Human non-germinal center B cell interleukin (IL)-12 production is primarily regulated by T cell signals CD40 ligand, interferon gamma, and IL-10: role of B cells in the maintenance of T cell responses. (Q35834633)

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scientific article published in January 1999

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English	Human non-germinal center B cell interleukin (IL)-12 production is primarily regulated by T cell signals CD40 ligand, interferon gamma, and IL-10: role of B cells in the maintenance of T cell responses.	scientific article published in January 1999

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8 December 2019

Human non-germinal center B cell interleukin (IL)-12 production is primarily regulated by T cell signals CD40 ligand, interferon gamma, and IL-10: role of B cells in the maintenance of T cell responses (English)

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8 December 2019

Joachim Schultze

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L M Nadler

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8 December 2019

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S Michalak

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J Lowne

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8 December 2019

A Wong

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8 December 2019

J G Gribben

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8 December 2019

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1 January 1999

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8 December 2019

Journal of Experimental Medicine

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8 December 2019

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8 December 2019

1

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8 December 2019

1-12

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8 December 2019

Visualization of specific B and T lymphocyte interactions in the lymph node

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In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas

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Functional diversity of helper T lymphocytes

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Type 1 and type 2: a fundamental dichotomy for all T-cell subsets

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Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation

1 reference

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11 July 2018

High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10.

1 reference

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Differentiation and stability of T helper 1 and 2 cells derived from naive human neonatal CD4+ T cells, analyzed at the single-cell level

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Reversibility of T helper 1 and 2 populations is lost after long-term stimulation

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11 July 2018

Interleukin-12 is produced by dendritic cells and mediates T helper 1 development as well as interferon-gamma production by T helper 1 cells.

1 reference

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Therapy of murine tumors with tumor peptide-pulsed dendritic cells: dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines

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Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo

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Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells

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Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection

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Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood mononuclear cells: priming for IL-12 and tumor necrosis factor alpha production

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In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactions

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Regulation of T cell-dependent and -independent IL-12 production by the three Th2-type cytokines IL-10, IL-6, and IL-4

1 reference

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based on heuristic

inferred from PubMed ID database lookup

IL-12 and mutant P53 peptide-pulsed dendritic cells for the specific immunotherapy of cancer

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal B cells fail to secrete interleukin-12

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leishmania major-infected C3H mice treated with anti-IL-12 mAb develop but do not maintain a Th2 response

1 reference

https://pubmed.ncbi.nlm.nih.gov/9874559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Do B cells drive the diversification of immune responses?

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T and B cell separation by sheep-red-cell rosetting

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endogenous IL-6 and IL-10 contribute to the differentiation of CD40-activated human B lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9874559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9874559

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic susceptibility to Leishmania: IL-12 responsiveness in TH1 cell development

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequential antigen-specific growth of T cells in the T zones and follicles in response to pigeon cytochrome c

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

B cells regulate CD40 ligand-induced IL-12 production in antigen-presenting cells (APC) during T cell/APC interactions

1 reference

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based on heuristic

inferred from PubMed ID database lookup

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10.1084/JEM.189.1.1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9874559%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

release_qqbb7baiwjgq5fuvjdywcim54y

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24 November 2022

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8 December 2019

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9874559%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

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