Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin. (Q35800066)

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9 November 2019

title

Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin (English)

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9 November 2019

2

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author name string

S Kimura

series ordinal

1

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9 November 2019

D Metcalf

series ordinal

3

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W S Alexander

series ordinal

4

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9 November 2019

language of work or name

English

0 references

publication date

1 February 1998

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Proceedings of the National Academy of Sciences of the United States of America

9 November 2019

published in

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volume

95

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issue

3

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9 November 2019

page(s)

1195-1200

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describes a project that uses

9 November 2019

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC18717/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Murine hematopoietic stem cells committed to macrophage/dendritic cell formation: stimulation by Flk2-ligand with enhancement by regulators using the gp130 receptor chain

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Prevention of thrombocytopenia and neutropenia in a nonhuman primate model of marrow suppressive chemotherapy by combining pegylated recombinant human megakaryocyte growth and development factor and recombinant human granulocyte colony-stimulating f

11 July 2018

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Thrombopoietic effects of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) in patients with advanced cancer

11 July 2018

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Thrombopoietin stimulates megakaryocytopoiesis, myelopoiesis, and expansion of CD34+ progenitor cells from single CD34+Thy-1+Lin- primitive progenitor cells

11 July 2018

1 reference

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Thrombopoietin accelerates platelet, red blood cell, and neutrophil recovery in myelosuppressed mice.

11 July 2018

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Thrombopoietin, the ligand for the Mpl receptor, synergizes with steel factor and other early acting cytokines in supporting proliferation of primitive hematopoietic progenitors of mice

11 July 2018

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Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietic receptor c-Mpl

11 July 2018

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Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin

11 July 2018

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Differentiation and proliferation of hematopoietic stem cells

11 July 2018

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Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin

11 July 2018

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Thrombocytopenia in c-mpl-deficient mice

11 July 2018

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Interleukin-6 is required in vivo for the regulation of stem cells and committed progenitors of the hematopoietic system.

11 July 2018

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Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors

11 July 2018

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Purification and biologic characterization of plasma-derived megakaryocyte growth and development factor.

11 July 2018

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Y-encoded, species-specific DNA in mice: evidence that the Y chromosome exists in two polymorphic forms in inbred strains

11 July 2018

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Sequence of the murine and human cellular myc oncogenes and two modes of myc transcription resulting from chromosome translocation in B lymphoid tumours.

11 July 2018

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Loss of stem cell repopulating ability upon transplantation. Effects of donor age, cell number, and transplantation procedure

11 July 2018

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Quantitative responsiveness of murine hemopoietic populations in vitro and in vivo to recombinant multi-CSF (IL-3).

11 July 2018

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MPLV: a retrovirus complex inducing an acute myeloproliferative leukemic disorder in adult mice

11 July 2018

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Quantitative assay for totipotent reconstituting hematopoietic stem cells by a competitive repopulation strategy

11 July 2018

1 reference

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Lineage commitment of hemopoietic progenitor cells in developing blast cell colonies: influence of colony-stimulating factors

11 July 2018

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Hereditary anemias of the mouse: a review for geneticists

11 July 2018

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Ability of early acting cytokines to directly promote survival and suppress apoptosis of human primitive CD34+CD38- bone marrow cells with multilineage potential at the single-cell level: key role of thrombopoietin

11 July 2018

1 reference

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Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo

25 September 2018

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Leukaemia inhibitory factor is necessary for maintenance of haematopoietic stem cells and thymocyte stimulation

25 September 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.95.3.1195

Low levels of erythroid and myeloid progenitors in thrombopoietin-and c-mpl-deficient mice

21 January 2018

1 reference

12 December 2020

Thrombopoietin supports proliferation of human primitive hematopoietic cells in synergy with steel factor and/or interleukin-3

1 reference

12 December 2020

Thrombopoietin, but not erythropoietin, directly stimulates multilineage growth of primitive murine bone marrow progenitor cells in synergy with early acting cytokines: distinct interactions with the ligands for c-kit and FLT3

1 reference

12 December 2020

Recombinant human c-Mpl ligand (thrombopoietin) not only acts on megakaryocyte progenitors, but also on erythroid and multipotential progenitors in vitro

1 reference

12 December 2020

Competitive repopulation: a new assay for long-term stem cell functional capacity

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12 December 2020

Functional isolation and characterization of human hematopoietic stem cells

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12 December 2020

The Mpl receptor is expressed in the megakaryocytic lineage from late progenitors to platelets

1 reference

12 December 2020

Thrombopoietin (c-mpl ligand) acts synergistically with erythropoietin, stem cell factor, and interleukin-11 to enhance murine megakaryocyte colony growth and increases megakaryocyte ploidy in vitro

1 reference

12 December 2020

Recombinant human megakaryocyte growth and development factor stimulates thrombocytopoiesis in normal nonhuman primates

1 reference

12 December 2020

Modulation of megakaryocytopoiesis by thrombopoietin: the c-Mpl ligand

1 reference

12 December 2020

The effect of thrombopoietin on the proliferation and differentiation of murine hematopoietic stem cells

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.95.3.1195

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9448308%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

0 references

1 reference

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9 November 2019

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