hMLH1 promoter hypermethylation in microsatellite instability-positive endometrial carcinoma. Cause or consequence? (Q35788174)

10 August 2017

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hMLH1 promoter hypermethylation in microsatellite instability-positive endometrial carcinoma. Cause or consequence? (English)

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10 August 2017

1 reference

1 reference

L H Ellenson

1

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PubMed ID

10550292

10 August 2017

language of work or name

English

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publication date

1 November 1999

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The American Journal of Pathology

10 August 2017

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10 August 2017

155

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10 August 2017

5

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10 August 2017

1399-1402

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Genetic instability and the mutator phenotype. Studies in ulcerative colitis

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Cancer epigenetics comes of age

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Causes and consequences of microsatellite instability in endometrial carcinoma.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Alterations in DNA methylation: a fundamental aspect of neoplasia

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

DNA methylation and genetic instability in colorectal cancer cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Mutational analysis of mismatch repair genes, hMLH1 and hMSH2, in sporadic endometrial carcinomas with microsatellite instability

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Microsatellite instability in cancer of the proximal colon

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Clues to the pathogenesis of familial colorectal cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Mutation of a mutL homolog in hereditary colon cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Mutations of two PMS homologues in hereditary nonpolyposis colon cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

hMSH2 mutations in hereditary nonpolyposis colorectal cancer kindreds

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Mutations in DNA mismatch repair genes are not responsible for microsatellite instability in most sporadic endometrial carcinomas

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

The short arm of chromosome 11 is a "hot spot" for hypermethylation in human neoplasia

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Allelotype of colorectal carcinomas

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Microsatellite instability in sporadic endometrial carcinoma

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866995

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

25 September 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965451-X

Hypomethylation of DNA from benign and malignant human colon neoplasms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965451-X

Mutational analysis of MLH1 and MSH2 in 25 prospectively-acquired RER+ endometrial cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965451-X

Microsatellite instability and mutation analysis of hMSH2 and hMLH1 in patients with sporadic, familial and hereditary colorectal cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965451-X

MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965451-X

Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas

7 January 2021

1 reference

12 December 2020

Association between CpG island methylation and microsatellite instability in colorectal cancer

1 reference

12 December 2020

E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas

1 reference

12 December 2020

Genetic instability of microsatellites in endometrial carcinoma

1 reference

12 December 2020

Microsatellite instability in endometrial carcinoma

1 reference

12 December 2020

Absence of mutations in DNA mismatch repair genes in sporadic endometrial tumors with microsatellite instability

1 reference

12 December 2020

10.1016/S0002-9440(10)65451-X

Identifiers

DOI

1 reference

10 August 2017

1 reference

10 August 2017

1 reference

PubMed ID

10550292