Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donors (Q35811149)

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scientific article published on April 1988

Language	Label	Description	Also known as
English	Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donors	scientific article published on April 1988

Statements

scholarly article

1 reference

Europe PubMed Central

10 August 2017

Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donors (English)

1 reference

Europe PubMed Central

10 August 2017

author name string

Nagel JE

1

1 reference

Europe PubMed Central

10 August 2017

Chopra RK

2

1 reference

Europe PubMed Central

10 August 2017

Chrest FJ

3

1 reference

Europe PubMed Central

10 August 2017

McCoy MT

4

1 reference

Europe PubMed Central

10 August 2017

Schneider EL

5

1 reference

Europe PubMed Central

10 August 2017

Holbrook NJ

6

1 reference

Europe PubMed Central

10 August 2017

Adler WH

7

1 reference

Europe PubMed Central

10 August 2017

language of work or name

0 references

publication date

1 April 1988

1 reference

Europe PubMed Central

10 August 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

10 August 2017

81

1 reference

Europe PubMed Central

10 August 2017

4

1 reference

Europe PubMed Central

10 August 2017

1096-1102

1 reference

Europe PubMed Central

10 August 2017

Immunological studies of aging. Decreased production of and response to T cell growth factor by lymphocytes from aged humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329636

11 July 2018

Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed

1 reference

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11 July 2018

T-cell growth factor: complete nucleotide sequence and organization of the gene in normal and malignant cells

1 reference

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11 July 2018

1 reference

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The interleukin-2 T-cell system: a new cell growth model.

1 reference

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A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1 reference

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11 July 2018

Age-dependence of molecular and functional changes in biological membrane properties

1 reference

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Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway

1 reference

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Immunological studies of aging. IX. Impaired proliferation of T lymphocytes detected in elderly humans by flow cytometry

1 reference

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Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose

1 reference

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11 July 2018

Molecular cloning and expression of cDNAs for the human interleukin-2 receptor

1 reference

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Soluble interleukin 2 receptors are released from activated human lymphoid cells in vitro.

1 reference

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The p75 peptide is the receptor for interleukin 2 expressed on large granular lymphocytes and is responsible for the interleukin 2 activation of these cells

1 reference

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11 July 2018

Evidence for negative regulation of T cell growth by low affinity interleukin 2 receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329636

11 July 2018

Demonstration of a non-Tac peptide that binds interleukin 2: a potential participant in a multichain interleukin 2 receptor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329636

11 July 2018

Interleukin 2 high-affinity receptor expression requires two distinct binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329636

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Novel interleukin-2 receptor subunit detected by cross-linking under high-affinity conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329636

11 July 2018

Direct activation of human resting T cells by IL 2: the role of an IL 2 receptor distinct from the Tac protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329636

11 July 2018

Interleukin 2 binding molecule distinct from the Tac protein: analysis of its role in formation of high-affinity receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329636

11 July 2018

Internalization of interleukin 2 is mediated by the beta chain of the high-affinity interleukin 2 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329636

11 July 2018

The released interleukin 2 receptor binds interleukin 2 efficiently

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329636

11 July 2018

Sequential expression of genes involved in human T lymphocyte growth and differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329636

11 July 2018

Interleukin 2 regulates its own receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329636

11 July 2018

The human interleukin-2 receptor: a molecular and biochemical analysis of structure and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329636

11 July 2018

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329636

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T cell growth factor: parameters of production and a quantitative microassay for activity

1 reference

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Transient expression of interleukin 2 receptors. Consequences for T cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329636

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Enumeration of T lymphocyte subsets by monoclonal antibodies in young and aged humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127423

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based on heuristic

inferred from PubMed ID database lookup

T lymphocytes of young and aged rats. II. Functional defects and the role of interleukin-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-mediated immunity in aged mice: an underlying lesion in IL 2 synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127423

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Mitogenic activity of 12-O-tetradecanoyl phorbol-13-acetate on peripheral blood lymphocytes from young and aged adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127423

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Monoclonal antibody analysis of T-lymphocyte subsets in young and aged adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127423

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Induction of DNA synthesis in isolated nuclei by cytoplasmic factors. II. Normal generation of cytoplasmic stimulatory factors by lymphocytes from aged humans with depressed proliferative responses

1 reference

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Dexamethasone-mediated inhibition of human T cell growth factor and gamma-interferon messenger RNA

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Reconstitution of in vivo cell-mediated lympholysis responses in aged mice with interleukin 2

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https://pubmed.ncbi.nlm.nih.gov/3127423

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Lack of correlation between serum cholesterol levels, lymphocyte plasma membrane fluidity and mitogen responsiveness in young and aged chickens

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127423

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Interleukin-2 production and activity in aged humans

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https://pubmed.ncbi.nlm.nih.gov/3127423

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Expression of interleukin 2, interferon-gamma, and the IL 2 receptor by human peripheral blood lymphocytes

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https://pubmed.ncbi.nlm.nih.gov/3127423

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Decline, with age, in the proportion of mouse T cells that express IL-2 receptors after mitogen stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127423

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The role of the accessory cell in mitogen-stimulated human T cell gene expression

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The effect of aging on the expression of interleukin 2 messenger ribonucleic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127423

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Regulation of interleukin-2 receptor expression and receptor release

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127423

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A second human interleukin-2 binding protein that may be a component of high-affinity interleukin-2 receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A soluble interleukin 2 receptor produced by a normal alloreactive human T cell clone binds interleukin 2 with low affinity

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127423

12 December 2020

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inferred from PubMed ID database lookup

The IL-2 receptor beta chain (p70): role in mediating signals for LAK, NK, and proliferative activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/3127423

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Identifiers

10.1172/JCI113422

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

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