Induction of susceptibility to tumor necrosis factor by E1A is dependent on binding to either p300 or p105-Rb and induction of DNA synthesis (Q35853222)

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scientific article published in January 1996

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English	Induction of susceptibility to tumor necrosis factor by E1A is dependent on binding to either p300 or p105-Rb and induction of DNA synthesis	scientific article published in January 1996

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13 October 2019

Induction of susceptibility to tumor necrosis factor by E1A is dependent on binding to either p300 or p105-Rb and induction of DNA synthesis (English)

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13 October 2019

Penelope Duerksen-Hughes

2

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13 October 2019

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J Shisler

1

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13 October 2019

T M Hermiston

3

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13 October 2019

W S Wold

4

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13 October 2019

L R Gooding

5

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13 October 2019

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1 January 1996

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13 October 2019

Journal of Virology

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13 October 2019

70

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13 October 2019

1

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13 October 2019

68-77

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13 October 2019

Domains of E1A that bind p105Rb, p130, and p300 are required to block nerve growth factor-induced neurite growth in PC12 cells

1 reference

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Integration of cell cycle control with transcriptional regulation by the retinoblastoma protein

1 reference

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11 July 2018

p300, and p300-associated proteins, are components of TATA-binding protein (TBP) complexes.

1 reference

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DNA tumor virus transforming proteins and the cell cycle

1 reference

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A region in the C-terminus of adenovirus 2/5 E1a protein is required for association with a cellular phosphoprotein and important for the negative modulation of T24-ras mediated transformation, tumorigenesis and metastasis

1 reference

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Augmentation by IL-1 alpha of tumor necrosis factor-alpha cytotoxicity in cells transfected with adenovirus E1A.

1 reference

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Identification of specific adenovirus E1A N-terminal residues critical to the binding of cellular proteins and to the control of cell growth

1 reference

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Tumor necrosis factor in the pathogenesis of infectious diseases

1 reference

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Tumor necrosis factor: an updated review of its biology.

1 reference

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Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

1 reference

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Regulation of MyoD gene transcription and protein function by the transforming domains of the adenovirus E1A oncoprotein.

1 reference

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11 July 2018

Cloning of a new member of the retinoblastoma gene family (pRb2) which binds to the E1A transforming domain

1 reference

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11 July 2018

Speculations on the roles of RB1 in tissue-specific differentiation, tumor initiation, and tumor progression.

1 reference

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11 July 2018

Tumor necrosis factor, other cytokines and disease

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11 July 2018

The zinc finger region of the adenovirus E1A transactivating domain complexes with the TATA box binding protein

1 reference

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11 July 2018

Tumor necrosis factor alpha promotes replication and pathogenicity of rat cytomegalovirus.

1 reference

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11 July 2018

The immediate early genes of human cytomegalovirus upregulate tumor necrosis factor-alpha gene expression

1 reference

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11 July 2018

The adenovirus E1A 12S product displays functional redundancy in activating the human proliferating cell nuclear antigen promoter

1 reference

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11 July 2018

Complementary functions of E1a conserved region 1 cooperate with conserved region 3 to activate adenovirus serotype 5 early promoters

1 reference

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11 July 2018

Influenza A virus replication is inhibited by tumor necrosis factor-alpha in vitro

1 reference

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11 July 2018

The retinoblastoma protein: more than a tumor suppressor

1 reference

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11 July 2018

Regulation of TNF-mediated cell death and inflammation by human adenoviruses.

1 reference

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11 July 2018

The retinoblastoma protein and cell cycle control

1 reference

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11 July 2018

The N-terminal region of the adenovirus type 5 E1A proteins can repress expression of cellular genes via two distinct but overlapping domains

1 reference

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11 July 2018

Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor

1 reference

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Virus strategies for evasion of the host response to infection

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11 July 2018

Adenovirus-induced alterations of the cell growth cycle: a requirement for expression of E1A but not of E1B.

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Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

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Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter

1 reference

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Isolation of a transforming sequence from a human bladder carcinoma cell line

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Adenovirus early region 1A protein activates transcription of a nonviral gene introduced into mammalian cells by infection or transfection

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11 July 2018

Transformation properties of type 5 adenovirus mutants that differentially express the E1A gene products

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11 July 2018

Activation of human polymorphonuclear neutrophil functions by interferon-gamma and tumor necrosis factors

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11 July 2018

Monoclonal antibodies specific for adenovirus early region 1A proteins: extensive heterogeneity in early region 1A products

1 reference

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11 July 2018

Transformation by human adenoviruses

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Measurement of protein using bicinchoninic acid

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A 14,700 MW protein from the E3 region of adenovirus inhibits cytolysis by tumor necrosis factor

1 reference

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11 July 2018

Identification of separate domains in the adenovirus E1A gene for immortalization activity and the activation of virus early genes

1 reference

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11 July 2018

Repression of the immunoglobulin heavy chain enhancer by the adenovirus-2 E1A products.

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11 July 2018

Mapping of cellular protein-binding sites on the products of early-region 1A of human adenovirus type 5.

