Galanin receptor subtype 2 suppresses cell proliferation and induces apoptosis in p53 mutant head and neck cancer cells. (Q35860804)

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23 January 2020

title

Galanin receptor subtype 2 suppresses cell proliferation and induces apoptosis in p53 mutant head and neck cancer cells (English)

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23 January 2020

1 reference

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head and neck carcinoma

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10

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23 January 2020

author name string

Takeharu Kanazawa

1

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23 January 2020

Pavan K Kommareddi

2

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23 January 2020

Toshihide Iwashita

3

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23 January 2020

Bhavna Kumar

4

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23 January 2020

Kiyoshi Misawa

5

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23 January 2020

Yuki Misawa

6

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23 January 2020

Ilwhan Jang

7

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23 January 2020

Thankam S Nair

8

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23 January 2020

Yukiko Iino

9

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23 January 2020

language of work or name

English

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publication date

10 March 2009

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23 January 2020

published in

Clinical Cancer Research

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23 January 2020

volume

15

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23 January 2020

issue

7

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23 January 2020

page(s)

2222-2230

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Galanin decreases proliferation of PC12 cells and induces apoptosis via its subtype 2 receptor (GalR2).

23 January 2020

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SOX2 is frequently downregulated in gastric cancers and inhibits cell growth through cell-cycle arrest and apoptosis

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Galanin and galanin receptor type 1 suppress proliferation in squamous carcinoma cells: activation of the extracellular signal regulated kinase pathway and induction of cyclin-dependent kinase inhibitors.

11 July 2018

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G-protein-coupled OX1 orexin/hcrtr-1 hypocretin receptors induce caspase-dependent and -independent cell death through p38 mitogen-/stress-activated protein kinase

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Identification of a lipid peroxidation product as a potential trigger of the p53 pathway

11 July 2018

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Potent induction of apoptosis in human hepatoma cell lines by targeted cytotoxic somatostatin analogue AN-238.

11 July 2018

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p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2.

11 July 2018

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In vitro effects of the BH3 mimetic, (-)-gossypol, on head and neck squamous cell carcinoma cells.

11 July 2018

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Loss of chromosome arm 18q with tumor progression in head and neck squamous cancer.

11 July 2018

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Galanin receptor subtype GalR2 mediates apoptosis in SH-SY5Y neuroblastoma cells

11 July 2018

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Angiotensin II induces apoptosis in renal proximal tubular cells

11 July 2018

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Beta-arrestin 2 functions as a G-protein-coupled receptor-activated regulator of oncoprotein Mdm2

11 July 2018

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The role of the cyclin-dependent kinase inhibitor p21 in apoptosis.

11 July 2018

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Regulation of Raf-Akt Cross-talk

11 July 2018

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The galanin receptor type 2 initiates multiple signaling pathways in small cell lung cancer cells by coupling to G(q), G(i) and G(12) proteins

11 July 2018

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E1A is sufficient by itself to induce apoptosis independent of p53 and other adenoviral gene products.

11 July 2018

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Overexpression of cyclin D1 messenger RNA predicts for poor prognosis in estrogen receptor-positive breast cancer

11 July 2018

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Apoptosis in neuronal cells: role of caspases

11 July 2018

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Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors

11 July 2018

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p57(kip2) expression is related to carcinogenesis and tumor progression in laryngeal tissues.

11 July 2018

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Reversal of cisplatin resistance with a BH3 mimetic, (-)-gossypol, in head and neck cancer cells: role of wild-type p53 and Bcl-xL.

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Arrestins block G protein-coupled receptor-mediated apoptosis

24 September 2018

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The gene ratios c-MYC:cyclin-dependent kinase (CDK)N2A and CCND1:CDKN2A correlate with poor prognosis in squamous cell carcinoma of the head and neck

24 September 2018

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24 September 2018

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Effects of cyclin D1 polymorphism on age of onset of hereditary nonpolyposis colorectal cancer

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12 December 2020

Identification of new minimally lost regions on 18q in head and neck squamous cell carcinoma

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12 December 2020

Prognostic significance of p27KIP1 protein and ki-67 growth fraction in non-small cell lung cancers

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12 December 2020

Combined therapy with conservative surgery, radiotherapy, and regional chemotherapy for maxillary sinus carcinoma

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12 December 2020

Loss of p27Kip1 expression is a strong independent prognostic factor of reduced survival in N0 gastric carcinomas

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12 December 2020

Galanin, neurotensin, and phorbol esters rapidly stimulate activation of mitogen-activated protein kinase in small cell lung cancer cells

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12 December 2020

p27Kip1 overexpression causes apoptotic death of mammalian cells

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12 December 2020

Inhibition by galanin of experimental carcinogenesis induced by azaserine in rat pancreas

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12 December 2020

Low p27 expression correlates with poor prognosis for patients with oral tongue squamous cell carcinoma

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12 December 2020

10.1158/1078-0432.CCR-08-2443

Identifiers

DOI

1 reference

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23 January 2020

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23 January 2020

PubMed publication ID

19276245

1 reference