Phase I study of the synthetic triterpenoid, 2-cyano-3, 12-dioxoolean-1, 9-dien-28-oic acid (CDDO), in advanced solid tumors (Q35813082)

10 August 2017

Phase I study of the synthetic triterpenoid, 2-cyano-3, 12-dioxoolean-1, 9-dien-28-oic acid (CDDO), in advanced solid tumors (English)

1 reference

10 August 2017

Giovanna Speranza

1

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10 August 2017

Martin E Gutierrez

2

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10 August 2017

Shivaani Kummar

3

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10 August 2017

John M Strong

4

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10 August 2017

Robert J Parker

5

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10 August 2017

Jerry Collins

6

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10 August 2017

Yunkai Yu

7

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10 August 2017

Liang Cao

8

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10 August 2017

Anthony J Murgo

9

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10 August 2017

James H Doroshow

10

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10 August 2017

Alice Chen

11

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10 August 2017

31 July 2011

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Cancer Chemotherapy and Pharmacology

10 August 2017

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10 August 2017

69

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10 August 2017

2

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10 August 2017

431-438

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https://scigraph.springernature.com/pub.10.1007/s00280-011-1712-y

10 August 2017

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A qualitative study evaluating causality attribution for serious adverse events during early phase oncology clinical trials

27 July 2018

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Role of peroxisome proliferator-activated receptor-gamma and its coactivator DRIP205 in cellular responses to CDDO (RTA-401) in acute myelogenous leukemia

27 July 2018

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27 July 2018

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Pentacyclic triterpenes of the lupane, oleanane and ursane group as tools in cancer therapy

27 July 2018

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27 July 2018

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Ganoderma lucidum extract attenuates the proliferation of hepatic stellate cells by blocking the PDGF receptor

27 July 2018

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Addiction to elevated insulin-like growth factor I receptor and initial modulation of the AKT pathway define the responsiveness of rhabdomyosarcoma to the targeting antibody

27 July 2018

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Oleanolic acid, a pentacyclic triterpenoid, induces rabbit platelet aggregation through a phospholipase C-calcium dependent signaling pathway

27 July 2018

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The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia

27 July 2018

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Platelet anti-aggregating triterpenoids from the leaves of Acanthopanax senticosus and the fruits of A. sessiliflorus

27 July 2018

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Activation of peroxisome proliferator-activated receptor gamma by a novel synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest and apoptosis in breast cancer cells

27 July 2018

1 reference

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An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis

27 July 2018

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A synthetic triterpenoid, 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO), is a ligand for the peroxisome proliferator-activated receptor gamma

27 July 2018

1 reference

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New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

27 July 2018

1 reference

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CDDO induces apoptosis via the intrinsic pathway in lymphoid cells.

27 July 2018

1 reference

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The novel synthetic oleanane triterpenoid CDDO (2-cyano-3, 12-dioxoolean-1, 9-dien-28-oic acid) induces apoptosis in Mycosis fungoides/Sézary syndrome cells

21 January 2018

1 reference

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Growth-inhibitory effect of a novel synthetic triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, on ovarian carcinoma cell lines not dependent on peroxisome proliferator-activated receptor-gamma expression

21 January 2018

1 reference

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Methyl 2-cyano-3,12-dioxooleana-1,9-dien-28-oate decreases specificity protein transcription factors and inhibits pancreatic tumor growth: role of microRNA-27a

21 January 2018

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High preoperative prevalence of deep venous thrombosis in patients with colorectal cancer

21 January 2018

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Synthetic triterpenoids activate a pathway for apoptosis in AML cells involving downregulation of FLIP and sensitization to TRAIL.

21 January 2018

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The triterpenoid CDDO induces apoptosis in refractory CLL B cells

21 January 2018

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The novel synthetic triterpenoid, CDDO-imidazolide, inhibits inflammatory response and tumor growth in vivo.

21 January 2018

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The novel triterpenoid CDDO induces apoptosis and differentiation of human osteosarcoma cells by a caspase-8 dependent mechanism

24 September 2018

1 reference

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Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4490274

Ovarian cancer and venous thromboembolic risk

24 September 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1712-Y

Clinical outcomes and factors predicting development of venous thromboembolic complications in patients with advanced refractory cancer in a Phase I Clinic: the M. D. Anderson Cancer Center experience

21 January 2018

1 reference

12 December 2020

Triterpenes from Acanthopanax sessiliflorus fruits and their antiplatelet aggregation activities

1 reference

12 December 2020

Anti-platelet aggregation triterpene saponins from the galls of Sapindus mukorossi

1 reference

12 December 2020

Accelerated titration designs for phase I clinical trials in oncology

1 reference

12 December 2020

Venous thrombosis in patients with solid tumors: determination of frequency and characteristics

1 reference

12 December 2020

10.1007/S00280-011-1712-Y

Identifiers

DOI

1 reference

10 August 2017

1 reference

10 August 2017

1 reference