Differential gene expression, GATA1 target genes, and the chemotherapy sensitivity of Down syndrome megakaryocytic leukemia. (Q35848677)

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8 January 2020

title

Differential gene expression, GATA1 target genes, and the chemotherapy sensitivity of Down syndrome megakaryocytic leukemia (English)

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8 January 2020

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8 January 2020

Ravikiran S Yedidi

5

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author name string

Yubin Ge

1

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8 January 2020

Katherine M LaFiura

3

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Dana Tatman

4

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Mark L Stout

6

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8 January 2020

Steven A Buck

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Gita Massey

8

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David L Becton

9

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Howard J Weinstein

10

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Yaddanapudi Ravindranath

11

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Larry H Matherly

12

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Jeffrey W Taub

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language of work or name

English

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publication date

25 October 2005

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8 January 2020

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8 January 2020

volume

107

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8 January 2020

issue

4

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page(s)

1570-1581

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GATA1, cytidine deaminase, and the high cure rate of Down syndrome children with acute megakaryocytic leukemia.

8 January 2020

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1 reference

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Down syndrome, drug metabolism and chromosome 21.

11 July 2018

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The role of cytidine deaminase and GATA1 mutations in the increased cytosine arabinoside sensitivity of Down syndrome myeloblasts and leukemia cell lines

11 July 2018

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Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21

11 July 2018

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GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome

11 July 2018

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Transcriptional regulation of the cystathionine-beta -synthase gene in Down syndrome and non-Down syndrome megakaryocytic leukemia cell lines

11 July 2018

1 reference

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Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome

11 July 2018

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Acute myeloid leukemia cells are protected from spontaneous and drug-induced apoptosis by direct contact with a human bone marrow stromal cell line (HS-5).

11 July 2018

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Molecular cloning and characterization of a surface antigen preferentially overexpressed on multiple myeloma cells

11 July 2018

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Distinctive demography, biology, and outcome of acute myeloid leukemia and myelodysplastic syndrome in children with Down syndrome: Children's Cancer Group Studies 2861 and 2891.

11 July 2018

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Myelodysplasia and acute megakaryoblastic leukemia in Down's syndrome

11 July 2018

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Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth

11 July 2018

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Growth and development of haemopoietic cells: a deterministic process?

11 July 2018

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AML patients with Down syndrome have a high cure rate with AML-BFM therapy with reduced dose intensity

11 July 2018

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Distinct gene expression patterns in a tamoxifen-sensitive human mammary carcinoma xenograft and its tamoxifen-resistant subline MaCa 3366/TAM.

24 September 2018

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Gene expression profiling of pediatric acute myelogenous leukemia

24 September 2018

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Microarray transcript profiling distinguishes the transient from the acute type of megakaryoblastic leukaemia (M7) in Down's syndrome, revealing PRAME as a specific discriminating marker.

24 September 2018

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Prognostically useful gene-expression profiles in acute myeloid leukemia.

24 September 2018

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The GATA1 mutation in an adult patient with acute megakaryoblastic leukemia not accompanying Down syndrome.

24 September 2018

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Increased age at diagnosis has a significantly negative effect on outcome in children with Down syndrome and acute myeloid leukemia: a report from the Children's Cancer Group Study 2891.

24 September 2018

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12 December 2020

Mutagenesis of GATA1 is an initiating event in Down syndrome leukemogenesis

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12 December 2020

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12 December 2020

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Expression of chromosome 21-localized genes in acute myeloid leukemia: differences between Down syndrome and non-Down syndrome blast cells and relationship to in vitro sensitivity to cytosine arabinoside and daunorubicin

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Identifiers

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8 January 2020

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