Roles of DNA topoisomerase II isozymes in chemotherapy and secondary malignancies. (Q35865072)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17578914%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

title

Roles of DNA topoisomerase II isozymes in chemotherapy and secondary malignancies (English)

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1 January 2020

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7

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1 January 2020

author name string

Anna M Azarova

1

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1 January 2020

Yi Lisa Lyu

2

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1 January 2020

Chao-Po Lin

3

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1 January 2020

Yuan-Chin Tsai

4

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1 January 2020

Johnson Yiu-Nam Lau

5

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1 January 2020

James C Wang

6

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1 January 2020

language of work or name

English

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publication date

19 June 2007

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Proceedings of the National Academy of Sciences of the United States of America

1 January 2020

published in

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1 January 2020

volume

104

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1 January 2020

issue

26

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page(s)

11014-11019

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Role of apoptotic nuclease caspase-activated DNase in etoposide-induced treatment-related acute myelogenous leukemia

1 January 2020

cites work

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Role of topoisomerase IIbeta in the expression of developmentally regulated genes.

27 July 2018

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Cleavage of the MLL gene by activators of apoptosis is independent of topoisomerase II activity

27 July 2018

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Etoposide, topoisomerase II and cancer

27 July 2018

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Characterization of genomic breakpoints in MLL and CBP in leukemia patients with t(11;16).

27 July 2018

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Aberrant lamination in the cerebral cortex of mouse embryos lacking DNA topoisomerase IIbeta

27 July 2018

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Acidic pH induces topoisomerase II-mediated DNA damage.

27 July 2018

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Apoptotic stimuli initiate MLL-AF9 translocations that are transcribed in cells capable of division.

27 July 2018

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Genetic pathways in therapy-related myelodysplasia and acute myeloid leukemia

27 July 2018

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Nucleolytic cleavage of the mixed lineage leukemia breakpoint cluster region during apoptosis.

27 July 2018

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Tumor cell death induced by topoisomerase-targeting drugs.

27 July 2018

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Immunohistochemical analyses of DNA topoisomerase II isoforms in developing rat cerebellum

27 July 2018

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Sonic hedgehog regulates growth and morphogenesis of the tooth

27 July 2018

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Topoisomerase II is required for mitoxantrone to signal nuclear factor kappa B activation in HL60 cells.

27 July 2018

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DNA structural properties of AF9 are similar to MLL and could act as recombination hot spots resulting in MLL/AF9 translocations and leukemogenesis

27 July 2018

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Reduction of collagen type I in the ciliary muscle of inflamed monkey eyes

27 July 2018

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Etoposide targets topoisomerase IIalpha and IIbeta in leukemic cells: isoform-specific cleavable complexes visualized and quantified in situ by a novel immunofluorescence technique

27 July 2018

1 reference

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DNA cleavage within the MLL breakpoint cluster region is a specific event which occurs as part of higher-order chromatin fragmentation during the initial stages of apoptosis

27 July 2018

1 reference

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Antigen retrieval in cryostat tissue sections and cultured cells by treatment with sodium dodecyl sulfate (SDS).

27 July 2018

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Novel HeLa topoisomerase II is the II beta isoform: complete coding sequence and homology with other type II topoisomerases.

27 July 2018

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Sequence analysis of the breakpoint cluster region in the ALL-1 gene involved in acute leukemia.

27 July 2018

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Differential expressions of the topoisomerase II alpha and II beta mRNAs in developing rat brain

27 July 2018

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A topoisomerase II-dependent G2 cycle checkpoint in mammalian cells/.

27 July 2018

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DNA topoisomerase II mutant of Saccharomyces cerevisiae: topoisomerase II is required for segregation of daughter molecules at the termination of DNA replication

27 July 2018

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DNA topoisomerase II is required at the time of mitosis in yeast

27 July 2018

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Cloning and sequencing of cDNA encoding human DNA topoisomerase II and localization of the gene to chromosome region 17q21-22

27 July 2018

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Cloning of ALL-1, the locus involved in leukemias with the t(4;11)(q21;q23), t(9;11)(p22;q23), and t(11;19)(q23;p13) chromosome translocations

27 July 2018

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Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias

27 July 2018

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Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

27 July 2018

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Different patterns of gene expression of topoisomerase II isoforms in differentiated tissues during murine development

27 July 2018

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Interleukin 6: insights to its function in skin by overexpression in transgenic mice

27 July 2018

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A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias

27 July 2018

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26 S proteasome-mediated degradation of topoisomerase II cleavable complexes.

27 July 2018

1 reference

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Apoptotic triggers initiate translocations within the MLL gene involving the nonhomologous end joining repair system

24 September 2018

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24 September 2018

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Etoposide metabolites enhance DNA topoisomerase II cleavage near leukemia-associated MLL translocation breakpoints

24 September 2018

1 reference

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Involvement of DNA topoisomerase IIbeta in neuronal differentiation

24 September 2018

1 reference

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The critical role of chromosome translocations in human leukemias.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904155

Site-specific DNA cleavage within the MLL breakpoint cluster region induced by topoisomerase II inhibitors.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904155

Molecular analysis of 13 cases of MLL/11q23 secondary acute leukemia and identification of topoisomerase II consensus-binding sequences near the chromosomal breakpoint of a secondary leukemia with the t(4;11).

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904155

DNA topoisomerase II expression, stability, and phosphorylation in two VM-26-resistant human leukemic CEM sublines

24 September 2018

1 reference

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DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe

24 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0704002104

Drug sensitivity and sequence specificity of human recombinant DNA topoisomerases IIalpha (p170) and IIbeta (p180)

21 January 2018

1 reference

12 December 2020

Secondary leukemias induced by topoisomerase-targeted drugs

1 reference

12 December 2020

An in vivo topoisomerase II cleavage site and a DNase I hypersensitive site colocalize near exon 9 in the MLL breakpoint cluster region

1 reference

12 December 2020

Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: correlation with scaffold attachment regions and topoisomerase II consensus binding sites

1 reference

12 December 2020

HRX involvement in de novo and secondary leukemias with diverse chromosome 11q23 abnormalities

1 reference

12 December 2020

Potential topoisomerase II DNA-binding sites at the breakpoints of a t(9;11) chromosome translocation in acute myeloid leukemia

1 reference

12 December 2020

A protease pathway for the repair of topoisomerase II-DNA covalent complexes

1 reference

12 December 2020

Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II

1 reference

12 December 2020

Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0704002104

1 reference

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1 January 2020

0 references

1 reference

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1 January 2020

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