Application of physiologically based pharmacokinetic models in chemical risk assessment (Q35864986)

10 August 2017

Application of physiologically based pharmacokinetic models in chemical risk assessment (English)

1 reference

10 August 2017

chemical risk assessment

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inferred from title

object named as

chemical risk assessment

14 July 2023

1 reference

Moiz Mumtaz

1

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10 August 2017

Jeffrey Fisher

series ordinal

2

1 reference

10 August 2017

Benjamin Blount

series ordinal

3

1 reference

10 August 2017

Patricia Ruiz

series ordinal

4

1 reference

10 August 2017

19 March 2012

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10 August 2017

Journal of toxicology

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10 August 2017

2012

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10 August 2017

904603

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Creative Commons Attribution 3.0 Unported

10 August 2017

start time

1 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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PBPK modeling of complex hydrocarbon mixtures: gasoline

11 July 2018

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Have physiologically-based pharmacokinetic models delivered?

11 July 2018

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11 July 2018

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The use of in vitro toxicity data and physiologically based kinetic modeling to predict dose-response curves for in vivo developmental toxicity of glycol ethers in rat and man.

11 July 2018

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Chemical-specific screening criteria for interpretation of biomonitoring data for volatile organic compounds (VOCs)--application of steady-state PBPK model solutions

11 July 2018

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Interpreting NHANES biomonitoring data, cadmium

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Computational toxicology of chloroform: reverse dosimetry using Bayesian inference, Markov chain Monte Carlo simulation, and human biomonitoring data.

11 July 2018

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11 July 2018

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A biologically based dose-response model for dietary iodide and the hypothalamic-pituitary-thyroid axis in the adult rat: evaluation of iodide deficiency

11 July 2018

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Development of a screening approach to interpret human biomonitoring data on volatile organic compounds: reverse dosimetry on biomonitoring data for trichloroethylene

11 July 2018

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Physiologically based approaches towards the prediction of pharmacokinetics: in vitro-in vivo extrapolation

11 July 2018

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Integration of in vitro neurotoxicity data with biokinetic modelling for the estimation of in vivo neurotoxicity

11 July 2018

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Reverse dosimetry: interpreting trihalomethanes biomonitoring data using physiologically based pharmacokinetic modeling

11 July 2018

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Biomonitoring equivalents: a screening approach for interpreting biomonitoring results from a public health risk perspective

11 July 2018

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Use of a physiologically based pharmacokinetic model to identify exposures consistent with human biomonitoring data for chloroform

11 July 2018

1 reference

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Evaluation of physiologically based pharmacokinetic models in risk assessment: an example with perchloroethylene

11 July 2018

1 reference

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Framework for evaluation of physiologically-based pharmacokinetic models for use in safety or risk assessment

11 July 2018

1 reference

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Reconstructing population exposures from dose biomarkers: inhalation of trichloroethylene (TCE) as a case study.

11 July 2018

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Toxicokinetics and physiologically based toxicokinetics in toxicology and risk assessment

11 July 2018

1 reference

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The integration of data on physico-chemical properties, in vitro-derived toxicity data and physiologically based kinetic and dynamic as modelling a tool in hazard and risk assessment. A commentary.

11 July 2018

1 reference

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Comparison of cancer risk estimates for vinyl chloride using animal and human data with a PBPK model.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317240

A toxicokinetic model for predicting the tissue distribution and elimination of organic and inorganic mercury following exposure to methyl mercury in animals and humans. II. Application and validation of the model in humans

11 July 2018

1 reference

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A toxicokinetic model for predicting the tissue distribution and elimination of organic and inorganic mercury following exposure to methyl mercury in animals and humans. I. Development and validation of the model using experimental data in rats

11 July 2018

1 reference

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Development of a physiologically based pharmacokinetic model of trichloroethylene and its metabolites for use in risk assessment

11 July 2018

1 reference

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Exposure estimates to disinfection by-products of chlorinated drinking water

11 July 2018

1 reference

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Estimation of toxicity of chemical mixtures through modeling of chemical interactions

11 July 2018

1 reference

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Investigation of the potential impact of benchmark dose and pharmacokinetic modeling in noncancer risk assessment

11 July 2018

1 reference

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Physiological parameter values for physiologically based pharmacokinetic models

11 July 2018

1 reference

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Using structural information to create physiologically based pharmacokinetic models for all polychlorinated biphenyls

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317240

Linking a PBPK model for chloroform with measured breath concentrations in showers: implications for dermal exposure models

11 July 2018

1 reference

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Development of physiologically based pharmacokinetic and physiologically based pharmacodynamic models for applications in toxicology and risk assessment.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317240

Assessment of effect levels of chemicals from quantitative structure-activity relationship (QSAR) models. I. Chronic lowest-observed-adverse-effect level (LOAEL).

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317240

A weight-of-evidence approach for assessing interactions in chemical mixtures

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317240

Tissue Weights and Rates of Blood Flow in Man for the Prediction of Anesthetic Uptake and Distribution

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317240

Linking indoor air and pharmacokinetic models to assess tetrachloroethylene risk

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317240

A preliminary pharmacokinetic model for several chlorinated biphenyls in the rat

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317240

PBPK models in risk assessment--A focus on chloroprene.

11 July 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F904603

Assessing the toxic effects of ethylene glycol ethers using Quantitative Structure Toxicity Relationship models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F904603

Application of physiologically-based pharmacokinetic modeling to investigate the toxicological interaction between chlorpyrifos and parathion in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F904603

Evaluation of potential toxicity from co-exposure to three CNS depressants (toluene, ethylbenzene, and xylene) under resting and working conditions using PBPK modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F904603

Translational research to develop a human PBPK models tool kit-volatile organic compounds (VOCs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F904603

Physiologically-based pharmacokinetic modeling of benzene in humans: a Bayesian approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F904603

Revised assessment of cancer risk to dichloromethane II. Application of probabilistic methods to cancer risk determinations

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F904603

A human physiologically based pharmacokinetic model for trichloroethylene and its metabolites, trichloroacetic acid and free trichloroethanol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F904603

Urinary cadmium elimination as a biomarker of exposure for evaluating a cadmium dietary exposure--biokinetics model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F904603

Biokinetic modeling and in vitro-in vivo extrapolations

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F904603

Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F904603

The use of Markov chain Monte Carlo uncertainty analysis to support a Public Health Goal for perchloroethylene

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F904603

Using structural information to create physiologically based pharmacokinetic models for all polychlorinated biphenyls. II. Rates of metabolism

21 January 2018

1 reference

12 December 2020

A kinetic model of cadmium metabolism in the human being

1 reference

12 December 2020

Physiologically based pharmacokinetic modeling of the temperature-dependent dermal absorption of chloroform by humans following bath water exposures

1 reference

12 December 2020

Pharmacokinetics/pharmacodynamics (PK/PD) modeling of risks of kidney toxicity from exposure to cadmium: estimates of dietary risks in the U.S. population

1 reference

12 December 2020

Development of a human physiologically based pharmacokinetic (PBPK) model for inorganic arsenic and its mono- and di-methylated metabolites

1 reference

12 December 2020

Comparative metabolism of carbon tetrachloride in rats, mice, and hamsters using gas uptake and PBPK modeling

1 reference

12 December 2020

Applications of computational toxicology methods at the Agency for Toxic Substances and Disease Registry

1 reference

12 December 2020

Physiologically based pharmacokinetic (PBPK) tool kit for environmental pollutants--metals

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12 December 2020

Computational toxicology methods in public health practice

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12 December 2020

Identifiers

DOI

10.1155/2012/904603

1 reference

10 August 2017

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10 August 2017

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