Medical treatments of acute spinal cord injury (Q35846146)

10 August 2017

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1 reference

title

Medical treatments of acute spinal cord injury (English)

1 reference

10 August 2017

W. Young

1

1 reference

PubMed ID

1527532

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1527532

5 October 2022

language of work or name

English

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publication date

1 August 1992

1 reference

PMCID

489197

full work available at URL

10 August 2017

https://europepmc.org/articles/PMC489197

1 reference

PubMed ID

1527532

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1527532

https://europepmc.org/articles/PMC489197?pdf=render

5 October 2022

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

PubMed ID

1527532

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1527532

Journal of Neurology, Neurosurgery and Psychiatry

5 October 2022

published in

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10 August 2017

55

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10 August 2017

8

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10 August 2017

635-639

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Glucocorticoid mechanisms in acute spinal cord injury: a review and therapeutic rationale

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

GM1 ganglioside treatment facilitates behavioral recovery from bilateral brain damage.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

Gangliosides minimize behavioral deficits and enhance structural repair after brain injury.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

Endorphins in experimental spinal injury: Therapeutic effect of naloxone

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

The effect of GM1 ganglioside on coerulospinal, noradrenergic, adult neurons and on fetal monoaminergic neurons transplanted into the transected spinal cord of the adult rat.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

"High-dose" methylprednisolone and CNS injury

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

Novel 21-amino steroids as potent inhibitors of iron-dependent lipid peroxidation.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

Role of lipid peroxidation in post-traumatic spinal cord degeneration: a review.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

Opiate-receptor antagonist nalmefene improves neurological recovery after traumatic spinal cord injury in rats through a central mechanism

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

Effects of the 21-aminosteroid U74006F on posttraumatic spinal cord ischemia in cats

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

Effects of BW755C, a mixed cyclo-oxygenase-lipoxygenase inhibitor, following traumatic spinal cord injury in rats.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

Structure-activity relationships of TRH analogs in rat spinal cord injury

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

Suppression of neurofilament degradation by protease inhibitors in experimental spinal cord injury

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

A pharmacological analysis of the pathophysiological mechanisms of posttraumatic spinal cord ischemia

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

N-methyl-D-aspartate antagonist MK801 improves outcome following traumatic spinal cord injury in rats: behavioral, anatomic, and neurochemical studies

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

A potential role for excitotoxins in the pathophysiology of spinal cord injury

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

TRH analog YM-14673 improves outcome following traumatic brain and spinal cord injury in rats: dose-response studies

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

Opiate antagonist nalmefene improves intracellular free Mg2+, bioenergetic state, and neurologic outcome following traumatic brain injury in rats.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

Comparison of the neuroprotective effects of the N-methyl-D-aspartate antagonist MK-801 and the opiate-receptor antagonist nalmefene in experimental spinal cord ischemia

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

Effects of competitive and non-competitive NMDA receptor antagonists in spinal cord injury

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

Recovery of motor function after spinal-cord injury--a randomized, placebo-controlled trial with GM-1 ganglioside

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

Neurite outgrowth in dorsal root neuronal hybrid clones modulated by ganglioside GM1 and disintegrins

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

Comparison of a Serotonin Antagonist, Opioid Antagonist, and TRH Analog for the Acute Treatment of Experimental Spinal Trauma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

The serotonin antagonist mianserin improves functional recovery following experimental spinal trauma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

Definition of complete spinal cord injury

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

Methylprednisolone or naloxone treatment after acute spinal cord injury: 1-year follow-up data. Results of the second National Acute Spinal Cord Injury Study

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

The neuroprotective pharmacology of methylprednisolone

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

Stimulation of a Ca(2+)-dependent protein kinase by GM1 ganglioside in nerve growth factor-treated PC12 cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

Ganglioside GM1 prevents death induced by excessive excitatory neurotransmission in cultured hippocampal pyramidal neurons

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

GM-1 ganglioside in human spinal cord injury

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

11 July 2018

Commentary on NASCIS-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

Pretreatment with alpha tocopherol enhances neurologic recovery after experimental spinal cord compression injury

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=489197

Evaluation of an intensive methylprednisolone sodium succinate dosing regimen in experimental spinal cord injury

14 November 2018

1 reference

12 December 2020

Methylprednisolone preservation of motor nerve function during early degeneration

1 reference

12 December 2020

A phase I trial of naloxone treatment in acute spinal cord injury

1 reference

12 December 2020

Increase in rat spinal cord blood flow with the calcium channel blocker, nimodipine

1 reference

12 December 2020

Effect of TRH analogs on neurologic recovery after experimental spinal trauma

1 reference

12 December 2020

Acute enhancement of spinal cord synaptosomal (Na+ + K+)-ATPase activity in cats following intravenous methylprednisolone

1 reference

12 December 2020

National acute spinal cord injury study of methylprednisolone or naloxone

1 reference

12 December 2020

Effects of methylprednisolone and the combination of alpha-tocopherol and selenium on arachidonic acid metabolism and lipid peroxidation in traumatized spinal cord tissue

1 reference

12 December 2020

Effects of treatment with U-74006F on neurological outcome following experimental spinal cord injury

1 reference

12 December 2020

Lipid hydrolysis and peroxidation in injured spinal cord: partial protection with methylprednisolone or vitamin E and selenium

1 reference

12 December 2020

Methylprednisolone and neurological function 1 year after spinal cord injury. Results of the National Acute Spinal Cord Injury Study

1 reference

12 December 2020

The value of postural reduction in the initial management of closed injuries of the spine with paraplegia and tetraplegia

1 reference

12 December 2020

Correlation of methylprednisolone levels in cat spinal cord with its effects on (Na+ + K+)-ATPase, lipid peroxidation, and alpha motor neuron function

1 reference

12 December 2020

Effects of intravenous methylprednisolone on spinal cord lipid peroxidation and Na+ + K+)-ATPase activity. Dose-response analysis during 1st hour after contusion injury in the cat

1 reference

12 December 2020

Efficacy of Methylprednisolone in Acute Spinal Cord Injury

1 reference

12 December 2020

The free radical pathology and the microcirculation in the major central nervous system disorders

1 reference

12 December 2020

Effect of naloxone on posttraumatic ischemia in experimental spinal contusion

1 reference

12 December 2020

Comparison of thyrotropin-releasing hormone (TRH), naloxone, and dexamethasone treatments in experimental spinal injury

1 reference

12 December 2020

Comparison of naloxone and a delta-selective antagonist in experimental spinal stroke

1 reference

12 December 2020

Experimental spinal cord injury: treatment with naloxone

1 reference

12 December 2020

Effect of methylprednisolone on motor function and spinal cord blood flow after spinal cord compression in rats

1 reference

12 December 2020

Pharmacological therapy of acute spinal cord injury: studies of high dose methylprednisolone and naloxone

1 reference

12 December 2020

Morphometric assessment of drug effects in experimental spinal cord injury

1 reference

12 December 2020

Effect of high-dose corticosteroid therapy on blood flow, evoked potentials, and extracellular calcium in experimental spinal injury

1 reference

12 December 2020

Effect of methylprednisolone in compression trauma to the feline spinal cord

1 reference

12 December 2020

Identifiers

DOI

10.1136/JNNP.55.8.635

1 reference

10 August 2017

1 reference

10 August 2017

1 reference

PMCID

489197