Myeloproliferative disease induced by TEL-PDGFRB displays dynamic range sensitivity to Stat5 gene dosage. (Q35804404)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17218386%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

title

Myeloproliferative disease induced by TEL-PDGFRB displays dynamic range sensitivity to Stat5 gene dosage (English)

1 reference

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24 December 2019

2

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24 December 2019

Lothar Hennighausen

7

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24 December 2019

Michael H Tomasson

8

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24 December 2019

author name string

Jennifer A Cain

1

1 reference

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24 December 2019

Julie O'Neal

3

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24 December 2019

Friederike Kreisel

4

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24 December 2019

AnnaLynn Colson

5

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24 December 2019

Hui Luo

6

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24 December 2019

language of work or name

English

0 references

publication date

11 January 2007

1 reference

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24 December 2019

1 reference

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24 December 2019

volume

109

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24 December 2019

issue

9

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24 December 2019

page(s)

3906-3914

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Src family kinases are important negative regulators of G-CSF-dependent granulopoiesis

24 December 2019

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STAT5 signaling is required for the efficient induction and maintenance of CML in mice

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Clarifying the role of Stat5 in lymphoid development and Abelson-induced transformation

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The JAK2V617F tyrosine kinase mutation in myeloproliferative disorders: status report and immediate implications for disease classification and diagnosis

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c-Myc rapidly induces acute myeloid leukemia in mice without evidence of lymphoma-associated antiapoptotic mutations.

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Native interface of the SAM domain polymer of TEL.

27 July 2018

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The TEL/PDGFbetaR fusion in chronic myelomonocytic leukemia signals through STAT5-dependent and STAT5-independent pathways.

27 July 2018

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Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling

27 July 2018

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TEL/PDGFbetaR fusion protein activates STAT1 and STAT5: a common mechanism for transformation by tyrosine kinase fusion proteins

27 July 2018

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Fatal myeloproliferation, induced in mice by TEL/PDGFbetaR expression, depends on PDGFbetaR tyrosines 579/581

27 July 2018

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STAT activation by the PDGF receptor requires juxtamembrane phosphorylation sites but not Src tyrosine kinase activation

27 July 2018

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A sequence of the CIS gene promoter interacts preferentially with two associated STAT5A dimers: a distinct biochemical difference between STAT5A and STAT5B.

27 July 2018

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Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

27 July 2018

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Activation of Stat5 by platelet-derived growth factor (PDGF) is dependent on phosphorylation sites in PDGF beta-receptor juxtamembrane and kinase insert domains

27 July 2018

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Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains

27 July 2018

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Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

27 July 2018

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Lipopolysaccharide (LPS)-induced macrophage activation and signal transduction in the absence of Src-family kinases Hck, Fgr, and Lyn

27 July 2018

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A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFR beta oncoprotein

27 July 2018

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The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways

27 July 2018

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Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

27 July 2018

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The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells

27 July 2018

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Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation

27 July 2018

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Identification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinases

27 July 2018

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Stat5a/b are essential for normal lymphoid development and differentiation

27 July 2018

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25 September 2018

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Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation

25 September 2018

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Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia

25 September 2018

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Fetal liver myelopoiesis occurs through distinct, prospectively isolatable progenitor subsets

25 September 2018

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Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation

25 September 2018

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25 September 2018

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Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue

25 September 2018

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Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK2

25 September 2018

1 reference

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A Single Amino Acid in the DNA Binding Regions of STAT5A and STAT5B Confers Distinct DNA Binding Specificities

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17218386

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Myc is essential for transformation by TEL/platelet-derived growth factor receptor beta (PDGFRbeta)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17218386

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2006-07-036335

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17218386%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17218386%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference