Genetic modification of T lymphocytes for adoptive immunotherapy (Q35826514)

10 August 2017

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title

Genetic modification of T lymphocytes for adoptive immunotherapy (English)

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10 August 2017

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2

Malcolm K Brenner

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10 August 2017

Claudia Rossig

1

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10 August 2017

publication date

1 July 2004

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10 August 2017

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10 August 2017

volume

10

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10 August 2017

issue

1

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10 August 2017

page(s)

5-18

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Adoptive immunotherapy with tumor-infiltrating lymphocytes and interleukin-2 in patients with metastatic malignant melanoma and renal cell carcinoma: a pilot study

10 August 2017

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Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer

7 January 2021

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7 January 2021

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Retroviral transduction of a T cell receptor specific for an Epstein-Barr virus-encoded peptide

7 January 2021

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Immunotherapy through TCR gene transfer

7 January 2021

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The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways

7 January 2021

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Activation of T cells by a tyrosine kinase activation domain in the cytoplasmic tail of CD3 epsilon.

7 January 2021

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Cellular immunity to HIV activated by CD4 fused to T cell or Fc receptor polypeptides

7 January 2021

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Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors

7 January 2021

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Dual-specific T cells combine proliferation and antitumor activity

7 January 2021

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Ligand-mediated cytolysis of tumor cells: use of heregulin-zeta chimeras to redirect cytotoxic T lymphocytes

7 January 2021

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Antitumor activity of cytotoxic T lymphocytes engineered to target vascular endothelial growth factor receptors

7 January 2021

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Regulation of T-cell antigen receptor (TCR) alpha-chain expression by TCR beta-chain transcripts

7 January 2021

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Grafting primary human T lymphocytes with cancer-specific chimeric single chain and two chain TCR.

7 January 2021

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Targeting autoantigen-specific T cells and suppression of autoimmune encephalomyelitis with receptor-modified T lymphocytes

7 January 2021

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Engineering mouse T lymphocytes specific to type II collagen by transduction with a chimeric receptor consisting of a single chain Fv and TCR zeta

7 January 2021

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Characterization of T cell-expressed chimeric receptors with antibody-type specificity for the CD4 binding site of HIV-1 gp120.

7 January 2021

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Systemic T cell-independent tumor immunity after transplantation of universal receptor-modified bone marrow into SCID mice

7 January 2021

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Coupling CD28 co-stimulation to immunoglobulin T-cell receptor molecules: the dynamics of T-cell proliferation and death

7 January 2021

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Reshaping human antibodies: grafting an antilysozyme activity

7 January 2021

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Anti-melanoma antibodies from melanoma patients immunized with genetically modified autologous tumor cells: selection of specific antibodies from single-chain Fv fusion phage libraries

7 January 2021

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The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses

7 January 2021

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Therapeutic vaccination against chronic viral infection: the importance of cooperation between CD4+ and CD8+ T cells

7 January 2021

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CD4+ T cells engrafted with a recombinant immunoreceptor efficiently lyse target cells in a MHC antigen- and Fas-independent fashion.

7 January 2021

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Anti-Tumor CC49-zeta CD4 T cells possess both cytolytic and helper functions.

7 January 2021

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A phase II randomized study of HIV-specific T-cell gene therapy in subjects with undetectable plasma viremia on combination antiretroviral therapy

7 January 2021

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Signals through T cell receptor-zeta chain alone are insufficient to prime resting T lymphocytes

7 January 2021

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The immunological synapse: a molecular machine controlling T cell activation

7 January 2021

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A Theory of Self-Nonself Discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectively

7 January 2021

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Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction

7 January 2021

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CD28/B7 system of T cell costimulation

7 January 2021

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Costimulation by CD48 and B7-1 induces immunity against poorly immunogenic tumors

7 January 2021

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Antigen-specific targeting of CD28-mediated T cell co-stimulation using chimeric single-chain antibody variable fragment-CD28 receptors

7 January 2021

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Antigen-dependent CD28 signaling selectively enhances survival and proliferation in genetically modified activated human primary T lymphocytes

7 January 2021

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Integrated src kinase and costimulatory activity enhances signal transduction through single-chain chimeric receptors in T lymphocytes.

7 January 2021

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Tumor-specific T cell activation by recombinant immunoreceptors: CD3 zeta signaling and CD28 costimulation are simultaneously required for efficient IL-2 secretion and can be integrated into one combined CD28/CD3 zeta signaling receptor molecule

7 January 2021

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Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRζ /CD28 receptor

7 January 2021

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Single-chain antigen recognition receptors that costimulate potent rejection of established experimental tumors

7 January 2021

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Activation of resting human primary T cells with chimeric receptors: costimulation from CD28, inducible costimulator, CD134, and CD137 in series with signals from the TCR zeta chain

7 January 2021

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Identification of a murine CD28 dileucine motif that suppresses single-chain chimeric T-cell receptor expression and function.

