Obesity Suppresses Estrogen Receptor Beta Expression in Breast Cancer Cells via a HER2-Mediated Pathway (Q35879517)

10 August 2017

Obesity Suppresses Estrogen Receptor Beta Expression in Breast Cancer Cells via a HER2-Mediated Pathway (English)

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10 August 2017

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Laura W Bowers

1

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10 August 2017

Megan Wiese

2

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10 August 2017

Andrew J Brenner

3

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10 August 2017

Emily L Rossi

4

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10 August 2017

Rajeshwar R Tekmal

5

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10 August 2017

Stephen D Hursting

6

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10 August 2017

Linda A deGraffenried

7

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10 August 2017

language of work or name

English

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publication date

28 December 2015

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10 August 2017

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10 August 2017

10

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10 August 2017

12

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10 August 2017

e0145452

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Creative Commons Attribution 4.0 International

10 August 2017

start time

28 December 2015

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Obesity enhances nongenomic estrogen receptor crosstalk with the PI3K/Akt and MAPK pathways to promote in vitro measures of breast cancer progression

11 July 2018

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The relationship between body composition and response to neoadjuvant chemotherapy in women with operable breast cancer

11 July 2018

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Obesity or overweight is associated with worse pathological response to neoadjuvant chemotherapy among Chinese women with breast cancer

11 July 2018

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Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies

11 July 2018

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Extranuclear signaling by estrogen: role in breast cancer progression and metastasis

11 July 2018

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Interactions between IGF-I, estrogen receptor- (ER ), and ER in regulating growth/apoptosis of MCF-7 human breast cancer cells

11 July 2018

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Effect of obesity on survival of women with breast cancer: systematic review and meta-analysis

11 July 2018

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Leptin/HER2 crosstalk in breast cancer: in vitro study and preliminary in vivo analysis

11 July 2018

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Clinical importance of estrogen receptor-beta evaluation in breast cancer patients treated with adjuvant tamoxifen therapy

11 July 2018

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Co-targeting insulin-like growth factor I receptor and HER2: dramatic effects of HER2 inhibitors on nonoverexpressing breast cancer

11 July 2018

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Estrogen receptor beta: an overview and update

11 July 2018

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Origins of breast cancer subtypes and therapeutic implications

11 July 2018

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Estrogen receptor beta inhibits angiogenesis and growth of T47D breast cancer xenografts

11 July 2018

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Impact of estrogen receptor beta on gene networks regulated by estrogen receptor alpha in breast cancer cells

11 July 2018

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Insulin-like growth factor-I receptor/human epidermal growth factor receptor 2 heterodimerization contributes to trastuzumab resistance of breast cancer cells

11 July 2018

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Low levels of estrogen receptor beta protein predict resistance to tamoxifen therapy in breast cancer

11 July 2018

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Inverse relationship between ER-beta and SRC-1 predicts outcome in endocrine-resistant breast cancer

11 July 2018

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The favourable prognostic value of oestrogen receptor beta immunohistochemical expression in breast cancer

11 July 2018

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Prognostic molecular markers in early breast cancer

11 July 2018

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Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D.

11 July 2018

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New insights into estrogen receptor function in human breast cancer

11 July 2018

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Expression of estrogen receptor beta isoforms in normal breast epithelial cells and breast cancer: regulation by methylation

11 July 2018

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Oestrogen exposure and breast cancer risk

11 July 2018

1 reference

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Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4692402

ER beta inhibits proliferation and invasion of breast cancer cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4692402

Estrogen receptor beta expression in invasive breast cancer

11 July 2018

1 reference

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Cloning and characterization of human estrogen receptor beta promoter

11 July 2018

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Requirement of ErbB2 for signalling by interleukin-6 in prostate carcinoma cells

11 July 2018

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Oncogenic Neu/ErbB-2 increases ets, AP-1, and NF-kappaB-dependent gene expression, and inhibiting ets activation blocks Neu-mediated cellular transformation

11 July 2018

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Obesity increases the incidence of distant metastases in oestrogen receptor-negative human epidermal growth factor receptor 2-positive breast cancer patients.

11 July 2018

1 reference

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Estrogen receptor beta (ER beta) level but not its ER beta cx variant helps to predict tamoxifen resistance in breast cancer

24 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4692402

Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4692402

Clinical significance of the expression of estrogen receptors alpha and beta for endocrine therapy of breast cancer

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4692402

Co-targeting HER2/ErbB2 and insulin-like growth factor-1 receptors causes synergistic inhibition of growth in HER2-overexpressing breast cancer cells

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4692402

Oestrogen receptors alpha and beta differ in normal human breast and breast carcinomas.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4692402

Decreased expression of estrogen receptor beta protein in proliferative preinvasive mammary tumors.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4692402

Altered estrogen receptor alpha and beta messenger RNA expression during human breast tumorigenesis.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4692402

Free insulin-like growth factors in human obesity.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4692402

Obesity at Diagnosis of Breast Carcinoma Influences Duration of Disease-free Survival

24 September 2018

1 reference

12 December 2020

Effect of obesity on total and free insulin-like growth factor (IGF)-1, and their relationship to IGF-binding protein (BP)-1, IGFBP-2, IGFBP-3, insulin, and growth hormone

1 reference

12 December 2020

Expression of estrogen receptor-beta in human breast tumors

1 reference

12 December 2020

Methylation of estrogen receptor beta promoter correlates with loss of ER-beta expression in mammary carcinoma and is an early indication marker in premalignant lesions

1 reference

12 December 2020

Is obesity an independent prognosis factor in woman breast cancer?

1 reference

12 December 2020

Relationship between obesity and pathologic response to neoadjuvant chemotherapy among women with operable breast cancer.

1 reference

12 December 2020

Quantitative analysis of estrogen receptor-alpha and -beta messenger RNA expression in breast carcinoma by real-time polymerase chain reaction

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0145452

Identifiers

DOI

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10 August 2017

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10 August 2017

PubMed publication ID

26709918

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