Insertion of primary syncytium-inducing (SI) and non-SI envelope V3 loops in human immunodeficiency virus type 1 (HIV-1) LAI reduces neutralization sensitivity to autologous, but not heterologous, HIV-1 antibodies (Q35848446)

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scientific article published in October 1995

Language	Label	Description	Also known as
English	Insertion of primary syncytium-inducing (SI) and non-SI envelope V3 loops in human immunodeficiency virus type 1 (HIV-1) LAI reduces neutralization sensitivity to autologous, but not heterologous, HIV-1 antibodies	scientific article published in October 1995

Statements

scholarly article

1 reference

Europe PubMed Central

10 August 2017

Insertion of primary syncytium-inducing (SI) and non-SI envelope V3 loops in human immunodeficiency virus type 1 (HIV-1) LAI reduces neutralization sensitivity to autologous, but not heterologous, HIV-1 antibodies (English)

1 reference

Europe PubMed Central

10 August 2017

author name string

Hogervorst E

1

1 reference

Europe PubMed Central

10 August 2017

de Jong J

2

1 reference

Europe PubMed Central

10 August 2017

van Wijk A

3

1 reference

Europe PubMed Central

10 August 2017

Bakker M

4

1 reference

Europe PubMed Central

10 August 2017

Valk M

5

1 reference

Europe PubMed Central

10 August 2017

Nara P

6

1 reference

Europe PubMed Central

10 August 2017

Goudsmit J

7

1 reference

Europe PubMed Central

10 August 2017

language of work or name

0 references

publication date

1 October 1995

1 reference

Europe PubMed Central

10 August 2017

Journal of Virology

1 reference

Europe PubMed Central

10 August 2017

69

1 reference

Europe PubMed Central

10 August 2017

10

1 reference

Europe PubMed Central

10 August 2017

6342-6351

1 reference

Europe PubMed Central

10 August 2017

Effect of amino acid changes in the V1/V2 region of the human immunodeficiency virus type 1 gp120 glycoprotein on subunit association, syncytium formation, and recognition by a neutralizing antibody.

1 reference

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Selection for specific sequences in the external envelope protein of human immunodeficiency virus type 1 upon primary infection

1 reference

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Two mechanisms of soluble CD4 (sCD4)-mediated inhibition of human immunodeficiency virus type 1 (HIV-1) infectivity and their relation to primary HIV-1 isolates with reduced sensitivity to sCD4.

1 reference

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Mutations in human immunodeficiency virus type 1 gp41 affect sensitivity to neutralization by gp120 antibodies.

1 reference

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Genotypic and phenotypic characterization of HIV-1 patients with primary infection

1 reference

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V3 loop of the human immunodeficiency virus type 1 Env protein: interpreting sequence variability.

1 reference

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Adaptation of two primary human immunodeficiency virus type 1 isolates to growth in transformed T cell lines correlates with alterations in the responses of their envelope glycoproteins to soluble CD4.

1 reference

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Two antigenically distinct subtypes of human immunodeficiency virus type 1: viral genotype predicts neutralization serotype

1 reference

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Neutralization sensitivity of human immunodeficiency virus type 1 is determined in part by the cell in which the virus is propagated.

1 reference

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Cryptic nature of envelope V3 region epitopes protects primary monocytotropic human immunodeficiency virus type 1 from antibody neutralization

1 reference

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Macrophage-tropic and T-cell line-adapted chimeric strains of human immunodeficiency virus type 1 differ in their susceptibilities to neutralization by soluble CD4 at different temperatures.

1 reference

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Development of the anti-gp120 antibody response during seroconversion to human immunodeficiency virus type 1

1 reference

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Frequent and early HIV-1MN neutralizing capacity in sera from Dutch HIV-1 seroconverters is related to antibody reactivity to peptides from the gp120 V3 domain

1 reference

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11 July 2018

Equal levels of gp120 retention and neutralization resistance of phenotypically distinct primary human immunodeficiency virus type 1 variants upon soluble CD4 treatment

1 reference

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Adaptation to persistent growth in the H9 cell line renders a primary isolate of human immunodeficiency virus type 1 sensitive to neutralization by vaccine sera

1 reference

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Syncytium-inducing and non-syncytium-inducing capacity of human immunodeficiency virus type 1 subtypes other than B: phenotypic and genotypic characteristics. WHO Network for HIV Isolation and Characterization

1 reference

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Similarity in env and gag genes between genomic RNAs of human immunodeficiency virus type 1 (HIV-1) from mother and infant is unrelated to time of HIV-1 RNA positivity in the child.

1 reference

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11 July 2018

Syncytium-inducing (SI) phenotype suppression at seroconversion after intramuscular inoculation of a non-syncytium-inducing/SI phenotypically mixed human immunodeficiency virus population.

1 reference

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Evidence for coinfection by multiple strains of human immunodeficiency virus type 1 subtype B in an acute seroconvertor.

1 reference

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Increase in sensitivity to soluble CD4 by primary HIV type 1 isolates after passage through C8166 cells: association with sequence differences in the first constant (C1) region of glycoprotein 120.

1 reference

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11 July 2018

Immunochemical analysis of the gp120 surface glycoprotein of human immunodeficiency virus type 1: probing the structure of the C4 and V4 domains and the interaction of the C4 domain with the V3 loop

1 reference

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Antibodies to discontinuous or conformationally sensitive epitopes on the gp120 glycoprotein of human immunodeficiency virus type 1 are highly prevalent in sera of infected humans

1 reference

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11 July 2018

Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120.