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11 July 2018

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

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11 July 2018

Interactions between cell growth-regulating domains in the products of the adenovirus E1A oncogene

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Adenovirus E1A products suppress myogenic differentiation and inhibit transcription from muscle-specific promoters

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Use of deletion and point mutants spanning the coding region of the adenovirus 5 E1A gene to define a domain that is essential for transcriptional activation

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Induction by E1A oncogene expression of cellular susceptibility to lysis by TNF.

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Induction of cell cycle progression by adenovirus E1A gene 13S- and 12S-mRNA products in quiescent rat cells

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Differential splicing yields novel adenovirus 5 E1A mRNAs that encode 30 kd and 35 kd proteins

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Repression of insulin gene expression by adenovirus type 5 E1a proteins

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Expression of adenovirus E1B mutant phenotypes is dependent on the host cell and on synthesis of E1A proteins

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Functions of adenovirus E1A.

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Different functional domains of the adenovirus E1A gene are involved in regulation of host cell cycle products

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Cytotoxicity by tumor necrosis factor is linked with the cell cycle but does not require DNA synthesis

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Adenovirus E1A renders infected cells sensitive to cytolysis by tumor necrosis factor

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Insulin gene enhancer activity is inhibited by adenovirus 5 E1a gene products

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Cellular targets for transformation by the adenovirus E1A proteins

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Tumour necrosis factors alpha and beta inhibit virus replication and synergize with interferons

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Adenovirus E1A represses protease gene expression and inhibits metastasis of human tumor cells.

1 reference

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Analysis of E1A-mediated growth regulation functions: binding of the 300-kilodalton cellular product correlates with E1A enhancer repression function and DNA synthesis-inducing activity

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Induction of sensitivity to the cytotoxic action of tumor necrosis factor alpha by adenovirus E1A is independent of transformation and transcriptional activation

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Retinoblastoma growth suppressor and a 300-kDa protein appear to regulate cellular DNA synthesis

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Adenovirus E1A activation domain binds the basic repeat in the TATA box transcription factor

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Requirement of the adenovirus E1A transformation domain 1 for inhibition of PC12 cell neuronal differentiation

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E1A induces phosphorylation of the retinoblastoma protein independently of direct physical association between the E1A and retinoblastoma products

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The 10,400- and 14,500-dalton proteins encoded by region E3 of adenovirus function together to protect many but not all mouse cell lines against lysis by tumor necrosis factor

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Role of E2F transcription factor in E1A-mediated trans activation of cellular genes

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Independent transformation activity by adenovirus-5 E1A-conserved regions 1 or 2 mutants.

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Human cyclin A and the retinoblastoma protein interact with similar but distinguishable sequences in the adenovirus E1A gene product

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11 July 2018

Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor

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Tumor necrosis factor. Characterization at the molecular, cellular and in vivo level

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Adenovirus E1A makes two distinct contacts with the retinoblastoma protein

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Effects of Ad5 E1A mutant viruses on the cell cycle in relation to the binding of cellular proteins including the retinoblastoma protein and cyclin A

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11 July 2018

The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins

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Ability of adenovirus 5 E1A proteins to suppress differentiation of BC3H1 myoblasts correlates with their binding to a 300 kDa cellular protein

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E2F: a link between the Rb tumor suppressor protein and viral oncoproteins

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Promoter-specific trans-activation by the adenovirus E1A12S product involves separate E1A domains

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Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins

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11 July 2018

Retinoblastoma protein switches the E2F site from positive to negative element

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Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells

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Tumor necrosis factor-alpha induction by reovirus serotype 3.

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24 September 2018

Arachidonic acid-selective cytosolic phospholipase A2 is crucial in the cytotoxic action of tumor necrosis factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189789

24 September 2018

Partial transformation of primary rat cells by the leftmost 4.5% fragment of adenovirus 5 DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189789

24 September 2018

Adenovirus 2 early region 1A stimulates expression of both viral and cellular genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189789

24 September 2018

Antiviral effects of recombinant tumour necrosis factor in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189789

24 September 2018

Functional interactions within adenovirus E1A protein complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8523594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of apoptosis by adenovirus type 5 E1A in rat cells requires a proliferation block

1 reference

https://pubmed.ncbi.nlm.nih.gov/8523594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenovirus 5 E1A proteins disrupt the neuronal phenotype and growth factor responsiveness of PC12 cells by a conserved region 1-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/8523594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple pathways for gene activation in rodent cells by the smaller adenovirus 5 E1A protein and their relevance to growth and transformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8523594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

E1A-associated p300 and CREB-associated CBP belong to a conserved family of coactivators

1 reference

https://pubmed.ncbi.nlm.nih.gov/8523594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An N-terminal region of adenovirus E1a essential for cell transformation and induction of an epithelial cell growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/8523594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of p34, the mammalian homolog of the yeast cdc2+/CDC28 protein kinase, is stimulated during adenovirus-induced proliferation of primary baby rat kidney cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8523594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8523594%20AND%20SRC:MED&resulttype=core&format=json

13 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8523594%20AND%20SRC:MED&resulttype=core&format=json

13 October 2019

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