Defective TFH Cell Function and Increased TFR Cells Contribute to Defective Antibody Production in Aging (Q35858488)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26146074%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

title

Defective TFH Cell Function and Increased TFR Cells Contribute to Defective Antibody Production in Aging (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26146074%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

main subject

T follicular helper cell

1 reference

0 references

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26146074%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

3

Gordon J Freeman

1 reference

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18 February 2020

4

Marcia Haigis

1 reference

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18 February 2020

author name string

Peter T Sage

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26146074%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Catherine L Tan

series ordinal

2

1 reference

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18 February 2020

publication date

2 July 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26146074%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference

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18 February 2020

volume

12

1 reference

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18 February 2020

page(s)

163-171

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18 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26146074%20AND%20SRC:MED&resulttype=core&format=json

The coinhibitory receptor CTLA-4 controls B cell responses by modulating T follicular helper, T follicular regulatory, and T regulatory cells.

18 February 2020

cites work

1 reference

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Circulating T follicular regulatory and helper cells have memory-like properties

11 July 2018

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The effect of aging on the frequency, phenotype and cytokine production of human blood CD4 + CXCR5 + T follicular helper cells: comparison of aged and young subjects

11 July 2018

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Foxp3(+) T cells regulate immunoglobulin a selection and facilitate diversification of bacterial species responsible for immune homeostasis

11 July 2018

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Regulatory T cells and the immune aging process: a mini-review

11 July 2018

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Understanding immunosenescence to improve responses to vaccines

11 July 2018

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The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood.

11 July 2018

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11 July 2018

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Regulation of the germinal center reaction by Foxp3+ follicular regulatory T cells

11 July 2018

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Foxp3+ follicular regulatory T cells control the germinal center response.

11 July 2018

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Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions

11 July 2018

1 reference

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Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccine-specific antibodies

11 July 2018

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Follicular helper CD4 T cells (TFH)

11 July 2018

1 reference

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A major role for Bim in regulatory T cell homeostasis.

11 July 2018

1 reference

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Partial restoration of T-cell function in aged mice by in vitro blockade of the PD-1/ PD-L1 pathway

11 July 2018

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B7-H1 expression on old CD8+ T cells negatively regulates the activation of immune responses in aged animals.

11 July 2018

1 reference

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Bcl6 mediates the development of T follicular helper cells

11 July 2018

1 reference

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CD4+CD25+Foxp3+ T cells and CD4+CD25-Foxp3+ T cells in aged mice

11 July 2018

1 reference

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11 July 2018

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11 July 2018

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CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorly

11 July 2018

1 reference

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Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice

11 July 2018

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Failure to respond to influenza vaccine in the aged: correlation with B-cell number and function

11 July 2018

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Immunological studies of aging. II. Loss of IgG and high avidity plaque-forming cells and increased suppressor cell activity in aging mice

11 July 2018

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In vitro assay to sensitively measure T(FR) suppressive capacity and T(FH) stimulation of B cell responses.

11 July 2018

1 reference

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24 September 2018

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Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer's patches.

24 September 2018

1 reference

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Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3.

24 September 2018

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The decline in B lymphopoiesis in aged mice reflects loss of very early B-lineage precursors.

24 September 2018

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Thymus cell migration. Quantitative aspects of cellular traffic from the thymus to the periphery in mice

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26146074

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELREP.2015.06.015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26146074%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26146074%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26146074%20AND%20SRC:MED&resulttype=core&format=json