Initial testing of JNJ-26854165 (Serdemetan) by the pediatric preclinical testing program. (Q35857060)

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12 February 2020

title

Initial testing of JNJ-26854165 (Serdemetan) by the pediatric preclinical testing program (English)

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2

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Richard B Lock

4

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C P Reynolds

9

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Min H Kang

10

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15

Peter J Houghton

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6

John M Maris

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1

Malcolm A Smith

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14

Raushan T Kurmasheva

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3

E Anders Kolb

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7

Stephen T Keir

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5

Hernan Carol

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author name string

Christopher L Morton

8

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Janine Arts

11

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Tarig Bashir

12

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Michel Janicot

13

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publication date

15 September 2011

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12 February 2020

published in

Pediatric Blood Cancer

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volume

59

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page(s)

329-332

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issue

2

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Nutlin-3a is a potential therapeutic for ewing sarcoma

12 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504194

The novel tryptamine derivative JNJ-26854165 induces wild-type p53- and E2F1-mediated apoptosis in acute myeloid and lymphoid leukemias

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504194

Restoration of p53 pathway by nutlin-3 induces cell cycle arrest and apoptosis in human rhabdomyosarcoma cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504194

MDM2 antagonist nutlin-3 is a potent inducer of apoptosis in pediatric acute lymphoblastic leukemia cells with wild-type p53 and overexpression of MDM2.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504194

A fluorescence microplate cytotoxicity assay with a 4-log dynamic range that identifies synergistic drug combinations

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504194

Small-molecule MDM2 antagonists as a new therapy concept for neuroblastoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504194

Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504194

Small-molecule antagonists of p53-MDM2 binding: research tools and potential therapeutics.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504194

Characterization of childhood acute lymphoblastic leukemia xenograft models for the preclinical evaluation of new therapies

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504194

Experimental chemotherapy of human medulloblastoma cell lines and transplantable xenografts with bifunctional alkylating agents

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4504194

MDM2 inhibition sensitizes neuroblastoma to chemotherapy-induced apoptotic cell death

27 July 2018

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Crossref

https://api.crossref.org/works/10.1002%2FPBC.23319

The pediatric preclinical testing program: description of models and early testing results.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FPBC.23319

21 January 2018

Identifiers

DOI

10.1002/PBC.23319

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