Differences in human meibum lipid composition with meibomian gland dysfunction using NMR and principal component analysis (Q35797253)

10 August 2017

Differences in human meibum lipid composition with meibomian gland dysfunction using NMR and principal component analysis (English)

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principal component analysis

10 August 2017

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Meibomian gland dysfunction

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Douglas Borchman

1

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10 August 2017

Gary N Foulks

series ordinal

2

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10 August 2017

Marta C Yappert

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3

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10 August 2017

Sarah E Milliner

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4

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10 August 2017

language of work or name

English

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publication date

25 January 2012

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Investigative Ophthalmology Visual Science

10 August 2017

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10 August 2017

53

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10 August 2017

1

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10 August 2017

337-347

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Changes in human meibum lipid composition with age using nuclear magnetic resonance spectroscopy

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Analysis of the composition of lipid in human meibum from normal infants, children, adolescents, adults, and adults with meibomian gland dysfunction using ¹H-NMR spectroscopy

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

The international workshop on meibomian gland dysfunction: report of the subcommittee on tear film lipids and lipid-protein interactions in health and disease.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Human meibum lipid conformation and thermodynamic changes with meibomian-gland dysfunction

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Nonobvious obstructive meibomian gland dysfunction

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Chemistry and biotechnology of carotenoids

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Meibomian gland dysfunction: the past, present, and future

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Lycopene in atherosclerosis prevention: an integrated scheme of the potential mechanisms of action from cell culture studies

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Changes in human meibum lipid with meibomian gland dysfunction using principal component analysis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Topical azithromycin therapy for meibomian gland dysfunction: clinical response and lipid alterations

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Lipids and the ocular lens

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Physical changes in human meibum with age as measured by infrared spectroscopy

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Reevaluation of the phospholipid composition in membranes of adult human lenses by (31)P NMR and MALDI MS.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Human tear film and meibum. Very long chain wax esters and (O-acyl)-omega-hydroxy fatty acids of meibum

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Branched-chain fatty acids, increased in tears of blepharitis patients, are not toxic for conjunctival cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Cholesteryl esters as a depot for very long chain fatty acids in human meibum

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Tetrahdroxysqualene from Rhus taitensis shows antimycobacterial activity against Mycobacterium tuberculosis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Understanding and analyzing meibomian lipids--a review

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

On the lipid composition of human meibum and tears: comparative analysis of nonpolar lipids

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Lipids of human meibum: mass-spectrometric analysis and structural elucidation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Liquid chromatography-mass spectrometric analysis of lipids present in human meibomian gland secretions

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Temperature-induced conformational changes in human tearlipids hydrocarbon chains

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

The correlation between the tear film lipid layer and dry eye disease

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Spectroscopic evaluation of human tear lipids

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Efficacy of a new warm moist air device on tear functions of patients with simple meibomian gland dysfunction

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Meibomian gland dysfunction: a clinical scheme for description, diagnosis, classification, and grading.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Non-invasive methods of assessing the tear film

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

A thorough study of the surface wax of apple fruits

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Therapy for meibomian gland disease

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

The evolving treatment of dry eye.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Conformational studies of sphingolipids by NMR spectroscopy. I. Dihydrosphingomyelin

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

The meibomian glands and tear film lipids. Structure, function, and control

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Tear film lipid layer formation: implications for contact lens wear.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Beta-carotene, carotenoids, and disease prevention in humans.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

In vitro biological methods for determination of carotenoid activity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

NMR chemical shift reagents in structural determination of lipid derivatives: III. Methyl ricinoleate and methyl 12-hydroxystearate

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Lycopene as the most efficient biological carotenoid singlet oxygen quencher

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Effects of polar carotenoids on dimyristoylphosphatidylcholine membranes: a spin-label study

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Molecular evolution of biomembranes: structural equivalents and phylogenetic precursors of sterols

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Meibomian Keratoconjunctivitis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Quantification of human sebum on skin and human meibum on the eye lid margin using Sebutape®, spectroscopy and chemical analysis.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Influence of harvest method and period on olive oil composition: an NMR and statistical study

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Confirmation of changes in human meibum lipid infrared spectra with age using principal component analysis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Quantitative evaluation of sebum lipid components with nuclear magnetic resonance

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Tear film dynamics in floppy eyelid syndrome

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

C31-C34 methylated squalenes from a Bolivian strain of Botryococcus braunii

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Concentriols B, C and D, three squalene-type triterpenoids from the ascomycete Daldinia concentrica

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Lipid-protein stoichiometries in a crystalline biological membrane: NMR quantitative analysis of the lipid extract of the purple membrane

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

Spectroscopic detection of lipid peroxidation products and structural changes in a sphingomyelin model system.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292369

The role of cholesterol in chronic blepharitis

25 September 2018

1 reference

12 December 2020

Meibomianitis: polar lipid abnormalities

1 reference

12 December 2020

Ocular surface changes and discomfort in patients with meibomian gland dysfunction

1 reference

12 December 2020

Separation and characterization of the unknown phospholipid in human lens membranes

1 reference

12 December 2020

An NMR and molecular mechanics study of squalene and squalene derivatives

1 reference

12 December 2020

Characterization of human meibum lipid using raman spectroscopy

1 reference

12 December 2020

Ocular evaporation in meibomian gland dysfunction and dry eye

1 reference

12 December 2020

Detection of Aldehydes and Their Conjugated Hydroperox Ydiene Precursors in Thermally-Stressed Culinary Oils and Fats: Investigations Using High Resolution Proton Nmr Spectroscopy

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12 December 2020

Competitive carotenoid and cholesterol incorporation into liposomes: effects on membrane phase transition, fluidity, polarity and anisotropy

1 reference

12 December 2020

Characteristics of the pre-lens tear film during hydrogel contact lens wear

1 reference

12 December 2020

Correlation of tear lipid layer interference patterns with the diagnosis and severity of dry eye

1 reference

12 December 2020

Tear lipid layer structure and stability following expression of the meibomian glands

1 reference

12 December 2020

Meibomian gland diagnostic expressibility: correlation with dry eye symptoms and gland location

1 reference

12 December 2020

1H and 13C NMR studies of melon and head blubber of the striped dolphin (Stenella coeruleoalba)

1 reference

12 December 2020

Effect of beta-carotene on structural and dynamic properties of model phosphatidylcholine membranes. I. An EPR spin label study

1 reference

12 December 2020

Human crystalline lens phospholipid analysis with age

1 reference

12 December 2020

Spectral characterization of lipid peroxidation in rabbit lens membranes induced by hydrogen peroxide in the presence of Fe2+/Fe3+ cations: a site-specific catalyzed oxidation

1 reference

12 December 2020

Regional and age-dependent differences in the phospholipid composition of human lens membranes

1 reference

12 December 2020

Carotenoid-membrane interactions in liposomes: effect of dipolar, monopolar, and nonpolar carotenoids

1 reference

12 December 2020

Meibomian gland triglyceride fatty acid differences in chronic blepharitis patients

1 reference

12 December 2020

The oils of the meibomian glands. Physical and surface characteristics

1 reference

12 December 2020

Association of meibum oleic acid with meibomian seborrhea

1 reference

12 December 2020

Human lens phospholipid changes with age and cataract

1 reference

12 December 2020

Carotenoid incorporation into microsomes: yields, stability and membrane dynamics

1 reference

12 December 2020

Keratoconjunctivitis sicca associated with meibomian secretion polar lipid abnormality

1 reference

12 December 2020

Identifiers

DOI

10.1167/IOVS.11-8551

1 reference

10 August 2017

1 reference

10 August 2017

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