7 January 2021

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Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice

7 January 2021

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Direct T cell activation by chimeric single chain Fv-Syk promotes Syk-Cbl association and Cbl phosphorylation

7 January 2021

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Role of cytotoxic T lymphocytes in Epstein-Barr virus-associated diseases

7 January 2021

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Epstein-Barr virus-specific human T lymphocytes expressing antitumor chimeric T-cell receptors: potential for improved immunotherapy

7 January 2021

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Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

7 January 2021

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Induction of apoptosis in experimental human B cell lymphomas by conditional TRAIL-expressing T cells

7 January 2021

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Combined chemokine and cytokine gene transfer enhances antitumor immunity

7 January 2021

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Autocrine growth and tumorigenicity of interleukin 2-dependent helper T cells transfected with IL-2 gene

7 January 2021

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A strategy for treatment of Epstein-Barr virus-positive Hodgkin's disease by targeting interleukin 12 to the tumor environment using tumor antigen-specific T cells

7 January 2021

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Anchoring cytokines to tumor cells for the preparation of anticancer vaccines without gene transfection in mice

7 January 2021

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7 January 2021

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7 January 2021

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Antigen-specific therapy for autoimmune disease

7 January 2021

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Local delivery of interleukin 4 by retrovirus-transduced T lymphocytes ameliorates experimental autoimmune encephalomyelitis.

7 January 2021

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Adoptive immunotherapy of experimental autoimmune encephalomyelitis via T cell delivery of the IL-12 p40 subunit

7 January 2021

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Antigen-specific T cell-mediated gene therapy in collagen-induced arthritis

7 January 2021

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In vivo migration and function of transferred HIV-1-specific cytotoxic T cells

7 January 2021

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Phenotypic analysis of antigen-specific T lymphocytes

7 January 2021

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Bioluminescence imaging of lymphocyte trafficking in vivo.

7 January 2021

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Serial in vivo imaging of the targeted migration of human HSV-TK-transduced antigen-specific lymphocytes

7 January 2021

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Imaging TCR-dependent NFAT-mediated T-cell activation with positron emission tomography in vivo

7 January 2021

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A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

7 January 2021

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Murine leukemia induced by retroviral gene marking

7 January 2021

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AAV serotype 2 vectors preferentially integrate into active genes in mice

7 January 2021

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HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia

7 January 2021

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Herpes simplex virus thymidine kinase gene transfer for controlled graft-versus-host disease and graft-versus-leukemia: clinical follow-up and improved new vectors

7 January 2021

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Elimination of the truncated message from the herpes simplex virus thymidine kinase suicide gene

7 January 2021

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A novel 'sort-suicide' fusion gene vector for T cell manipulation

7 January 2021

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Genetic modification of human T cells with CD20: a strategy to purify and lyse transduced cells with anti-CD20 antibodies

7 January 2021

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T-cell mediated rejection of gene-modified HIV-specific cytotoxic T lymphocytes in HIV-infected patients

7 January 2021

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Folylpolyglutamyl synthetase gene transfer and glioma antifolate sensitivity in culture and in vivo

7 January 2021

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In vivo human carboxylesterase cDNA gene transfer to activate the prodrug CPT-11 for local treatment of solid tumors

7 January 2021

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A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease

7 January 2021

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Expansion and characterization of T cells transduced with a chimeric receptor against ovarian cancer

7 January 2021

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A T cell-independent antitumor response in mice with bone marrow cells retrovirally transduced with an antibody/Fc-gamma chain chimeric receptor gene recognizing a human ovarian cancer antigen

7 January 2021

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Expression in cytotoxic T lymphocytes of a single-chain anti-carcinoembryonic antigen antibody. Redirected Fas ligand-mediated lysis of colon carcinoma

7 January 2021

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A chimeric receptor that selectively targets membrane-bound carcinoembryonic antigen (mCEA) in the presence of soluble CEA.

7 January 2021

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Recognition of human colon cancer by T cells transduced with a chimeric receptor gene

7 January 2021

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Anti-tumor activity of human T cells expressing the CC49-zeta chimeric immune receptor

7 January 2021

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Chimeric scFv/gamma receptor-mediated T-cell lysis of tumor cells is coregulated by adhesion and accessory molecules

7 January 2021

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Functional balance between T cell chimeric receptor density and tumor associated antigen density: CTL mediated cytolysis and lymphokine production

7 January 2021

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Targeting of T lymphocytes to melanoma cells through chimeric anti-GD3 immunoglobulin T-cell receptors

7 January 2021

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Targeting of G(D2)-positive tumor cells by human T lymphocytes engineered to express chimeric T-cell receptor genes

7 January 2021

1 reference

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Generation of gene-modified T cells reactive against the angiogenic kinase insert domain-containing receptor (KDR) found on tumor vasculature

7 January 2021

1 reference

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Specific targeting of EGP-2+ tumor cells by primary lymphocytes modified with chimeric T cell receptors

7 January 2021

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Comparison of the TCR zeta-chain with the FcR gamma-chain in chimeric TCR constructs for T cell activation and apoptosis

7 January 2021

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T-cell clones can be rendered specific for CD19: toward the selective augmentation of the graft-versus-B-lineage leukemia effect

7 January 2021

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Characterization of a chimeric T-cell receptor with specificity for the Hodgkin's lymphoma-associated CD30 antigen

7 January 2021

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.YMTHE.2004.04.014

1 reference

release_ghihxdhszbactgnkzhwx5nfe5e

10 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ghihxdhszbactgnkzhwx5nfe5e

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference