Amyloid beta and the longest-lived rodent: the naked mole-rat as a model for natural protection from Alzheimer's disease. (Q35831849)

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scientific article published on 22 April 2013

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English	Amyloid beta and the longest-lived rodent: the naked mole-rat as a model for natural protection from Alzheimer's disease.	scientific article published on 22 April 2013

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29 February 2020

Amyloid beta and the longest-lived rodent: the naked mole-rat as a model for natural protection from Alzheimer's disease (English)

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29 February 2020

Alzheimer's disease

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Pawel A. Osmulski

4

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29 February 2020

Rochelle Buffenstein

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Rochelle Buffenstein

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29 February 2020

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Yael H Edrey

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29 February 2020

David X Medina

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29 February 2020

Maria Gaczynska

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29 February 2020

Salvatore Oddo

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29 February 2020

Antonella Caccamo

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29 February 2020

publication date

22 April 2013

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29 February 2020

Neurobiology of Aging

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29 February 2020

34

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29 February 2020

10

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29 February 2020

2352-2360

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29 February 2020

describes a project that uses

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11 June 2022

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based on heuristic

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Postsynaptic dysfunction is associated with spatial and object recognition memory loss in a natural model of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4496028

27 July 2018

Sustained high levels of neuregulin-1 in the longest-lived rodents; a key determinant of rodent longevity

1 reference

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27 July 2018

Genome sequencing reveals insights into physiology and longevity of the naked mole rat

1 reference

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27 July 2018

Vitamin D in the healthy and inflamed central nervous system: access and function

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27 July 2018

HH domain of Alzheimer's disease Abeta provides structural basis for neuronal binding in PC12 and mouse cortical/hippocampal neurons

1 reference

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27 July 2018

Abeta40, either soluble or aggregated, is a remarkably potent antioxidant in cell-free oxidative systems

1 reference

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27 July 2018

Reassessing the amyloid cascade hypothesis of Alzheimer's disease

1 reference

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27 July 2018

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

1 reference

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27 July 2018

Animal models of Alzheimer's disease and frontotemporal dementia

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27 July 2018

Oxidative stress in vascular senescence: lessons from successfully aging species

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27 July 2018

Negligible senescence in the longest living rodent, the naked mole-rat: insights from a successfully aging species

1 reference

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27 July 2018

Histidines 13 and 14 in the Abeta sequence are targets for inhibition of Alzheimer's disease Abeta ion channel and cytotoxicity.

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27 July 2018

Human-like rodent amyloid-beta-peptide determines Alzheimer pathology in aged wild-type Octodon degu

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27 July 2018

Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer's disease

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27 July 2018

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

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27 July 2018

Dominance and queen succession in captive colonies of the eusocial naked mole-rat, Heterocephalus glaber

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27 July 2018

Human and rodent sequence analogs of Alzheimer's amyloid beta A4 share similar properties and can be solubilized in buffers of pH 7.4.

1 reference

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27 July 2018

Cholecalciferol has no effect on calcium and inorganic phosphorus balance in a naturally cholecalciferol-deplete subterranean mammal, the naked mole rat (Heterocephalus glaber).

1 reference

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27 July 2018

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

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27 July 2018

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

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27 July 2018

Amyloid-β: the seeds of darkness

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24 September 2018

Successful aging and sustained good health in the naked mole rat: a long-lived mammalian model for biogerontology and biomedical research

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Endocrine function and neurobiology of the longest-living rodent, the naked mole-rat

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Age-related brain pathology in Octodon degu: blood vessel, white matter and Alzheimer-like pathology

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24 September 2018

1alpha,25-dihydroxyvitamin D3 interacts with curcuminoids to stimulate amyloid-beta clearance by macrophages of Alzheimer's disease patients.

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Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat.

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Blocking Abeta42 accumulation delays the onset and progression of tau pathology via the C terminus of heat shock protein70-interacting protein: a mechanistic link between Abeta and tau pathology.

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Low rates of hydrogen peroxide production by isolated heart mitochondria associate with long maximum lifespan in vertebrate homeotherms

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Intracellular amyloid-beta in Alzheimer's disease

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Increased susceptibility to amyloid toxicity in familial Alzheimer's fibroblasts

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24 September 2018

Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice

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24 September 2018

Methylation of the imidazole side chains of the Alzheimer disease amyloid-beta peptide results in abolition of superoxide dismutase-like structures and inhibition of neurotoxicity

1 reference

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24 September 2018

Rodent Abeta(1-42) exhibits oxidative stress properties similar to those of human Abeta(1-42): Implications for proposed mechanisms of toxicity.

1 reference

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Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer’s disease

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24 September 2018

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1 reference

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1 reference

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Evidence that primer pheromones do not cause social suppression of reproduction in male and female naked mole-rats (Heterocephalus glaber)

1 reference

https://pubmed.ncbi.nlm.nih.gov/23618870

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based on heuristic

inferred from PubMed ID database lookup

High oxidative damage levels in the longest-living rodent, the naked mole-rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/23618870

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.NEUROBIOLAGING.2013.03.032

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29 February 2020

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29 February 2020

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29 February 2020

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