.gov/18275431

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Reduced expression of adhesion molecules and cell signaling receptors by chronic lymphocytic leukemia cells with 11q deletion

1 reference

https://pubmed.ncbi.nlm.nih.gov/18275431

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inferred from PubMed ID database lookup

Differential adhesion pattern of B cell chronic lymphocytic leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18275431

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Integrin function in chronic lymphocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18275431

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based on heuristic

inferred from PubMed ID database lookup

Chronic lymphocytic leukemic B cells but not normal B cells are rescued from apoptosis by contact with normal bone marrow stromal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18275431

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Chromosome anomalies detected by interphase fluorescence in situ hybridization: correlation with significant biological features of B-cell chronic lymphocytic leukaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18275431

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18275431

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Fibronectin interaction with α4β1 integrin prevents apoptosis in B cell chronic lymphocytic leukemia: correlation with Bcl-2 and Bax

1 reference

https://pubmed.ncbi.nlm.nih.gov/18275431

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Expression of adhesion molecules in chronic B-cell lymphoproliferative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/18275431

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Role of beta2 integrins in the prevention of apoptosis induction in chronic lymphocytic leukemia B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18275431

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based on heuristic

inferred from PubMed ID database lookup

Variable expression of CD49d antigen in B cell chronic lymphocytic leukemia is related to disease stages

1 reference

https://pubmed.ncbi.nlm.nih.gov/18275431

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Multivariate analysis of prognostic factors in CLL: clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18275431

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Identifiers

10.1111/J.1365-2141.2007.06965.X

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

ResearchGate publication ID

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