An essential amino acid residue in the protein translocation channel revealed by targeted random mutagenesis of SecY (Q35865651)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11309495%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

An essential amino acid residue in the protein translocation channel revealed by targeted random mutagenesis of SecY (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11309495%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11309495%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

author name string

K Ito

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11309495%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

language of work or name

English

0 references

publication date

17 April 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11309495%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

6 November 2019

number of pages

6

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

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6 November 2019

volume

98

1 reference

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6 November 2019

issue

9

1 reference

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6 November 2019

page(s)

5128-5133

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11309495%20AND%20SRC:MED&resulttype=core&format=json

The translocon: a dynamic gateway at the ER membrane

6 November 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33175

SecY and SecA interact to allow SecA insertion and protein translocation across the Escherichia coli plasma membrane

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33175

The major pathways of protein translocation across membranes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33175

Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33175

Protein transport across the eukaryotic endoplasmic reticulum and bacterial inner membranes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33175

The SecA and SecY subunits of translocase are the nearest neighbors of a translocating preprotein, shielding it from phospholipids

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33175

Determinants of the quantity of the stable SecY complex in the Escherichia coli cell

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33175

Genetic analysis of SecY: additional export-defective mutations and factors affecting their phenotypes.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33175

A cytoplasmic domain is important for the formation of a SecY-SecE translocator complex

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33175

FtsH is required for proteolytic elimination of uncomplexed forms of SecY, an essential protein translocase subunit

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33175

A mutation affecting the regulation of a secA-lacZ fusion defines a new sec gene.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33175

Characterization of cold-sensitive secY mutants of Escherichia coli

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33175

SecY protein, a membrane-embedded secretion factor of E. coli, is cleaved by the ompT protease in vitro

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33175

The ATPase activity of SecA is regulated by acidic phospholipids, SecY, and the leader and mature domains of precursor proteins

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33175

SecA membrane cycling at SecYEG is driven by distinct ATP binding and hydrolysis events and is regulated by SecD and SecF.

11 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.081617398

Genetic analysis of an essential cytoplasmic domain of Escherichia coli SecY based on resistance to Syd, a SecY-interacting protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.081617398

SecYEG assembles into a tetramer to form the active protein translocation channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.081617398

Genetic dissection of SecA: suppressor mutations against the secY205 translocase defect

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.081617398

Two Independent Mechanisms Down-regulate the Intrinsic SecA ATPase Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.081617398

Oligomeric Rings of the Sec61p Complex Induced by Ligands Required for Protein Translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.081617398

SecY variants that interfere with Escherichia coli protein export in the presence of normal secY

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.081617398

Interaction between SecA and SecYEG in Micellar Solution and Formation of the Membrane-Inserted State†

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.081617398

Protein translocation functions of Escherichia coli SecY: in vitro characterization of cold-sensitive secY mutants

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11309495

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.081617398

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11309495%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11309495%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

PubMed publication ID

11309495

1 reference