ATIC-ALK: A novel variant ALK gene fusion in anaplastic large cell lymphoma resulting from the recurrent cryptic chromosomal inversion, inv(2)(p23q35). (Q35809839)

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scientific article published on March 2000

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English	ATIC-ALK: A novel variant ALK gene fusion in anaplastic large cell lymphoma resulting from the recurrent cryptic chromosomal inversion, inv(2)(p23q35).	scientific article published on March 2000

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4 November 2019

ATIC-ALK: A novel variant ALK gene fusion in anaplastic large cell lymphoma resulting from the recurrent cryptic chromosomal inversion, inv(2)(p23q35) (English)

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4 November 2019

Gisele W B Colleoni

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4 November 2019

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J A Bridge

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4 November 2019

B Garicochea

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4 November 2019

J Liu

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D A Filippa

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4 November 2019

M Ladanyi

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1 March 2000

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4 November 2019

The American Journal of Pathology

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4 November 2019

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4 November 2019

781-789

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4 November 2019

Inv(2)(p23q35) in anaplastic large-cell lymphoma induces constitutive anaplastic lymphoma kinase (ALK) tyrosine kinase activation by fusion to ATIC, an enzyme involved in purine nucleotide biosynthesis

1 reference

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11 July 2018

Prognostic significance of anaplastic lymphoma kinase (ALK) protein expression in adults with anaplastic large cell lymphoma.

1 reference

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11 July 2018

ALK+ lymphoma: clinico-pathological findings and outcome.

1 reference

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11 July 2018

ALK expression defines a distinct group of T/null lymphomas ("ALK lymphomas") with a wide morphological spectrum.

1 reference

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Translocations, cancer and the puzzle of specificity

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Structure and functional relationships in human pur H

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11 July 2018

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7 January 2021

The NPM/ALK gene fusion in the pathogenesis of anaplastic large cell lymphoma

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11 July 2018

ALK-positive lymphoma: a single disease with a broad spectrum of morphology

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Characterization of molecularly cloned human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase

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11 July 2018

The monoclonal antibody ALK1 identifies a distinct morphological subtype of anaplastic large cell lymphoma associated with 2p23/ALK rearrangements

1 reference

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11 July 2018

ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)

1 reference

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11 July 2018

Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis

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11 July 2018

Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system

1 reference

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11 July 2018

In vivo amplification of the PAX3-FKHR and PAX7-FKHR fusion genes in alveolar rhabdomyosarcoma

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11 July 2018

The t(3;5)(q25.1;q34) of myelodysplastic syndrome and acute myeloid leukemia produces a novel fusion gene, NPM-MLF1.

1 reference

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The human purH gene product, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. Cloning, sequencing, expression, purification, kinetic analysis, and domain mapping

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The t(5;17) variant of acute promyelocytic leukemia expresses a nucleophosmin-retinoic acid receptor fusion

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CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF

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11 July 2018

Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma

1 reference

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11 July 2018

ALK gene products in anaplastic large cell lymphomas and Hodgkin's disease

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11 July 2018

Rearrangements of TRK proto-oncogene in papillary thyroid carcinomas.

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11 July 2018

CD30-positive large cell lymphomas ('Ki-1 lymphoma') are associated with a chromosomal translocation involving 5q35.

1 reference

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11 July 2018

Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease

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11 July 2018

Biochemical detection of novel anaplastic lymphoma kinase proteins in tissue sections of anaplastic large cell lymphoma.

1 reference

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25 September 2018

Nucleolar localization of the nucleophosmin-anaplastic lymphoma kinase is not required for malignant transformation.

1 reference

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25 September 2018

Ki-1-positive anaplastic large-cell lymphoma: a clinicopathologic entity?

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Ki-1/CD30+ (anaplastic) large-cell lymphoma: maturation of a clinicopathologic entity with prospects of effective therapy

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Immunohistochemical, molecular, and cytogenetic analysis of a consecutive series of 20 peripheral T-cell lymphomas and lymphomas of uncertain lineage, including 12 Ki-1 positive lymphomas

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7 January 2021

A novel variant translocation t(2;13) (p23;q34) in Ki-1 large cell anaplastic lymphoma

1 reference

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7 January 2021

Detection of the NPM-ALK genomic rearrangement of Ki-1 lymphoma and isolation of the involved NPM and ALK introns

1 reference

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7 January 2021

Molecular variant of the NPM-ALK rearrangement of Ki-1 lymphoma involving a cryptic ALK splice site

1 reference

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7 January 2021

Novel genomic imbalances in embryonal rhabdomyosarcoma revealed by comparative genomic hybridization and fluorescence in situ hybridization: an intergroup rhabdomyosarcoma study

1 reference

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7 January 2021

Novel formation and amplification of the PAX7-FKHR fusion gene in a case of alveolar rhabdomyosarcoma

1 reference

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7 January 2021

Translocation (1;5)(q32;q35) in CD30+ anaplastic large cell non-Hodgkin lymphona of childhood. A case report

1 reference

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7 January 2021

Diagnosis of t(2;5)(p23;q35)-associated Ki-1 lymphoma with immunohistochemistry

1 reference

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12 December 2020

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Molecular detection of the (2;5) translocation of non-Hodgkin's lymphoma by reverse transcriptase-polymerase chain reaction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10702393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anaplastic large cell lymphomas expressing the novel chimeric protein p80NPM/ALK: a distinct clinicopathologic entity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10702393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High incidence of the t(2;5)(p23;q35) translocation in anaplastic large cell lymphoma and its lack of detection in Hodgkin's disease. Comparison of cytogenetic analysis, reverse transcriptase-polymerase chain reaction, and P-80 immunostaining

1 reference

https://pubmed.ncbi.nlm.nih.gov/10702393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Occurrence of the t(2;5)(p23;q35) in non-Hodgkin's lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10702393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD30 (Ki-1)-positive malignant lymphomas: clinical, immunophenotypic, histologic, and genetic characteristics and differences with Hodgkin's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10702393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of anaplastic lymphoma kinase (ALK) and nucleolar protein nucleophosmin (NPM)-ALK proteins in normal and neoplastic cells with the monoclonal antibody ALK1

1 reference

https://pubmed.ncbi.nlm.nih.gov/10702393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of an anti-ALK antibody in the characterization of anaplastic large-cell lymphoma of childhood

1 reference

https://pubmed.ncbi.nlm.nih.gov/10702393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cryptic inv(2)(p23q35) defines a new molecular genetic subtype of ALK-positive anaplastic large-cell lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10702393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new fusion gene TPM3-ALK in anaplastic large cell lymphoma created by a (1;2)(q25;p23) translocation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10702393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recurrent involvement of 2p23 in inflammatory myofibroblastic tumors

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

t(1;2)(q21;p23) and t(2;3)(p23;q21): two novel variant translocations of the t(2;5)(p23;q35) in anaplastic large cell lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10702393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ki-1 antigen expression defines a favorable clinical subset of non-B cell non-Hodgkin's lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10702393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinicopathologic features and treatment outcome of children with large-cell lymphoma and the t(2;5)(p23;q35)

1 reference

https://pubmed.ncbi.nlm.nih.gov/10702393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1016/S0002-9440(10)64945-0

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4 November 2019

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4 November 2019

1 reference

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4 November 2019

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