Product Formation by the Promiscuous Lanthipeptide Synthetase ProcM is under Kinetic Control (Q35806114)

10 August 2017

Product Formation by the Promiscuous Lanthipeptide Synthetase ProcM is under Kinetic Control (English)

1 reference

10 August 2017

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25803126%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Yi Yu

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25803126%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Subha Mukherjee

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25803126%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

language of work or name

English

0 references

publication date

7 April 2015

1 reference

Journal of the American Chemical Society

10 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25803126%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

137

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25803126%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

issue

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25803126%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

5140-5148

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25803126%20AND%20SRC:MED&resulttype=core&format=json

Michael-type cyclizations in lantibiotic biosynthesis are reversible.

7 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

A price to pay for relaxed substrate specificity: a comparative kinetic analysis of the class II lanthipeptide synthetases ProcM and HalM2.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

High divergence of the precursor peptides in combinatorial lanthipeptide biosynthesis.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

Mechanistic studies on the substrate-tolerant lanthipeptide synthetase ProcM

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

Insights into the evolution of lanthipeptide biosynthesis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

Evolution of lanthipeptide synthetases

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

Structural characterization of four prochlorosins: a novel class of lantipeptides produced by planktonic marine cyanobacteria

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

Discovery, biosynthesis, and engineering of lantipeptides

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

Catalytic promiscuity in the biosynthesis of cyclic peptide secondary metabolites in planktonic marine cyanobacteria

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

Distributive and directional behavior of lantibiotic synthetases revealed by high-resolution tandem mass spectrometry.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

Directionality and coordination of dehydration and ring formation during biosynthesis of the lantibiotic nisin

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

Lantibiotics: mode of action, biosynthesis and bioengineering

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

Biosynthesis, immunity, regulation, mode of action and engineering of the model lantibiotic nisin

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

Mutants of the zinc ligands of lacticin 481 synthetase retain dehydration activity but have impaired cyclization activity.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

Post-translational modifications during lantibiotic biosynthesis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

Zinc-catalyzed sulfur alkyation:insights from protein farnesyltransferase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

The use of 4-(2-pyridylazo)resorcinol in studies of zinc release from Escherichia coli aspartate transcarbamoylase.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

Dissecting reactions of nonlinear precursor peptide processing of the class III lanthipeptide curvopeptin.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

NisC binds the FxLx motif of the nisin leader peptide.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

Identification of essential catalytic residues of the cyclase NisC involved in the biosynthesis of nisin.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

Zinc-promoted alkyl transfer: a new role for zinc.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

SpaC and NisC, the cyclases involved in subtilin and nisin biosynthesis, are zinc proteins

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

Modulation of the zinc(II) center in protein farnesyltransferase by mutagenesis of the zinc(II) ligands

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

Alkyl Transfer to Metal Thiolates: Kinetics, Active Species Identification, and Relevance to the DNA Methyl Phosphotriester Repair Center of Escherichia coli Ada.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487812

Intramolecular N-H...S hydrogen bonding in the zinc thiolate complex [Tm(Ph)]ZnSCH2C(O)NHPh: a mechanistic investigation of thiolate alkylation as probed by kinetics studies and by kinetic isotope effects

25 September 2018

1 reference

12 December 2020

The alkylation mechanism of zinc-bound thiolates depends upon the zinc ligands

1 reference

12 December 2020

Determining sites of interaction between prenisin and its modification enzymes NisB and NisC

1 reference

12 December 2020

Thiolate alkylation in tripod zinc complexes: a comparative kinetic study

1 reference

12 December 2020

Identifiers

DOI

10.1021/JACS.5B01409

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25803126%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25803126%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PubMed publication ID

25803126

1 reference