Indolinyl-Thiazole Based Inhibitors of Scavenger Receptor-BI (SR-BI)-Mediated Lipid Transport (Q35811972)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26478787%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

title

Indolinyl-Thiazole Based Inhibitors of Scavenger Receptor-BI (SR-BI)-Mediated Lipid Transport (English)

1 reference

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27 February 2020

8

1 reference

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18

Stuart L Schreiber

1 reference

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27 February 2020

14

Sivaraman Dandapani

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27 February 2020

17

Michelle A Palmer

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27 February 2020

1

Chris Dockendorff

1 reference

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27 February 2020

4

Willmen Youngsaye

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27 February 2020

7

Partha P Nag

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27 February 2020

10

Melissa Bennion

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27 February 2020

author name string

Patrick W Faloon

2

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27 February 2020

Miao Yu

3

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27 February 2020

Marsha Penman

5

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27 February 2020

Thomas J F Nieland

6

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27 February 2020

Jun Pu

9

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27 February 2020

Joseph Negri

11

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27 February 2020

Conor Paterson

12

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27 February 2020

Garrett Lam

13

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27 February 2020

José R Perez

15

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27 February 2020

Benito Munoz

16

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27 February 2020

Monty Krieger

19

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27 February 2020

publication date

2 February 2015

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ACS Medicinal Chemistry Letters

27 February 2020

published in

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27 February 2020

volume

6

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27 February 2020

issue

4

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27 February 2020

page(s)

375-380

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Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36

27 February 2020

cites work

1 reference

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Safety and antiviral activity of the HCV entry inhibitor ITX5061 in treatment-naive HCV-infected adults: a randomized, double-blind, phase 1b study

27 July 2018

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Discovery of ITX 4520: a highly potent orally bioavailable hepatitis C virus entry inhibitor

27 July 2018

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Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

27 July 2018

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Structural alert/reactive metabolite concept as applied in medicinal chemistry to mitigate the risk of idiosyncratic drug toxicity: a perspective based on the critical examination of trends in the top 200 drugs marketed in the United States

27 July 2018

1 reference

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Extracellular disulfide bonds support scavenger receptor class B type I-mediated cholesterol transport

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599563

Glycine dimerization motif in the N-terminal transmembrane domain of the high density lipoprotein receptor SR-BI required for normal receptor oligomerization and lipid transport

27 July 2018

1 reference

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Novel HDL-directed pharmacotherapeutic strategies

27 July 2018

1 reference

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Small molecule scavenger receptor BI antagonists are potent HCV entry inhibitors

27 July 2018

1 reference

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Biochemical characterization of cholesteryl ester transfer protein inhibitors

27 July 2018

1 reference

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Role of Scavenger Receptor Class B Type I in Hepatitis C Virus Entry: Kinetics and Molecular Determinants

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599563

Mechanism and regulatory function of CpG signaling via scavenger receptor B1 in primary B cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599563

Scavenger Receptor BI Protects against Septic Death through Its Role in Modulating Inflammatory Response

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599563

High-Avidity Monoclonal Antibodies against the Human Scavenger Class B Type I Receptor Efficiently Block Hepatitis C Virus Infection in the Presence of High-Density Lipoprotein

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599563

A comprehensive listing of bioactivation pathways of organic functional groups

27 July 2018

1 reference

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High density lipoproteins facilitate hepatitis C virus entry through the scavenger receptor class B type I.

27 July 2018

1 reference

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High-density lipoprotein cholesterol as an independent risk factor in cardiovascular disease: assessing the data from Framingham to the Veterans Affairs High--Density Lipoprotein Intervention Trial

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599563

A receptor-mediated pathway for cholesterol homeostasis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599563

Contributions of a disulfide bond and a reduced cysteine side chain to the intrinsic activity of the high-density lipoprotein receptor SR-BI.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599563

Evaluation of ITX 5061, a scavenger receptor B1 antagonist: resistance selection and activity in combination with other hepatitis C virus antivirals

24 September 2018

1 reference

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Scavenger receptor class B, type I: a promising immunotherapy target.

24 September 2018

1 reference

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A novel compound, R-138329, increases plasma HDL cholesterol via inhibition of scavenger receptor BI-mediated selective lipid uptake

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599563

Biological evaluation of 1-alkyl-3-phenylthioureas as orally active HDL-elevating agents

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599563

The role of the high-density lipoprotein receptor SR-BI in the lipid metabolism of endocrine and other tissues

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599563

Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599563

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599563

Identification of scavenger receptor SR-BI as a high density lipoprotein receptor

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599563

Influence of HDL-cholesterol-elevating drugs on the in vitro activity of the HDL receptor SR-BI

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26478787

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/ML500154Q

1 reference

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27 February 2020

1 reference

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27 February 2020

1 reference

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