Chronic human immunodeficiency virus type 1 infection of myeloid cells disrupts the autoregulatory control of the NF-kappaB/Rel pathway via enhanced IkappaBalpha degradation (Q35865967)

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scientific article published in August 1996

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English	Chronic human immunodeficiency virus type 1 infection of myeloid cells disrupts the autoregulatory control of the NF-kappaB/Rel pathway via enhanced IkappaBalpha degradation	scientific article published in August 1996

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scholarly article

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18 October 2019

Chronic human immunodeficiency virus type 1 infection of myeloid cells disrupts the autoregulatory control of the NF-kappaB/Rel pathway via enhanced IkappaBalpha degradation (English)

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18 October 2019

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C DeLuca

1

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18 October 2019

A Roulston

2

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18 October 2019

A Koromilas

3

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M A Wainberg

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J Hiscott

5

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1 August 1996

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18 October 2019

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11

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Journal of Virology

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70

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5183-5193

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18 October 2019

Permanent occupancy of the human immunodeficiency virus type 1 enhancer by NF-kappa B is needed for persistent viral replication in monocytes.

1 reference

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Human PKR transfected into murine cells stimulates expression of genes under control of the HIV1 or HTLV-I LTR.

1 reference

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The inducible transcription factor NF-kappa B: structure-function relationship of its protein subunits

1 reference

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Chronic human immunodeficiency virus type 1 infection stimulates distinct NF-kappa B/rel DNA binding activities in myelomonoblastic cells.

1 reference

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Promoter analysis of the gene encoding the I kappa B-alpha/MAD3 inhibitor of NF-kappa B: positive regulation by members of the rel/NF-kappa B family

1 reference

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The macrophage and HIV-1.

1 reference

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The I kappa B proteins: multifunctional regulators of Rel/NF-kappa B transcription factors

1 reference

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Virus induction of NF-kappa B/Rel proteins and type I interferon gene expression in myelomonoblastic cells

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The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

1 reference

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Disruption of I kappa B alpha regulation by antisense RNA expression leads to malignant transformation

1 reference

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A family of serine proteases expressed exclusively in myelo-monocytic cells specifically processes the nuclear factor-kappa B subunit p65 in vitro and may impair human immunodeficiency virus replication in these cells

1 reference

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Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

1 reference

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11 July 2018

Phosphorylation of I kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa B

1 reference

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11 July 2018

In vivo stimulation of I kappa B phosphorylation is not sufficient to activate NF-kappa B

1 reference

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Regulation of I kappa B alpha and p105 in monocytes and macrophages persistently infected with human immunodeficiency virus

1 reference

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11 July 2018

Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190474

11 July 2018

Inducible degradation of I kappa B alpha in vitro and in vivo requires the acidic C-terminal domain of the protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190474

11 July 2018

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190474

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Regulation of human immunodeficiency virus type 1 and cytokine gene expression in myeloid cells by NF-kappa B/Rel transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190474

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HIV-1 Tat directly interacts with the interferon-induced, double-stranded RNA-dependent kinase, PKR

1 reference

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11 July 2018

Differential expression of human interferon genes.

1 reference

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11 July 2018

Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor

1 reference

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Human immunodeficiency virus infection down-regulates HLA class II expression and induces differentiation in promonocytic U937 cells

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Activation of double-stranded RNA-dependent kinase (dsl) by the TAR region of HIV-1 mRNA: a novel translational control mechanism

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Production of tumor necrosis factor alpha and interleukin 1 beta by monocytic cells infected with human immunodeficiency virus

1 reference

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Human immunodeficiency virus infection of monoblastoid cells: cellular differentiation determines the pattern of virus replication

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Regulation of HIV1 replication in promonocytic U937 cells

1 reference

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Coordinate enhancement of cytokine gene expression in human immunodeficiency virus type 1-infected promonocytic cells

1 reference

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The mouse c-rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain

1 reference

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11 July 2018

The DNA binding subunit of NF-kappa B is identical to factor KBF1 and homologous to the rel oncogene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190474

11 July 2018

Control of the interferon-induced 68-kilodalton protein kinase by the HIV-1 tat gene product

1 reference

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11 July 2018

c-rel activates but v-rel suppresses transcription from kappa B sites

1 reference

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11 July 2018

HIV enhancer activity perpetuated by NF-kappa B induction on infection of monocytes

1 reference

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Processing of the precursor of NF-kappa B by the HIV-1 protease during acute infection

1 reference

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Isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-kappa B.

1 reference

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A novel HIV-1 isolate containing alterations affecting the NF-kappa B element

1 reference

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Cloning of the DNA-binding subunit of human nuclear factor kappa B: the level of its mRNA is strongly regulated by phorbol ester or tumor necrosis factor alpha

1 reference

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Induction of NF-KB during monocyte differentiation by HIV type 1 infection.

1 reference

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Negative regulation of human immunodeficiency virus type 1 expression in monocytes: role of the 65-kDa plus 50-kDa NF-kappa B dimer

1 reference

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The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B

1 reference

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Induction of monocytic differentiation and NF-kappa B-like activities by human immunodeficiency virus 1 infection of myelomonoblastic cells

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Human immunodeficiency virus type 1 infection of U937 cells promotes cell differentiation and a new pathway of viral assembly

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Intramolecular masking of the nuclear location signal and dimerization domain in the precursor for the p50 NF-kappa B subunit

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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11 July 2018

The NF-kappa B p65 promoter.

1 reference

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1 reference

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24 September 2018

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1 reference

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12 December 2020

based on heuristic

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Cloning of a mitogen-inducible gene encoding a κB DNA-binding protein with homology to the rel oncogene and to cell-cycle motifs

1 reference

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12 December 2020

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Subcellular redistribution of HTLV-1 Tax protein by NF-kappa B/Rel transcription factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/8764027

12 December 2020

based on heuristic

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Identifiers

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18 October 2019

1 reference

Europe PubMed Central

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18 October 2019

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