Mast cell restricted mouse and human tryptase·heparin complexes hinder thrombin-induced coagulation of plasma and the generation of fibrin by proteolytically destroying fibrinogen (Q35868279)

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scientific article published on 10 January 2012

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English	Mast cell restricted mouse and human tryptase·heparin complexes hinder thrombin-induced coagulation of plasma and the generation of fibrin by proteolytically destroying fibrinogen	scientific article published on 10 January 2012

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20 January 2020

Mast cell restricted mouse and human tryptase·heparin complexes hinder thrombin-induced coagulation of plasma and the generation of fibrin by proteolytically destroying fibrinogen (English)

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20 January 2020

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Alicia Prieto-García

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20 January 2020

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20 January 2020

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20 January 2020

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Wei Xing

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20 January 2020

William S Lane

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20 January 2020

Kyungmee Chung

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20 January 2020

Paul Anderson

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20 January 2020

Philip M Hansbro

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20 January 2020

Mariana Castells

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20 January 2020

Richard L Stevens

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20 January 2020

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10 January 2012

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20 January 2020

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11

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Journal of Biological Chemistry

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20 January 2020

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20 January 2020

11

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20 January 2020

7834-7844

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20 January 2020

Mast cell tryptase deficiency attenuates mouse abdominal aortic aneurysm formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Essential role for mast cell tryptase in acute experimental colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Synovial fibroblasts promote the expression and granule accumulation of tryptase via interleukin-33 and its receptor ST-2 (IL1RL1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Crystal structure of human fibrinogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Mast cells contribute to autoimmune inflammatory arthritis via their tryptase/heparin complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Alternate mRNA splicing in multiple human tryptase genes is predicted to regulate tetramer formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Mouse mast cell tryptase mMCP-6 is a critical link between adaptive and innate immunity in the chronic phase of Trichinella spiralis infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Mouse chromosome 17A3.3 contains 13 genes that encode functional tryptic-like serine proteases with distinct tissue and cell expression patterns

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Tryptase inhibition blocks airway inflammation in a mouse asthma model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Definition of the extended substrate specificity determinants for beta-tryptases I and II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Evaluation of the substrate specificity of human mast cell tryptase beta I and demonstration of its importance in bacterial infections of the lung

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Abnormal mast cells in mice deficient in a heparin-synthesizing enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Heparin is essential for the storage of specific granule proteases in mast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Human tryptases alpha and beta/II are functionally distinct due, in part, to a single amino acid difference in one of the surface loops that forms the substrate-binding cleft

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Human beta-tryptase is a ring-like tetramer with active sites facing a central pore

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Human mast cell tryptase fibrinogenolysis: kinetics, anticoagulation mechanism, and cell adhesion disruption

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Induction of a selective and persistent extravasation of neutrophils into the peritoneal cavity by tryptase mouse mast cell protease 6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

The tryptase, mouse mast cell protease 7, exhibits anticoagulant activity in vivo and in vitro due to its ability to degrade fibrinogen in the presence of the diverse array of protease inhibitors in plasma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Fate of two mast cell tryptases in V3 mastocytosis and normal BALB/c mice undergoing passive systemic anaphylaxis: prolonged retention of exocytosed mMCP-6 in connective tissues, and rapid accumulation of enzymatically active mMCP-7 in the blood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Isolation and characterization of ryudocan and syndecan heparan sulfate proteoglycans, core proteins, and cDNAs from a rat endothelial cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Substrates for determination of trypsin, thrombin and thrombin-like enzymes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Biochemical and microscopic evidence for the internalization and degradation of heparin-containing mast cell granules by bovine endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

The fibrinogenolytic activity of purified tryptase from human lung mast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Different mouse mast cell populations express various combinations of at least six distinct mast cell serine proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Cloning and characterization of a second complementary DNA for human tryptase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Molecular cloning of the mouse mast cell protease-5 gene. A novel secretory granule protease expressed early in the differentiation of serosal mast cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Interactions of human mast cell tryptase with biological protease inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Isolation, characterization, and transcription of the gene encoding mouse mast cell protease 7

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Increased uptake and desulphation of heparin by mouse macrophages in the presence of polycations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

27 July 2018

Natural disruption of the mouse mast cell protease 7 gene in the C57BL/6 mouse

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.325712

21 January 2018

The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infections

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.325712

21 January 2018

The mouse mast cell-restricted tetramer-forming tryptases mouse mast cell protease 6 and mouse mast cell protease 7 are critical mediators in inflammatory arthritis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.325712

21 January 2018

Treatment of mildly to moderately active ulcerative colitis with a tryptase inhibitor (APC 2059): an open-label pilot study

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https://api.crossref.org/works/10.1074%2FJBC.M111.325712

21 January 2018

Mast cell inhibitor cromolyn increases blood clotting and hypoxia in murine breast cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.325712

21 January 2018

Interleukin 3: A differentiation and growth factor for the mouse mast cell that contains chondroitin sulfate E proteoglycan

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24 September 2018

Cloning of the cDNA and gene of mouse mast cell protease-6. Transcription by progenitor mast cells and mast cells of the connective tissue subclass.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318743

24 September 2018

Tryptase from human pulmonary mast cells. Purification and characterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/22235124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degradation of the heparin matrix of mast cell granules by cultured fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/22235124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pediatric mastocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22235124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombin is inactivated by mast cell secretory granule chymase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22235124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of expression of the tryptase mouse mast cell protease 7 in mast cells of the C57BL/6J mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/22235124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant human mast cell tryptase beta: stable expression in Pichia pastoris and purification of fully active enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/22235124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-tryptase treatment using nafamostat mesilate has a therapeutic effect on experimental colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22235124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1074/JBC.M111.325712

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20 January 2020

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20 January 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235124%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

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