Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors (Q35853278)

10 August 2017

Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors (English)

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10 August 2017

Read M

1

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10 August 2017

Harrison RJ

2

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10 August 2017

Romagnoli B

3

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10 August 2017

Tanious FA

4

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10 August 2017

Gowan SH

5

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10 August 2017

Reszka AP

6

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10 August 2017

Wilson WD

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10 August 2017

Kelland LR

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10 August 2017

Neidle S

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10 August 2017

language of work or name

English

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publication date

17 April 2001

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Proceedings of the National Academy of Sciences of the United States of America

10 August 2017

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10 August 2017

98

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10 August 2017

9

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10 August 2017

4844-4849

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Telomere maintenance by recombination in human cells.

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33125

Telomeres and their control

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33125

Structural characterization of a guanine-quadruplex ligand complex

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33125

Structure-activity relationships among guanine-quadruplex telomerase inhibitors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33125

Telomerase as an anti-cancer target: current status and future prospects.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33125

Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33125

Telomere shortening and apoptosis in telomerase-inhibited human tumor cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33125

Creation of human tumour cells with defined genetic elements

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33125

2,7-Disubstituted amidofluorenone derivatives as inhibitors of human telomerase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33125

Telomerase and the maintenance of chromosome ends

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33125

Mammalian telomeres end in a large duplex loop

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33125

Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33125

NMR-Based model of a telomerase-inhibiting compound bound to G-quadruplex DNA.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33125

Fluorescent dyes specific for quadruplex DNA

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33125

The crystal structure of a parallel-stranded guanine tetraplex at 0.95 A resolution

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33125

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33125

Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33125

G-quartet structures in telomeric DNA.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33125

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33125

Telomeres shorten during ageing of human fibroblasts

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33125

Inhibition of telomerase by G-quartet DNA structures

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33125

Inhibition of telomerase limits the growth of human cancer cells.

11 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.081560598

A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.081560598

Development and use of quantum mechanical molecular models. 76. AM1: a new general purpose quantum mechanical molecular model

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.081560598

Telomere states and cell fates

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.081560598

G-quadruplex DNA: a target for drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.081560598

Inhibition of human telomerase by a G-quadruplex-interactive compound

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.081560598

Human telomerase inhibition by substituted acridine derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.081560598

Molecular modeling studies on G-quadruplex complexes of telomerase inhibitors: structure-activity relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.081560598

Inhibition of unwinding of G-quadruplex structures by Sgs1 helicase in the presence of N,N'-bis[2-(1-piperidino)ethyl]-3,4,9,10-perylenetetracarboxylic diimide, a G-quadruplex-interactive ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.081560598

The Bloom's syndrome helicase unwinds G4 DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.081560598

21 January 2018

Identifiers

DOI

10.1073/PNAS.081560598

1 reference

10 August 2017

0 references

1 reference

10 August 2017

PubMed publication ID

11309493

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