PEGylation of a factor VIII-phosphatidylinositol complex: pharmacokinetics and immunogenicity in hemophilia A mice (Q35793113)

10 August 2017

title

PEGylation of a factor VIII-phosphatidylinositol complex: pharmacokinetics and immunogenicity in hemophilia A mice (English)

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10 August 2017

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Coagulation factor VIII

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Aaron Peng

1

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10 August 2017

Matthew P Kosloski

2

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10 August 2017

Genki Nakamura

3

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10 August 2017

Hong Ding

4

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10 August 2017

Sathy V Balu-Iyer

5

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10 August 2017

language of work or name

English

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publication date

16 December 2011

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10 August 2017

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10 August 2017

volume

14

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10 August 2017

issue

1

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10 August 2017

page(s)

35-42

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Downregulation of CD40 signal and induction of TGF-β by phosphatidylinositol mediates reduction in immunogenicity against recombinant human Factor VIII

10 August 2017

cites work

1 reference

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Phosphatidylinositol containing lipidic particles reduces immunogenicity and catabolism of factor VIII in hemophilia a mice

27 July 2018

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T cell-independent B cell response is responsible for ABC phenomenon induced by repeated injection of PEGylated liposomes

27 July 2018

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Rational design of a fully active, long-acting PEGylated factor VIII for hemophilia A treatment

27 July 2018

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Delivery of therapeutic proteins

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Prophylactic therapy in haemophilia

27 July 2018

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Effect of route of administration of human recombinant factor VIII on its immunogenicity in Hemophilia A mice

27 July 2018

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Passive transfer of polyethylene glycol to liposomal-recombinant human FVIII enhances its efficacy in a murine model for hemophilia A.

27 July 2018

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Phosphatidylserine containing liposomes reduce immunogenicity of recombinant human factor VIII (rFVIII) in a murine model of hemophilia A.

27 July 2018

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The B domain of coagulation factor VIII interacts with the asialoglycoprotein receptor

27 July 2018

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Lower inhibitor development in hemophilia A mice following administration of recombinant factor VIII-O-phospho-L-serine complex

27 July 2018

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Intensive exposure to factor VIII is a risk factor for inhibitor development in mild hemophilia A.

27 July 2018

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Pharmacokinetics of factor VIII and factor IX

27 July 2018

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Low density lipoprotein receptor-related protein and factor IXa share structural requirements for binding to the A3 domain of coagulation factor VIII.

27 July 2018

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Hemophilia A--from basic science to clinical practice

27 July 2018

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Catabolism of the coagulation factor VIII: can we prolong lifetime of f VIII in circulation?

27 July 2018

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A systematic review of the associations between dose regimens and medication compliance

27 July 2018

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The hemophilias--from royal genes to gene therapy

27 July 2018

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Structure of the C2 domain of human factor VIII at 1.5 A resolution

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

Analysis of the human factor VIII A2 inhibitor epitope by alanine scanning mutagenesis

27 July 2018

1 reference

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Effect of sterical stabilization on macrophage uptake in vitro and on thickness of the fixed aqueous layer of liposomes made from alkylphosphocholines.

27 July 2018

1 reference

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Inhibitors in congenital haemophilia

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

Pharmacokinetic dosing in prophylactic treatment of hemophilia A.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

The size of human factor VIII heterodimers and the effects produced by thrombin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

Proteolytic processing of human factor VIII. Correlation of specific cleavages by thrombin, factor Xa, and activated protein C with activation and inactivation of factor VIII coagulant activity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

The coagulation cascade: initiation, maintenance, and regulation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

Effect of covalent attachment of polyethylene glycol on immunogenicity and circulating life of bovine liver catalase

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

Factor VIII efficient and specific non-covalent binding to PEGylated liposomes enables prolongation of its circulation time and haemostatic efficacy.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

T cell recognition of the A2 domain of coagulation factor VIII in hemophilia patients and healthy subjects

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

Epitope repertoire of human CD4(+) T cells on the A3 domain of coagulation factor VIII.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

Topology of factor VIII bound to phosphatidylserine-containing model membranes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

Phosphorus assay in column chromatography

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

Human CD4+ T-cell epitope repertoire on the C2 domain of coagulation factor VIII.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

Circulation and biodistribution profiles of long-circulating PEG-liposomes of various sizes in rabbits

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

Liposome clearance in mice: the effect of a separate and combined presence of surface charge and polymer coating

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

3-Dimensional structure of membrane-bound coagulation factor VIII: modeling of the factor VIII heterodimer within a 3-dimensional density map derived by electron crystallography

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

High titre inhibitor after continuous factor VIII administration for surgery in a young infant

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

Residues Glu2181-Val2243 contain a major determinant of the inhibitory epitope in the C2 domain of human factor VIII.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

Some human inhibitor antibodies interfere with factor VIII binding to factor IX.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

A human alloantibody interferes with binding of factor IXa to the factor VIII light chain.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

Applying Bailer's method for AUC confidence intervals to sparse sampling.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

Disulfide bridges of a cysteine-rich repeat of the LDL receptor ligand-binding domain

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

Some factor VIII inhibitor antibodies recognize a common epitope corresponding to C2 domain amino acids 2248 through 2312, which overlap a phospholipid-binding site.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291190

Covalent attachment of immunoglobulins to liposomes via glycosphingolipids

25 September 2018

1 reference

12 December 2020

Factor VIII structure and function

1 reference

12 December 2020

Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes

1 reference

12 December 2020

Factor VIII and factor VIIIa

1 reference

12 December 2020

Residues 484-508 contain a major determinant of the inhibitory epitope in the A2 domain of human factor VIII

1 reference

12 December 2020

The Nijmegen modification of the Bethesda assay for factor VIII:C inhibitors: improved specificity and reliability

1 reference

12 December 2020

The Light Chain of Factor VIII Comprises a Binding Site for Low Density Lipoprotein Receptor-related Protein

1 reference

12 December 2020

Human inhibitor antibodies specific for the factor VIII A2 domain disrupt the interaction between the subunit and factor IXa

1 reference

12 December 2020

Spleen plays an important role in the induction of accelerated blood clearance of PEGylated liposomes

1 reference

12 December 2020

Accelerated blood clearance of PEGylated liposomes upon repeated injections: effect of doxorubicin-encapsulation and high-dose first injection

1 reference

12 December 2020

Phospholipid binding improves plasma survival of factor VIII

1 reference

12 December 2020

Role of the low density lipoprotein-related protein receptor in mediation of factor VIII catabolism

1 reference

12 December 2020

Characterization of antibodies induced by human factor VIII in a murine knockout model of hemophilia A

1 reference

12 December 2020

Cell surface heparan sulfate proteoglycans participate in factor VIII catabolism mediated by low density lipoprotein receptor-related protein

1 reference

12 December 2020

10.1208/S12248-011-9309-2

Identifiers

DOI

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Dimensions Publication ID

10 August 2017

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10 August 2017

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