Microbiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase 1 (SCD1) Promotes Metabolic Syndrome in TLR5-Deficient Mice (Q35829504)

10 August 2017

Microbiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase 1 (SCD1) Promotes Metabolic Syndrome in TLR5-Deficient Mice (English)

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10 August 2017

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2

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6 June 2020

Jingwei Cai

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6 June 2020

Rachel E Walker

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6 June 2020

Kevin J Harvatine

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Andrew Patterson

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Andrew T Gewirtz

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6 June 2020

author name string

Vishal Singh

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6 June 2020

Limin Zhang

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Beng San Yeoh

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Xia Xiao

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6 June 2020

Manish Kumar

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6 June 2020

Mark T Baker

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Kamil Borkowski

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Nagendra Singh

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Gregory C Shearer

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James M Ntambi

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Bina Joe

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Matam Vijay-Kumar

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6 June 2020

publication date

27 October 2015

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10 August 2017

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6 June 2020

volume

22

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6 June 2020

page(s)

983-996

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6 June 2020

issue

6

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Short-Chain Fatty Acids Protect Against High-Fat Diet-Induced Obesity via a PPARγ-Dependent Switch From Lipogenesis to Fat Oxidation

6 June 2020

cites work

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Adiposity, gut microbiota and faecal short chain fatty acids are linked in adult humans

27 July 2018

1 reference

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Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis

27 July 2018

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Microbial modulation of energy availability in the colon regulates intestinal transit

27 July 2018

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Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

27 July 2018

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Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

27 July 2018

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Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase

27 July 2018

1 reference

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Gut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids.

27 July 2018

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The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis

27 July 2018

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The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

27 July 2018

1 reference

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Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice

27 July 2018

1 reference

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Higher level of faecal SCFA in women correlates with metabolic syndrome risk factors

27 July 2018

1 reference

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Stearoyl-CoA desaturase: rogue or innocent bystander?

27 July 2018

1 reference

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Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient mice

27 July 2018

1 reference

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Stearoyl-CoA desaturase: a vital checkpoint in the development and progression of obesity

27 July 2018

1 reference

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Stearoyl-coenzyme A desaturase 1 inhibition and the metabolic syndrome: considerations for future drug discovery

27 July 2018

1 reference

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Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5

27 July 2018

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The gut microbiota modulates host energy and lipid metabolism in mice

27 July 2018

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Loss of Stearoyl-CoA desaturase-1 attenuates adipocyte inflammation: effects of adipocyte-derived oleate

27 July 2018

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Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

27 July 2018

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Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome

27 July 2018

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Stearoyl-CoA desaturase-1 deficiency attenuates obesity and insulin resistance in leptin-resistant obese mice

27 July 2018

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Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

27 July 2018

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Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism

27 July 2018

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Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice

27 July 2018

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Metabolomics reveals that hepatic stearoyl-CoA desaturase 1 downregulation exacerbates inflammation and acute colitis

27 July 2018

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Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis

27 July 2018

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Deletion of TLR5 results in spontaneous colitis in mice

27 July 2018

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TLR4 links innate immunity and fatty acid-induced insulin resistance

27 July 2018

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Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppression

27 July 2018

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Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss

27 July 2018

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The N terminus of microsomal delta 9 stearoyl-CoA desaturase contains the sequence determinant for its rapid degradation

27 July 2018

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The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1

27 July 2018

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Differential expression of hepatic stearoyl-CoA desaturase gene 1 in male and female mice.

27 July 2018

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Regulation of lipid synthesis in cultured animal cells

27 July 2018

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The effect of meat protein and dietary fiber on colonic function and metabolism II. Bacterial metabolites in feces and urine

27 July 2018

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Stearoyl-CoA Desaturase: A Control Enzme in Hepatic Lipogenesis

27 July 2018

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Inhibition of Rat-Liver Acetyl-Coenzyme-A Carboxylase by Palmitoyl-Coenzyme A. Formation of Equimolar Enzyme-Inhibitor Complex

27 July 2018

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The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism

27 July 2018

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A targeted metabolomic protocol for short-chain fatty acids and branched-chain amino acids.

24 September 2018

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The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43.

24 September 2018

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Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

24 September 2018

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Germ-free C57BL/6J mice are resistant to high-fat-diet-induced insulin resistance and have altered cholesterol metabolism.

24 September 2018

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An optimised sample preparation method for NMR-based faecal metabonomic analysis.

24 September 2018

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Lipotoxicity: why do saturated fatty acids cause and monounsaturates protect against it?

24 September 2018

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An obesity-associated gut microbiome with increased capacity for energy harvest

24 September 2018

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Microbial ecology: human gut microbes associated with obesity

24 September 2018

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Oleate prevents palmitate-induced cytotoxic stress in cardiac myocytes

24 September 2018

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Stearoyl-CoA desaturase 1 gene expression is necessary for fructose-mediated induction of lipogenic gene expression by sterol regulatory element-binding protein-1c-dependent and -independent mechanisms

24 September 2018

1 reference

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Molecular analysis of the effect of short-chain fatty acids on intestinal cell proliferation

24 September 2018

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Do colonic short-chain fatty acids contribute to the long-term adaptation of blood lipids in subjects with type 2 diabetes consuming a high-fiber diet?

24 September 2018

1 reference

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A lipogenic diet in mice with a disruption of the stearoyl-CoA desaturase 1 gene reveals a stringent requirement of endogenous monounsaturated fatty acids for triglyceride synthesis

24 September 2018

1 reference

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PREPARATION OF FATTY ACID METHYL ESTERS AND DIMETHYLACETALS FROM LIPIDS WITH BORON FLUORIDE--METHANOL

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26525535

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effect of rectal infusion of short chain fatty acids in human subjects

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26525535

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CMET.2015.09.028

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26525535%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26525535%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference