Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor (Q35819584)

10 August 2017

Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor (English)

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10 August 2017

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Joana C d'Avila

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10 August 2017

Tina I Lam

2

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10 August 2017

Deborah Bingham

3

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10 August 2017

Jian Shi

4

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10 August 2017

Seok Joon Won

5

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10 August 2017

Tiina M Kauppinen

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10 August 2017

Stephen Massa

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10 August 2017

Jialing Liu

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10 August 2017

Raymond A Swanson

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10 August 2017

language of work or name

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15 February 2012

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Journal of Neuroinflammation

10 August 2017

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10 August 2017

9

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10 August 2017

31

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describes a project that uses

10 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3298794/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1186/1742-2094-9-31

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Microglial activation in stroke: therapeutic targets

11 July 2018

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Role of microglia in neurotrauma

11 July 2018

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Effect of acute poly(ADP-ribose) polymerase inhibition by 3-AB on blood-brain barrier permeability and edema formation after focal traumatic brain injury in rats.

11 July 2018

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NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death

11 July 2018

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Adenosine A1 receptor activation as a brake on the microglial response after experimental traumatic brain injury in mice

11 July 2018

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Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice

11 July 2018

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11 July 2018

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Drug targets for traumatic brain injury from poly(ADP-ribose)polymerase pathway modulation.

11 July 2018

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The bright side of the glial scar in CNS repair

11 July 2018

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A randomized, placebo-controlled trial to evaluate the tolerability, safety, pharmacokinetics, and pharmacodynamics of a potent inhibitor of poly(ADP-ribose) polymerase (INO-1001) in patients with ST-elevation myocardial infarction undergoing primar

11 July 2018

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Zinc triggers microglial activation

11 July 2018

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Quantification of poly(ADP-ribose)-modified proteins in cerebrospinal fluid from infants and children after traumatic brain injury.

11 July 2018

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Transcriptional control by PARP-1: chromatin modulation, enhancer-binding, coregulation, and insulation

11 July 2018

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The vermicelli handling test: a simple quantitative measure of dexterous forepaw function in rats

11 July 2018

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A rose by any other name? The potential consequences of microglial heterogeneity during CNS health and disease

11 July 2018

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Inflammation in ischemic brain injury: timing is important

11 July 2018

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Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

11 July 2018

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The role of poly(ADP-ribose) polymerase-1 in CNS disease

11 July 2018

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Statin withdrawal: clinical implications and molecular mechanisms

11 July 2018

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Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations.

11 July 2018

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Rebound inflammation and the risk of ischemic stroke after discontinuation of aspirin therapy

11 July 2018

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Poly(ADP-ribosyl)ation regulation of life and death in the nervous system

11 July 2018

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The functional role of poly(ADP-ribose)polymerase 1 as novel coactivator of NF-kappaB in inflammatory disorders

11 July 2018

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Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

11 July 2018

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Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia

11 July 2018

1 reference

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Increased neurogenesis in the dentate gyrus after transient global ischemia in gerbils.

11 July 2018

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NF-kappa B: a crucial transcription factor for glial and neuronal cell function

11 July 2018

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Microglia: a sensor for pathological events in the CNS

11 July 2018

1 reference

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Inhibition of poly(ADP-ribose) polymerase suppresses inflammation and promotes recovery after ischemic injury

11 July 2018

1 reference

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Delayed treatment with minocycline ameliorates neurologic impairment through activated microglia expressing a high-mobility group box1-inhibiting mechanism

24 September 2018

1 reference

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Local administration of the poly(ADP-ribose) polymerase inhibitor INO-1001 prevents NAD+ depletion and improves water maze performance after traumatic brain injury in mice.

24 September 2018

1 reference

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Delayed neuronal death after brain trauma involves p53-dependent inhibition of NF-kappaB transcriptional activity.

24 September 2018

1 reference

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Minocycline reduces microglial activation and improves behavioral deficits in a transgenic model of cerebral microvascular amyloid.

24 September 2018

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Use of a poly(ADP-ribose) polymerase inhibitor to suppress inflammation and neuronal death after cerebral ischemia-reperfusion

24 September 2018

1 reference

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Chronic treatment with minocycline preserves adult new neurons and reduces functional impairment after focal cerebral ischemia

24 September 2018

1 reference

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Traumatic injury to the immature brain results in progressive neuronal loss, hyperactivity and delayed cognitive impairments

24 September 2018

1 reference

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Beneficial effects of PJ34 and INO-1001, two novel water-soluble poly(ADP-ribose) polymerase inhibitors, on the consequences of traumatic brain injury in rat.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298794

Poly(ADP-ribose) polymerase-1 promotes microglial activation, proliferation, and matrix metalloproteinase-9-mediated neuron death

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298794

Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298794

Time course of cellular pathology after controlled cortical impact injury.

24 September 2018

1 reference

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A dual role for poly‐ADP‐ribosylation in spatial memory acquisition after traumatic brain injury in mice involving NAD+ depletion and ribosylation of 14‐3‐3γ

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298794

Poly(ADP-ribose) polymerase-1 activity promotes NF-kappaB-driven transcription and microglial activation: implication for neurodegenerative disorders

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298794

Regulation of microglial expression of integrins by poly(ADP-ribose) polymerase-1.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298794

Pharmacologic inhibition of poly(ADP-ribose) polymerase is neuroprotective following traumatic brain injury in rats.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298794

24 September 2018

GFAP and astrogliosis.

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A semiautomated method for measuring brain infarct volume.

24 September 2018

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Rebound of vascular permeability response and its inhibition by hydroxyurea in granulomatous inflammation following withdrawal of glucocorticoid therapy

24 September 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22335939

12 December 2020

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Cessation of dexamethasone exacerbates airway responses to methacholine in asthmatic mice

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22335939

12 December 2020

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Identifiers

DOI

10.1186/1742-2094-9-31

1 reference

Dimensions Publication ID

10 August 2017

1027611709

0 references

Fatcat ID

release_pdobwof3jvfafhdkfdpdrg6mnm

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/pdobwof3jvfafhdkfdpdrg6mnm

24 November 2022

mapped directly with Wikidata item

1 reference

10 August 2017

1 reference