1-Methyl-4-phenylpyridinium induces synaptic dysfunction through a pathway involving caspase and PKCdelta enzymatic activities. (Q35844507)

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25 December 2019

title

1-Methyl-4-phenylpyridinium induces synaptic dysfunction through a pathway involving caspase and PKCdelta enzymatic activities (English)

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25 December 2019

5

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author name string

Yafell Serulle

1

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25 December 2019

Gerardo Morfini

2

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25 December 2019

Gustavo Pigino

3

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25 December 2019

Jorge E Moreira

4

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25 December 2019

Scott T Brady

6

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25 December 2019

Rodolfo R Llinás

7

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25 December 2019

language of work or name

English

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publication date

7 February 2007

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Proceedings of the National Academy of Sciences of the United States of America

25 December 2019

published in

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volume

104

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25 December 2019

issue

7

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page(s)

2437-2441

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1-Methyl-4-phenylpyridinium affects fast axonal transport by activation of caspase and protein kinase C

25 December 2019

cites work

1 reference

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Toxin-induced models of Parkinson's disease

11 July 2018

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Vesicular reuptake inhibition by a synaptotagmin I C2B domain antibody at the squid giant synapse

11 July 2018

1 reference

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Caspase‐3 dependent proteolytic activation of protein kinase Cδ mediates and regulates 1‐methyl‐4‐phenylpyridinium (MPP+)‐induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration

11 July 2018

1 reference

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Parkinson's disease: mechanisms and models

11 July 2018

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MPTP: insights into parkinsonian neurodegeneration

11 July 2018

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Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease.

11 July 2018

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Thalamocortical dysrhythmia: A neurological and neuropsychiatric syndrome characterized by magnetoencephalography

11 July 2018

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Absence of MPTP-induced neuronal death in mice lacking the dopamine transporter.

11 July 2018

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Inhibition of human caspases by peptide-based and macromolecular inhibitors

11 July 2018

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Peptide inhibitors of caspase-3-like proteases attenuate 1-methyl-4-phenylpyridinum-induced toxicity of cultured fetal rat mesencephalic dopamine neurons

11 July 2018

1 reference

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Protein kinase C delta-specific phosphorylation of the elongation factor eEF-alpha and an eEF-1 alpha peptide at threonine 431.

11 July 2018

1 reference

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Role of the C2B domain of synaptotagmin in vesicular release and recycling as determined by specific antibody injection into the squid giant synapse preterminal.

11 July 2018

1 reference

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Role of the C2A domain of synaptotagmin in transmitter release as determined by specific antibody injection into the squid giant synapse preterminal.

11 July 2018

1 reference

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Presynaptic calcium currents in squid giant synapse.

11 July 2018

1 reference

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Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity

11 July 2018

1 reference

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Caspase-3 activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice

11 July 2018

1 reference

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Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism.

24 September 2018

1 reference

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Elimination of synapses in the developing nervous system

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17287339

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Substrate specificities of caspase family proteases

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17287339

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0611227104

1 reference

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25 December 2019

0 references

1 reference

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25 December 2019

PubMed publication ID

17287339

1 reference