TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice (Q35858105)

10 August 2017

TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice (English)

1 reference

10 August 2017

0 references

0 references

Christian K Holm

3

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Frederik Dagnæs-Hansen

Frederik Dagnæs-Hansen

6

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Trevor Owens

Trevor Owens

10

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Allan Randrup Thomsen

Allan R Thomsen

12

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Søren Riis Paludan

13

Søren R Paludan

1 reference

10 August 2017

1

Line S Reinert

1 reference

10 August 2017

Louis Harder

2

1 reference

10 August 2017

Marie B Iversen

4

1 reference

10 August 2017

Kristy A Horan

5

1 reference

10 August 2017

Benedicte P Ulhøi

7

1 reference

10 August 2017

Thomas H Holm

8

1 reference

10 August 2017

Trine H Mogensen

9

1 reference

10 August 2017

Jens R Nyengaard

11

1 reference

10 August 2017

language of work or name

English

0 references

publication date

19 March 2012

1 reference

Journal of Clinical Investigation

10 August 2017

1 reference

10 August 2017

122

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10 August 2017

1368-1376

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10 August 2017

4

1 reference

describes a project that uses

10 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3314467/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity

1 reference

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Recognition of herpesviruses by the innate immune system

11 July 2018

1 reference

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IFI16 is an innate immune sensor for intracellular DNA

11 July 2018

1 reference

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Interferon lambda inhibits herpes simplex virus type I infection of human astrocytes and neurons

11 July 2018

1 reference

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Human TRAF3 adaptor molecule deficiency leads to impaired Toll-like receptor 3 response and susceptibility to herpes simplex encephalitis

11 July 2018

1 reference

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Pattern recognition receptors and inflammation

11 July 2018

1 reference

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RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

11 July 2018

1 reference

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RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate

11 July 2018

1 reference

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Toll-Like Receptor 3 Has a Protective Role against West Nile Virus Infection

11 July 2018

1 reference

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An important role for type III interferon (IFN-lambda/IL-28) in TLR-induced antiviral activity

11 July 2018

1 reference

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TLR3 deficiency in patients with herpes simplex encephalitis

11 July 2018

1 reference

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Innate recognition network driving herpes simplex virus-induced corneal immunopathology: role of the toll pathway in early inflammatory events in stromal keratitis

11 July 2018

1 reference

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Astrocyte indoleamine 2,3-dioxygenase is induced by the TLR3 ligand poly(I:C): mechanism of induction and role in antiviral response

11 July 2018

1 reference

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DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

11 July 2018

1 reference

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Lethal encephalitis in myeloid differentiation factor 88-deficient mice infected with herpes simplex virus 1.

11 July 2018

1 reference

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Preferential expression and function of Toll-like receptor 3 in human astrocytes

11 July 2018

1 reference

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Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis

11 July 2018

1 reference

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Herpes simplex virus infections of the central nervous system: encephalitis and meningitis, including Mollaret's

11 July 2018

1 reference

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Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection

11 July 2018

1 reference

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Role of indoleamine-2,3-dioxygenase in alpha/beta and gamma interferon-mediated antiviral effects against herpes simplex virus infections.

11 July 2018

1 reference

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Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis

11 July 2018

1 reference

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Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314467

Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency

11 July 2018

1 reference

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CD8(+) T cells can block herpes simplex virus type 1 (HSV-1) reactivation from latency in sensory neurons

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314467

Role of NK cells in protection of mice against herpes simplex virus-1 infection.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314467

Cutting edge: priming of CD8 T cell immunity to herpes simplex virus type 1 requires cognate TLR3 expression in vivo

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314467

TLR2 and TLR9 synergistically control herpes simplex virus infection in the brain

24 September 2018

1 reference

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Viruses selectively upregulate Toll-like receptors in the central nervous system.

24 September 2018

1 reference

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Toll-like receptor 3 promotes cross-priming to virus-infected cells.

24 September 2018

1 reference

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Does Toll-like receptor 3 play a biological role in virus infections?

24 September 2018

1 reference

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Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9.

24 September 2018

1 reference

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Broad expression of Toll-like receptors in the human central nervous system

24 September 2018

1 reference

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Severe herpesvirus infections in an adolescent without natural killer cells

24 September 2018

1 reference

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TLR signaling tailors innate immune responses in human microglia and astrocytes

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314467

Differential activation of astrocytes by innate and adaptive immune stimuli

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22426207

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Toll-like receptor 3 immune deficiency may be causative for HSV-2-associated mollaret meningitis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22426207

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI60893

1 reference

10 August 2017

1 reference

10 August 2017

1 reference