Human Anti-CD40 Antibody and Poly IC:LC Adjuvant Combination Induces Potent T Cell Responses in the Lung of Nonhuman Primates (Q35864569)

10 August 2017

Human Anti-CD40 Antibody and Poly IC:LC Adjuvant Combination Induces Potent T Cell Responses in the Lung of Nonhuman Primates (English)

1 reference

10 August 2017

5

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14 June 2020

7

Richard A Koup

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14 June 2020

author name string

Elizabeth A Thompson

1

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14 June 2020

Frank Liang

2

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14 June 2020

Gustaf Lindgren

3

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14 June 2020

Kerrie J Sandgren

4

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14 June 2020

Patricia A Darrah

6

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14 June 2020

Robert A Seder

8

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14 June 2020

Ross M Kedl

9

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14 June 2020

Karin Loré

10

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14 June 2020

language of work or name

English

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publication date

29 June 2015

1 reference

10 August 2017

Journal of Immunology

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14 June 2020

volume

195

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issue

3

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page(s)

1015-1024

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Role of crosslinking for agonistic CD40 monoclonal antibodies as immune therapy of cancer

14 June 2020

cites work

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DNA/long peptide vaccination against conserved regions of SIV induces partial protection against SIVmac251 challenge

11 July 2018

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11 July 2018

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11 July 2018

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Polyinosinic-polycytidylic acid is the most effective TLR adjuvant for SIV Gag protein-induced T cell responses in nonhuman primates

11 July 2018

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Phase I study of the CD40 agonist antibody CP-870,893 combined with carboplatin and paclitaxel in patients with advanced solid tumors

11 July 2018

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11 July 2018

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Persistent antigen at vaccination sites induces tumor-specific CD8⁺ T cell sequestration, dysfunction and deletion

11 July 2018

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Comparative analysis of the magnitude, quality, phenotype, and protective capacity of simian immunodeficiency virus gag-specific CD8+ T cells following human-, simian-, and chimpanzee-derived recombinant adenoviral vector immunization

11 July 2018

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Vaccine-elicited CD8+ T cells protect against respiratory syncytial virus strain A2-line19F-induced pathogenesis in BALB/c mice

11 July 2018

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11 July 2018

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Phase I study of the anti-CD40 humanized monoclonal antibody lucatumumab (HCD122) in relapsed chronic lymphocytic leukemia

11 July 2018

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CD27 stimulation promotes the frequency of IL-7 receptor-expressing memory precursors and prevents IL-12-mediated loss of CD8(+) T cell memory in the absence of CD4(+) T cell help

11 July 2018

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Type I IFN-dependent T cell activation is mediated by IFN-dependent dendritic cell OX40 ligand expression and is independent of T cell IFNR expression.

11 July 2018

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Immune modulation with weekly dosing of an agonist CD40 antibody in a phase I study of patients with advanced solid tumors

11 July 2018

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Long peptides induce polyfunctional T cells against conserved regions of HIV-1 with superior breadth to single-gene vaccines in macaques.

11 July 2018

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A phase I study of dacetuzumab (SGN-40, a humanized anti-CD40 monoclonal antibody) in patients with chronic lymphocytic leukemia.

11 July 2018

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Multiple innate signaling pathways cooperate with CD40 to induce potent, CD70-dependent cellular immunity

11 July 2018

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Activation of human B cells by the agonist CD40 antibody CP-870,893 and augmentation with simultaneous toll-like receptor 9 stimulation

11 July 2018

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Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia

11 July 2018

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Phase I study of the humanized anti-CD40 monoclonal antibody dacetuzumab in refractory or recurrent non-Hodgkin's lymphoma

11 July 2018

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In vivo expansion, persistence, and function of peptide vaccine-induced CD8 T cells occur independently of CD4 T cells

11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates

11 July 2018

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Induction of CD70 on dendritic cells through CD40 or TLR stimulation contributes to the development of CD8+ T cell responses in the absence of CD4+ T cells

11 July 2018

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Combined TLR and CD40 triggering induces potent CD8+ T cell expansion with variable dependence on type I IFN

11 July 2018

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The role of CD40 in peripheral T cell tolerance and immunity

11 July 2018

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11 July 2018

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Immunocytochemical detection of cytokines and chemokines in Langerhans cells and in vitro derived dendritic cells.

11 July 2018

1 reference

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In the absence of a CD40 signal, B cells are tolerogenic.

11 July 2018

1 reference

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Expression of costimulatory ligand CD70 on steady-state dendritic cells breaks CD8+ T cell tolerance and permits effective immunity

11 July 2018

1 reference

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Immunogene therapy by adenovirus vector expressing CD40 ligand for metastatic liver cancer in rats

24 September 2018

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Neutrophils efficiently cross-prime naive T cells in vivo

24 September 2018

1 reference

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Systemic administration of a TLR7 ligand leads to transient immune incompetence due to peripheral-blood leukocyte depletion.

24 September 2018

1 reference

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Response of in vivo protein synthesis in T lymphocytes and leucocytes to an endotoxin challenge in healthy volunteers.

24 September 2018

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Combined TLR/CD40 stimulation mediates potent cellular immunity by regulating dendritic cell expression of CD70 in vivo

24 September 2018

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12 December 2020

Activation of human T cells by major histocompatability complex class II expressing neutrophils: proliferation in the presence of superantigen, but not tetanus toxoid

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In vivo induction of HLA-DR on human neutrophils in patients treated with interferon-gamma

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The CD40 agonist antibody CP-870,893 enhances dendritic cell and B-cell activity and promotes anti-tumor efficacy in SCID-hu mice

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Type I interferons directly regulate lymphocyte recirculation and cause transient blood lymphopenia

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Blood dendritic cells generated with Flt3 ligand and CD40 ligand prime CD8+ T cells efficiently in cancer patients

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Identifiers

DOI

10.4049/JIMMUNOL.1500078

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26123354%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26123354%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

1 reference

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