Polygamain, a new microtubule depolymerizing agent that occupies a unique pharmacophore in the colchicine site (Q35776779)

10 August 2017

title

Polygamain, a new microtubule depolymerizing agent that occupies a unique pharmacophore in the colchicine site (English)

1 reference

10 August 2017

1 reference

R M Hartley

1

1 reference

10 August 2017

J Peng

2

1 reference

10 August 2017

G A Fest

3

1 reference

10 August 2017

S Dakshanamurthy

4

1 reference

10 August 2017

D E Frantz

5

1 reference

10 August 2017

M L Brown

6

1 reference

10 August 2017

S L Mooberry

7

1 reference

10 August 2017

language of work or name

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14 December 2011

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10 August 2017

published in

Molecular Pharmacology

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10 August 2017

volume

81

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10 August 2017

issue

3

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10 August 2017

page(s)

431-439

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Synthesis and biological activities of (R)- and (S)-N-(4-Methoxyphenyl)-N,2,6-trimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-aminium chloride as potent cytotoxic antitubulin agents

10 August 2017

cites work

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Promotion of fluorescence upon binding of colchicine to tubulin

12 July 2018

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12 July 2018

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12 July 2018

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Kinetics of colchicine binding to purified beta-tubulin isotypes from bovine brain

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Binding of indanocine to the colchicine site on tubulin promotes fluorescence, and its binding parameters resemble those of the colchicine analogue AC.

25 September 2018

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25 September 2018

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A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach

25 September 2018

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25 September 2018

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25 September 2018

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25 September 2018

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Novel 2-methoxyestradiol analogues with antitumor activity

25 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286304

Predicting chemotherapy response to paclitaxel-based therapy in advanced non-small-cell lung cancer with P-glycoprotein expression.

25 September 2018

1 reference

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Phase I safety, pharmacokinetic and pharmacodynamic studies of 2-methoxyestradiol alone or in combination with docetaxel in patients with locally recurrent or metastatic breast cancer

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22169850

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Antineoplastic agents 322. synthesis of combretastatin A-4 prodrugs

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22169850

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role of chance observations in chemotherapy: Vinca rosea

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22169850

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1124/MOL.111.075838

1 reference

10 August 2017

1 reference

10 August 2017

1 reference