1 reference

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Alteration of V3 loop context within the envelope of human immunodeficiency virus type 1 enhances neutralization

1 reference

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V3 variability can influence the ability of an antibody to neutralize or enhance infection by diverse strains of human immunodeficiency virus type 1

1 reference

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A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences

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Failure of a human immunodeficiency virus (HIV) immune globulin to protect chimpanzees against experimental challenge with HIV

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Numbers of CD4+ cells and the levels of core antigens of and antibodies to the human immunodeficiency virus as predictors of AIDS among seropositive homosexual men.

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Antibody-dependent enhancement of human immunodeficiency virus type 1 infection

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Loss of envelope antigens of HTLV-III/LAV, a factor in AIDS pathogenesis?

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Complete nucleotide sequence of the AIDS virus, HTLV-III

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Linear versus conformational variation of V3 neutralization domains of HIV-1 during experimental and natural infection

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Human immunodeficiency virus type 1 neutralization epitope with conserved architecture elicits early type-specific antibodies in experimentally infected chimpanzees

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Antibodies that inhibit fusion of human immunodeficiency virus-infected cells bind a 24-amino acid sequence of the viral envelope, gp120

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Type-specific neutralization of the human immunodeficiency virus with antibodies to env-encoded synthetic peptides

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Shedding and interspecies type sero-reactivity of the envelope glycopolypeptide gp120 of the human immunodeficiency virus

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High concentrations of recombinant soluble CD4 are required to neutralize primary human immunodeficiency virus type 1 isolates

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Emergence of viruses resistant to neutralization by V3-specific antibodies in experimental human immunodeficiency virus type 1 IIIB infection of chimpanzees.

1 reference

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Dissociation of gp120 from HIV-1 virions induced by soluble CD4.

1 reference

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Immunodominance and antigenic variation of the principal neutralization domain of HIV-1.

1 reference

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Production of site-selected neutralizing human monoclonal antibodies against the third variable domain of the human immunodeficiency virus type 1 envelope glycoprotein

1 reference

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Discontinuous sequence change of human immunodeficiency virus (HIV) type 1 env sequences in plasma viral and lymphocyte-associated proviral populations in vivo: implications for models of HIV pathogenesis.

1 reference

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Neutralizing activity of anti-peptide antibodies against the principal neutralization domain of human immunodeficiency virus type 1.

1 reference

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Differential loss of envelope glycoprotein gp120 from virions of human immunodeficiency virus type 1 isolates: effects on infectivity and neutralization

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Resistance of primary isolates of human immunodeficiency virus type 1 to soluble CD4 is independent of CD4-rgp120 binding affinity

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The role of the V3 loop of gp120 in HIV infection.

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Prevention of HIV infection by passive immunization with HIV immunoglobulin

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Resistance of primary isolates of human immunodeficiency virus type 1 to neutralization by soluble CD4 is not due to lower affinity with the viral envelope glycoprotein gp120

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Human immunodeficiency virus type 1 clones chimeric for the envelope V3 domain differ in syncytium formation and replication capacity

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Neutralization of Divergent HIV-1 Isolates by Conformation-Dependent Human Antibodies to Gp120

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Conformational epitope on gp120 important in CD4 binding and human immunodeficiency virus type 1 neutralization identified by a human monoclonal antibody

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Epitopes recognized by the neutralizing antibodies of an HIV-1-infected individual

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Rapid and simple method for purification of nucleic acids

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Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-1LAI, HIV-1MAL, and HIV-1ELI.

1 reference

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Naturally occurring mutations within HIV-1 V3 genomic RNA lead to antigenic variation dependent on a single amino acid substitution

1 reference

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Evolution of the V3 envelope domain in proviral sequences and isolates of human immunodeficiency virus type 1 during transition of the viral biological phenotype

1 reference

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Convergent and divergent sequence evolution in the surface envelope glycoprotein of human immunodeficiency virus type 1 within a single infected patient

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Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule

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HIV-1 biological phenotype in long-term infected individuals evaluated with an MT-2 cocultivation assay

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Minimal requirements for the human immunodeficiency virus type 1 V3 domain to support the syncytium-inducing phenotype: analysis by single amino acid substitution

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Identification and characterization of a neutralization site within the second variable region of human immunodeficiency virus type 1 gp120

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An N-glycan within the human immunodeficiency virus type 1 gp120 V3 loop affects virus neutralization

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Neutralizing antibody responses to autologous and heterologous isolates of human immunodeficiency virus

1 reference

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Genetic variation in AIDS viruses

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Conserved sequence and structural elements in the HIV-1 principal neutralizing determinant

1 reference

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The majority of neutralizing Abs in HIV-1-infected patients recognize linear V3 loop sequences. Studies using HIV-1MN multiple antigenic peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/7666535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the specificity of the human antibody response to the V3 neutralization domain of HIV-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/7666535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The reactivities of HIV-1+ human sera with solid-phase V3 loop peptides can be poor predictors of their reactivities with V3 loops on native gp120 molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/7666535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of HIV-1-neutralising and syncytium-inhibiting antibodies in uninfected recipients of HIV-1IIIB rgp120 subunit vaccine

1 reference

https://pubmed.ncbi.nlm.nih.gov/7666535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of infectivity of a non-syncytium inducing HIV-1 by sCD4 and by human antibodies that neutralize syncytium inducing HIV-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/7666535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Jitters jeopardize AIDS vaccine trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/7666535

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.69.10.6342-6351.1995

0 references

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

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