Structural perturbations in the Ala --> Val polymorphism of methylenetetrahydrofolate reductase: how binding of folates may protect against inactivation (Q35792429)

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scientific article published on April 2006

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English	Structural perturbations in the Ala --> Val polymorphism of methylenetetrahydrofolate reductase: how binding of folates may protect against inactivation	scientific article published on April 2006

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scholarly article

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19 January 2020

Structural perturbations in the Ala --> Val polymorphism of methylenetetrahydrofolate reductase: how binding of folates may protect against inactivation (English)

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19 January 2020

Elizabeth A Campbell

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19 January 2020

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Robert Pejchal

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19 January 2020

Brian D Guenther

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19 January 2020

Brett W Lennon

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19 January 2020

Rowena G Matthews

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19 January 2020

Martha L Ludwig

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19 January 2020

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1 April 2006

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19 January 2020

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19 January 2020

45

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19 January 2020

15

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19 January 2020

4808-4818

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19 January 2020

Dose-dependent effects of folic acid on blood concentrations of homocysteine: a meta-analysis of the randomized trials

1 reference

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Structures of NADH and CH3-H4folate complexes of Escherichia coli methylenetetrahydrofolate reductase reveal a spartan strategy for a ping-pong reaction

1 reference

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Heterogeneity and inaccuracy in protein structures solved by X-ray crystallography.

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Effects of common polymorphisms on the properties of recombinant human methylenetetrahydrofolate reductase

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The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia

1 reference

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12 July 2018

The "thermolabile" variant of methylenetetrahydrofolate reductase and neural tube defects: An evaluation of genetic risk and the relative importance of the genotypes of the embryo and the mother.

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Purification and properties of NADH-dependent 5, 10-methylenetetrahydrofolate reductase (MetF) from Escherichia coli.

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Methylenetetrahydrofolate reductase and methionine synthase: biochemistry and molecular biology

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12 July 2018

Homocysteine and cardiovascular disease

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12 July 2018

The effects of folic acid supplementation on plasma total homocysteine are modulated by multivitamin use and methylenetetrahydrofolate reductase genotypes.

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12 July 2018

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12 July 2018

Human methylenetetrahydrofolate reductase: isolation of cDNA, mapping and mutation identification

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12 July 2018

Thermolabile 5,10-methylenetetrahydrofolate reductase as a cause of mild hyperhomocysteinemia

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12 July 2018

Seven novel mutations in the methylenetetrahydrofolate reductase gene and genotype/phenotype correlations in severe methylenetetrahydrofolate reductase deficiency

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A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

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Methylenetetrahydrofolate reductase. Evidence for spatially distinct subunit domains obtained by scanning transmission electron microscopy and limited proteolysis.

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Homocystinuria associated with decreased methylenetetrahydrofolate reductase activity

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Allosteric inhibition of methylenetetrahydrofolate reductase by adenosylmethionine. Effects of adenosylmethionine and NADPH on the equilibrium between active and inactive forms of the enzyme and on the kinetics of approach to equilibrium

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Thermolabile methylenetetrahydrofolate reductase: an inherited risk factor for coronary artery disease.

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1 reference

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1 reference

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1 reference

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1 reference

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inferred from PubMed ID database lookup

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1 reference

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1 reference

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Identifiers

10.1021/BI052294C

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19 January 2020

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19 January 2020

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19 January 2020

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