Increased tumor cell dissemination and cellular senescence in the absence of beta1-integrin function (Q35846812)

10 August 2017

Increased tumor cell dissemination and cellular senescence in the absence of beta1-integrin function (English)

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10 August 2017

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7

Reinhard Fässler

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10 August 2017

Angelika Kren

1

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10 August 2017

Vanessa Baeriswyl

2

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10 August 2017

François Lehembre

3

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10 August 2017

Christoph Wunderlin

4

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10 August 2017

Karin Strittmatter

5

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10 August 2017

Helena Antoniadis

6

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10 August 2017

Ugo Cavallaro

8

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10 August 2017

Gerhard Christofori

9

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10 August 2017

language of work or name

English

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publication date

31 May 2007

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10 August 2017

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10 August 2017

26

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10 August 2017

12

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10 August 2017

2832-2842

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describes a project that uses

10 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1894776/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Ablation of beta1 integrin in mammary epithelium reveals a key role for integrin in glandular morphogenesis and differentiation.

1 reference

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Beta1 integrins regulate mammary gland proliferation and maintain the integrity of mammary alveoli

11 July 2018

1 reference

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Integrin signalling during tumour progression

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894776

Distinct ligand binding sites in integrin α3β1 regulate matrix adhesion and cell–cell contact

11 July 2018

1 reference

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Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by alpha v beta 3 and alpha 5 beta 1 integrins

11 July 2018

1 reference

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Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts

11 July 2018

1 reference

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Integrins: bidirectional, allosteric signaling machines

11 July 2018

1 reference

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Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex

11 July 2018

1 reference

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Molecular complexity and dynamics of cell-matrix adhesions

11 July 2018

1 reference

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Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins

11 July 2018

1 reference

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Reduced expression of neural cell adhesion molecule induces metastatic dissemination of pancreatic beta tumor cells.

11 July 2018

1 reference

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LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan

11 July 2018

1 reference

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Neural cell adhesion molecule (N-CAM) is required for cell type segregation and normal ultrastructure in pancreatic islets

11 July 2018

1 reference

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beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes

11 July 2018

1 reference

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Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways

11 July 2018

1 reference

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11 July 2018

Integrins and anoikis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894776

Beta 1 integrin is essential for teratoma growth and angiogenesis

11 July 2018

1 reference

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Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894776

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894776

p21 is a universal inhibitor of cyclin kinases

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894776

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

11 July 2018

1 reference

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Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894776

Consequences of lack of beta 1 integrin gene expression in mice

11 July 2018

1 reference

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Requirement of vascular integrin alpha v beta 3 for angiogenesis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894776

Flow cytometric estimation of DNA and RNA content in intact cells stained with hoechst 33342 and pyronin Y

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894776

Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894776

Pericytes limit tumor cell metastasis

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894776

Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894776

Inhibition of integrin linked kinase (ILK) suppresses beta-catenin-Lef/Tcf-dependent transcription and expression of the E-cadherin repressor, snail, in APC-/- human colon carcinoma cells

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894776

Cadherins regulate aggregation of pancreatic beta-cells in vivo.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894776

Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894776

Fetal and adult hematopoietic stem cells require beta1 integrin function for colonizing fetal liver, spleen, and bone marrow

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894776

Loss of Neural Cell Adhesion Molecule Induces Tumor Metastasis by Up-regulating Lymphangiogenesis

22 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894776

N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling

6 December 2018

1 reference

12 December 2020

Definition of Two Angiogenic Pathways by Distinct alpha(v) Integrins

1 reference

12 December 2020

p21Waf1/Cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53

1 reference

12 December 2020

Opinion: emerging mechanisms of tumour lymphangiogenesis and lymphatic metastasis

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.EMBOJ.7601738

1 reference

10 August 2017

1 reference

10 August 2017

1 reference